<abstract xmlns="http://www.w3.org/1999/xhtml"><p> This report describes a case of a retrobulbar fibrosarcoma in a 4-year-old female sheep. A big tumor was protruding from the orbit but not invading the surrounding tissue and was easily removed surgically. The grayish colored mass was 19×13×8 cm in size and hard. The surface of the tumor was irregular and ulcerated. Marked hemorrhage and necrotic areas were present across the whitish cut surface. Histopathologically, the mass was composed of spindle shaped, anaplastic pleomorphic cells. Masson’s trichrome staining revealed a collagenous matrix in the tissue. Immunohistochemically, the mass was positive for vimentin and proliferating cell nuclear antigen but negative for smooth muscle actin, desmin, glial fibrilar acidic protein and S100 protein antibodies. According to histopathological and immunohistochemical findings the tumor was diagnosed as fibrosarcoma. To the authors’ knowledge, this is the first report of ocular fibrosarcoma in a sheep.</p></abstract>

This report describes a case of a retrobulbar fibrosarcoma in a 4-year-old female sheep. A big tumor was protruding from the orbit but not invading the surrounding tissue and was easily removed surgically. The grayish colored mass was 19×13×8 cm in size and hard. The surface of the tumor was irregular and ulcerated. Marked hemorrhage and necrotic areas were present across the whitish cut surface. Histopathologically, the mass was composed of spindle shaped, anaplastic pleomorphic cells. Masson’s trichrome staining revealed a collagenous matrix in the tissue. Immunohistochemically, the mass was positive for vimentin and proliferating cell nuclear antigen but negative for smooth muscle actin, desmin, glial fibrilar acidic protein and S100 protein antibodies. According to histopathological and immunohistochemical findings the tumor was diagnosed as fibrosarcoma. To the authors’ knowledge, this is the first report of ocular fibrosarcoma in a sheep.

Retrobulbar Fibrosarcoma in a Sheep

Mehmet Akif Ersoy University, Faculty of Veterinary Medicine, Department of Pathology, Istiklal Yerleskesi, 15030, Burdur, Turkey

Mehmet Akif Ersoy University, Faculty of Veterinary Medicine, Department of Surgery, Istiklal Yerleskesi, 15030, Burdur, Turkey

Acta Veterinaria

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Retrobulbar Fibrosarcoma in a Sheep"}

This report describes a case of a retrobulbar fibrosarcoma in a 4-year-old female sheep. A big tumor was protruding from the orbit but not invading the...

Retrobulbar Fibrosarcoma in a Sheep

Publicado en línea: 28 jun 2016

Páginas: 265 - 270

Recibido: 23 nov 2015

Aceptado: 24 feb 2016

DOI: https://doi.org/10.1515/acve-2016-0023

Palabras clave
Retrobulbar fibrosarcoma, histopathology, immunohistochemistry, sheep

© by Ozlem Ozmen

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Retrobulbar Fibrosarcoma in a Sheep

Publicado en línea: 28 jun 2016

Páginas: 265 - 270

Recibido: 23 nov 2015

Aceptado: 24 feb 2016

DOI: https://doi.org/10.1515/acve-2016-0023

Palabras claveRetrobulbar fibrosarcoma, histopathology, immunohistochemistry, sheep

© by Ozlem Ozmen

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Palabras clave
Retrobulbar fibrosarcoma, histopathology, immunohistochemistry, sheep