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Figure 1
Results of molecular cytogenetic analyses for the case with X-autosome translocation (female 1) (A) and X-Y-translocation (female 2) (B) in females. Multicolor banding using a probe for the X-chromosome (MCBX) confirmed the break in Xq22.3; probes for the short arm of chromosome 18 (pcp18) together with a cen-tromeric probe for chromosome 18 (D18Z1) and inverted DAPI-banding mapped the breakpoint into subband 18p11.2. The break in the derivative X-chromosome could be mapped between the probe KAL1 and the subtelomeric probe, and for the Y-chromosome-part in Yq11.22 proximal to probes RP11-943F15.
Figure 2
The EdU-test results are depicted for a normal female (A), a normal male (B), female 1 (C) and female 2 (D). X-Chromosomes are labeled in red by the centromeric probe for the X-chromosome (DXZ1). the inactive X-chromosomes are most intensely stained in green.