[1. H. Kataoka and H. L. Lord, Sampling and Sample Preparation for Clinical and Pharmaceutical Analysis, in Sample and Sample Preparation for Field and Laboratory (Ed. J. Pawliszyn), 1st ed., Elsevier, Amsterdam 2002.10.1016/S0166-526X(02)80060-5]Search in Google Scholar
[2. F. Xiaofang, L. Yiping and L. Huwei, Sample preparation for pharmaceutical analysis, 381 (2005) 75–77; DOI: 10.1007/s00216-004-2894-5.10.1007/s00216-004-2894-515599498]Search in Google Scholar
[3. R. F Venn, Physicochemical Properties of Drugs and Metabolites and their Impact on Bioanalysis, in Principles and Practice of Bioanalysis, 2nd ed., CRC Press, New York 2008.]Search in Google Scholar
[4. L. Ohannesian and A. Streeter, Handbook of Pharmaceutical Analysis, Taylor & Francis, New York 2001.10.1201/9780203908389]Search in Google Scholar
[5. N. El-Najjar, R. A. Ketola, T. Nissila, T. Mauriala, M. Antopolsky, J. Janis, H. Gali-Muhtasib, A. Urtti and H. Vuorela, Impact of protein binding on the analytical detectability and anticancer activity of thymoquinone, J. Chem. Biol.4 (2011) 97–107; DOI: 10.1007/s12154-010-0052-4.10.1007/s12154-010-0052-4312462722229047]Search in Google Scholar
[6. T. Li, N. Li, Q. Guo, H. Ji, D. Zhao, S. Xie, X. Li, Z. Qiu, D. Han, X. Chen and Q. You, Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes, Eur. J. Drug Metab. Pharmacokinet. 36 (2011) 249–256; DOI: 10.1007/s13318-011-0050-0.10.1007/s13318-011-0050-021713461]Search in Google Scholar
[7. L. Jian-chun, C. Fei-hu, D. Hai-jun and G. Shu, Study on plasma concentration and bioavailability of wogonin in beagle dogs, Chin. Herbal Med.3 (2011) 144–149; DOI: 10.3969/j.issn.1674-6384.2011.02.010.]Search in Google Scholar
[8. Y. H. Kim, D. W. Jeong, I. B. Paek, H. Y. Ji, Y. C. Kim, D. H. Sohn and H. S. Lee, Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma, J. Chromatogr. B844 (2006) 261–267; DOI: 10.1016/j.jchromb.2006.07.021.10.1016/j.jchromb.2006.07.02116893689]Search in Google Scholar
[9. Y. H. Kim, D. W. Jeong, Y. C. Kim, D. H. Sohn, E. S. Park and H. S. Lee, Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract of Scutellaria baicalensis, PF-2405 in rats, Arch. Pharm. Res. 30 (2007) 260–265.10.1007/BF0297770317366750]Search in Google Scholar
[10. C. Li, L. Zhang, G. Lin and Z. Zuo, Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product, J. Pharm. Biomed. Anal. 54 (2011) 750–758; DOI: 10.1016/j.jpba.2010.10.005.10.1016/j.jpba.2010.10.00521051171]Search in Google Scholar
[11. T. H. Tsai, C. J. Chou, T. R. Tsai and C. F. Chen, Determination of wogonin in rat plasma by liquid chromatography and its pharmacokinetic application, Planta Med. 62 (1996) 263–266; DOI: 10.1055/s-2006-957874.10.1055/s-2006-9578748693042]Search in Google Scholar
[12. FDA (CDER and CVM), Guidance for Industry – Bioanalytical Method Validation, U.S. Department of Health and Human Services – Food and Drug Administration, Rockville (MD) May 2001.]Search in Google Scholar
[13. Z. E. Pápay, Z. Sebestyén, K. Ludányi, N. Kállai, E. Balogh, A. Kósa, S. Somavarapu, B. Böddi and I. Antal, Comparative evaluation of the effect of cyclodextrins and pH on aqueous solubility of apigenin, J. Pharm. Biomed. Anal. 117 (2016) 210–216; DOI: 10.1016/j.jpba.2015.08.019.10.1016/j.jpba.2015.08.01926363816]Search in Google Scholar
