<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Epstein-Barr virus (EBV) is a causative agent of infectious mononucleosis syndrome. This infection often resolves over a period of several months without outcomes, but may occasionally be complicated by a great variety of neurologic, hepatic, hematologic and respiratory complications. In the current report, we present the case histories of three patients with acute hepatitis following EBV infection when previously healthy. The patients showed fever, nausea, weakness, as well as yellowing of the skin, and then in the course of examination, sore throat. They were managed supportively and their clinical condition improved. Liver function tests such as ALT, AST, ALP, were undertaken and bilirubin were elevated. The serological tests for EBV infection were consistent with the acute phase of infection. The monospot test was also positive. The patients were managed supportively, and their critical condition was improved.</p></abstract>

Epstein-Barr virus (EBV) is a causative agent of infectious mononucleosis syndrome. This infection often resolves over a period of several months without outcomes, but may occasionally be complicated by a great variety of neurologic, hepatic, hematologic and respiratory complications. In the current report, we present the case histories of three patients with acute hepatitis following EBV infection when previously healthy. The patients showed fever, nausea, weakness, as well as yellowing of the skin, and then in the course of examination, sore throat. They were managed supportively and their clinical condition improved. Liver function tests such as ALT, AST, ALP, were undertaken and bilirubin were elevated. The serological tests for EBV infection were consistent with the acute phase of infection. The monospot test was also positive. The patients were managed supportively, and their critical condition was improved.

Sever hepatitis induced by Epstein-Barr virus: case series

Infectious Diseases and Tropical Medicine Research Center, Health Research Institute

Current Issues in Pharmacy and Medical Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Sever hepatitis induced by Epstein-Barr virus: case series"}

Epstein-Barr virus (EBV) is a causative agent of infectious mononucleosis syndrome. This infection often resolves over a period of several months without...

Sever hepatitis induced by Epstein-Barr virus: case series

Publicado en línea: 11 abr 2018

Páginas: 44 - 46

Recibido: 11 nov 2017

Aceptado: 10 ene 2018

DOI: https://doi.org/10.1515/cipms-2018-0010

Palabras clave
Epstein-Barr virus, hepatitis, serologic tests

© 2018 Mohammad Reza Hasanjani Roushan et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Sever hepatitis induced by Epstein-Barr virus: case series

Publicado en línea: 11 abr 2018

Páginas: 44 - 46

Recibido: 11 nov 2017

Aceptado: 10 ene 2018

DOI: https://doi.org/10.1515/cipms-2018-0010

Palabras claveEpstein-Barr virus, hepatitis, serologic tests

© 2018 Mohammad Reza Hasanjani Roushan et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Palabras clave
Epstein-Barr virus, hepatitis, serologic tests