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Development in the modern world is based on innovation. Many scientists are investigating the problem of innovative development. Most researches agree that innovation is the main driving force for economic and society development, solving environmental problems. The transition to an innovative development model is a priority issue for many countries. Ukraine is no exception, in which the national innovation system has just begun to form. This determines the relevance of the research. The aim of the article is to substantiate the methodological approach to assessing the socioecological and economic system of the country in the conditions of innovative development. In our opinion, the modern trajectory of innovative development is ensured not only by the presence of a national innovation system, but also by the innovativeness of the all sphere of country’s vital activity, the main components of which are the social, ecological and economic systems. The innovativeness of the systems is proposed to be evaluated as an integral indicator, which is calculated of certain indices. The list of indices for economic, social and ecological systems is offered. The EU values with the best result were used as standard. The complex indicator are calculated of integral indicators and allows determining the position of Ukraine in comparison with the EU countries.