[14. J. Sun, F. Li, Y. Zhao, L. Zhao, C. Qiao, Z. Li, Q. Guo and N. Lu, LZ-207, a newly synthesized flavonoid, induces apoptosis and suppresses inflammation-related colon cancer by inhibiting the NF-κB signaling pathway, PLoS ONE10 (2015) e0127282; DOI: 10.1371/journal.pone.0127282.10.1371/journal.pone.0127282]Search in Google Scholar
[15. L. Tingting, K. Guo-jun, H. Hui-ling and Z. Lei, Determination of pKa values of wogonoside, wogonin and oroxylin-A by RP-HPLC, Chin. J. Pharm. Anal. 8 (2014) 1475–1480.]Search in Google Scholar
[16. A. Talbi, D. Zhao, Q. Liu, J. Li, A. Fan, W. Yang, X. Han and X. Chen, Pharmacokinetics, tissue distribution, excretion and plasma protein binding studies of wogonin in rats, Molecules19 (2014) 5538–5549; DOI: 10.3390/molecules19055538.10.3390/molecules19055538]Search in Google Scholar
[17. C. Xiaoyan, W. Hongyan, D. Yue and Z. Dafang, Quantitation of the flavonoid wogonin and its major metabolite wogonin-7β-d-glucuronide in rat plasma by liquid chromatography–tandem mass spectrometry, J. Chromatogr. B775 (2002) 169–178; DOI: 10.1016/S1570-0232(02)00288-X.10.1016/S1570-0232(02)00288-X]Search in Google Scholar
[18. L. Wei, Comparison of the tissue distributions of flavonoids after oral administration of pure baicalin, Radix scutellariae and Scutellariae-Paeoniae couple extracts to rats, J. Med. Plants Res. 5 (2011) 6907–6915; DOI: 10.5897/jmpr11.410.10.5897/JMPR11.410]Search in Google Scholar
[19. L. Tong, M. Wan, L. Zhang, Y. Zhu, H. Sun and K. Bi, Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry, J. Pharm. Biomed. Anal.70 (2012) 6–12; DOI: 10.1016/j.jpba.2012.03.051.10.1016/j.jpba.2012.03.051]Search in Google Scholar
[20. S. N. L. Grace and J. A. J. H. Critchley, The estimation of paracetamol and its major metabolites in both plasma and urine by a single high-performance liquid chromatography assay, J. Pharm. Biomed. Anal. 12 (1994) 1563–1572; DOI: 10.1016/0731-7085(94)00859-0.10.1016/0731-7085(94)00859-0]Search in Google Scholar
[21. S. Y. Fong, Y. C. Wong and Z. Zuo, Development of a SPE-LC/MS/MS method for simultaneous quantification of baicalein, wogonin, oroxylin A and their glucuronides baicalin, wogonoside and oroxyloside in rats and its application to brain uptake and plasma pharmacokinetic studies, J. Pharm. Biomed. Anal. 97 (2014) 9–23; DOI: 10.1016/j.jpba.2014.03.033.10.1016/j.jpba.2014.03.03324803030]Search in Google Scholar
[22. K. Maruyama, H. Nishigor and M. Iwatsuru, Location of drug binding sites on human serum albumin, Chem. Pharm. Bull. 34 (1986) 2989–2993.10.1248/cpb.34.29893769102]Search in Google Scholar
[23. Y. Liu, W. He, W. Gao, Z. Hu and X. Chen, Binding of wogonin to human gamma globulin, Int. J. Biol. Macromol. 37 (2005) 1–11; DOI: 10.1016/j.ijbiomac.2005.04.005.10.1016/j.ijbiomac.2005.04.00516242767]Search in Google Scholar
[24. J. Tian, J. Liu, J. Xie, X. Yao, Z. Hu and X. Chen, Binding of wogonin to human serum albumin: a common binding site of wogonin in subdomain IIA, J. Photochem. Photobiol. B74 (2004) 39–45; DOI: 10.1016/j.jphotobiol.2004.01.001.10.1016/j.jphotobiol.2004.01.00115043845]Search in Google Scholar
[25. J. Tian, J. Liu, Z. Hu and X. Chen, Interaction of wogonin with bovine serum albumin, Bioorg. Med. Chem. 13 (2005) 4124–4129; DOI: 10.1016/j.bmc.2005.02.065.10.1016/j.bmc.2005.02.06515911327]Search in Google Scholar