[1. R. K. Maheshwari, A. K. Singh, J. Gaddipati and R. C. Srimal, Multiple biological activities of curcumin: a short review, Life Sci.78 (2006) 2081–2087; DOI: 10.1016/j.lfs.2005.12.007.10.1016/j.lfs.2005.12.00716413584]Search in Google Scholar
[2. R. Sharma, C. Ireson, R. Verschoyle, K. Hill, M. Williams, C. Leuratti, M. Manson, L. Marnett and W. Steward, Effects of dietary curcumin on glutathione-S-transferase and malondialdehyde-DNA adducts in rat liver and colon mucosa: relationship with drug levels, Clin. Cancer Res.7 (2001) 1452–1458.]Search in Google Scholar
[3. R. A. Sharma, S. A. Euden, S. L. Platton, D. N. Cooke, A. Shafayat, H. R. Hewitt, T. H. Marczylo, B. Morgan and D. Hemingway, Phase I clinical trial of oral curcumin: Biomarkers of systemic activity and compliance, Clin. Cancer Res.10 (2004) 6847–6854.]Search in Google Scholar
[4. A. Paradkar, A. A. Ambike, B. K. Jadhav and K. R. Mahadik, Characterization of curcumin-PVP solid dispersion obtained by spray drying, Int. J. Pharm.271 (2004) 281–286; DOI: 10.1016/j.ijpharm.2003.11.014.10.1016/j.ijpharm.2003.11.01415129995]Search in Google Scholar
[5. M. H. Leung, H. Colangelo and T. W. Kee, Encapsulation of curcumin in cationic micelles suppresses alkaline hydrolysis, Langmuir.24 (2008) 5672–5675; DOI: 10.1021/la800780w.10.1021/la800780w18459746]Search in Google Scholar
[6. T. H. Kim, H. H. Jiang, Y. S. Youn, C. W. Park, K. K. Tak, S. Lee, H. Kim and S. Y. Jon, Preparation and characterization of water-soluble albumin bound curcumin nanoparticles with improved antitumor activity, Int. J. Pharm.403 (2011) 285–591; DOI: 10.1016/j.ijpharm.2010.10.041.10.1016/j.ijpharm.2010.10.04121035530]Search in Google Scholar
[7. Y. B. Pawar, H. Purohit, G. Valicherla, B. Munjal, S. V. Lale, S. Patel and A. K. Bansal, Novel lipid based oral formulation of curcumin: development and optimization by design of experiments approach, Int. J. Pharm.436 (2012) 617–623; DOI: 10.1016/j.ijpharm.2012.07.031.10.1016/j.ijpharm.2012.07.03122842624]Search in Google Scholar
[8. J. Cui, B. Yu, Y. Zhao, W. Zhu, H. Li and H. Lou, Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems, Int. J. Pharm.371 (2009) 148–155; DOI: 10.1016/j.ijpharm.2008.12.009.10.1016/j.ijpharm.2008.12.00919124065]Search in Google Scholar
[9. C. G. Chen, T. D. Johnston, H. Jeon, R. Gedaly, P. P. McHugh, T. G. Burke and D. Ranjan, An in vitro study of liposomal curcumin: stability, toxicity and biological activity in human lymphocytes and Epstein-Barr virus-transformed human B cells, Int. J. Pharm.366 (2009) 133–139; DOI: 10.1016/j.ijpharm.2008.09.009.10.1016/j.ijpharm.2008.09.00918840516]Search in Google Scholar
[10. K. Maiti, K. Mukherjee, A. Gantait, B. Saha and P. K. Mukherjee, Curcumin-phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in rats, Int. J. Pharm.330 (2007) 155–163; DOI: 10.1016/j.ijpharm.]Search in Google Scholar
[11. N. K. Gupta and V. K. Dixit, Bioavailability enhancement of curcumin by complexation with phosphatidylcholine, J. Pharm. Sci.100 (2011) 1987–1995; DOI: 10.1002/jps.22393.10.1002/jps.2239321374628]Search in Google Scholar
