Genetic diversity of the long terminal repeat of bovine leukaemia virus field isolates
, , y | 30 dic 2015
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Publicado en línea: 30 dic 2015
Páginas: 447 - 450
Recibido: 25 nov 2015
Aceptado: 04 dic 2015
DOI: https://doi.org/10.1515/bvip-2015-0065
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© National Veterinary Research Institute in Pulawy
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In this study the sequences of the long terminal repeat (LTR) of field isolates of the bovine leukaemia virus (BLV) were analysed. These isolates came from emerging cases of BLV infection in cattle from herds having BLV-free status. We found several sequence variations within regulatory motifs in the LTRs like GRE, DAS and interferon binding site. These mutations can possibly affect transcriptional activity of the virus, leading to its silencing.