[12. J. Zhang, Q. Tang, X. Xu and N. Li, Development and evaluation of a novel phytosome-loaded chitosan microsphere system for curcumin delivery, Int. J. Pharm.448 (2013) 168–174; DOI: 10.1016/j.ijpharm.2013.03.021.10.1016/j.ijpharm.2013.03.02123524117]Search in Google Scholar
[13. P. Shivanand and P. Kinjal, Phytosomes: Technical revolution in phytomedicine, Int. J. PharmaTechRes.2 (2010) 627–631.]Search in Google Scholar
[14. J. Patel, R. Patel, K. Khambholja and N. Patel, An overview of phytosomes as an advanced herbal drug delivery system, Asian J. Pharm. Sci.4 (2009) 363–371.]Search in Google Scholar
[15. A. Semalty, M. Semalty, B. S. Rawat, D. Singh and M. S. Rawat, Pharmacosomes: the lipid-based new drug delivery system, Expert Opin. Drug Deliv.6 (2009) 599–612; DOI: 10.1517/17425240902967607.10.1517/1742524090296760719519287]Search in Google Scholar
[16. http://www.phytosomes.info/public/meriva.asp]Search in Google Scholar
[17. H. I. Benza and W. L. Munyendo, A review of progress and challenges in soft gelatin capsules formulations for oral administration, Int. J. Pharm. Sci. Rev. Res.10 (2011) 20–24.]Search in Google Scholar
[18. R. P. Gullapalli, Soft gelatin capsules (softgels), J. Pharm. Sci.99 (2010) 4109–4121; DOI: 10.1002/jps.22151.10.1002/jps.2215120737624]Search in Google Scholar
[19. W. J. Jones, Softgels: consumer perceptions and market impact relative to other oral dosage forms, Adv. Ther.17 (2000) 213–221.]Search in Google Scholar
[20. L. L. Schramm, Emulsions, Foams, and Suspensions: Fundamentals and Applications, Wiley, Weinheim 2005.10.1002/3527606750]Search in Google Scholar
[21. M. Brewster, R. Vandecruys, J. Peeters, P. Neeskens and G. Verreck, Comparative interaction of 2-hydroxypropyl cyclodextrin and sulfobutylether-cyclodextrin with itraconazole: phase-solubility behavior and stabilization of supersaturated drug solutions, Eur. J. Pharm. Sci.34 (2008) 94–103; DOI: 10.1016/j.ejps.2008.02.007.10.1016/j.ejps.2008.02.00718420390]Search in Google Scholar
[22. M. S. Freag, Y. S. Elnaggar and O. Y. Abdallah, Lyophilized phytosomal nanocarriers as platforms for enhanced diosmin delivery: optimization and ex vivo permeation, Int. J. Nanomed.8 (2013) 2385–2397; DOI: 10.2147/IJN.S45231.10.2147/IJN.S45231370443823861584]Search in Google Scholar
[23. F. Zhang, G. Y. Koh, D. P. Jeansonne, J. Hollingsworth, P. S. Russo, G. Vicente, R. W. Stout and Z. Liu, A novel solubility-enhanced curcumin formulation showing stability and maintenance of anticancer activity, J. Pharm. Sci.100 (2011) 2778–89; DOI: 10.1002/jps.22512.10.1002/jps.2251221312196]Search in Google Scholar
[24. Soybean Phospholipids, in Recent Trends for Enhancing the Diversity and Quality of Soybean (Ed. D. Krezhova), InTech 2011, pp. 483–450.]Search in Google Scholar
[25. Z. Hou, Y. Li, Y. Huang, C. Zhou, J. Lin, Y. Wang, F. Cui, S. Zhou, M. Jia, S. Ye and Q. Zhang, Phytosomes loaded with mitomycin C-soybean phosphatidylcholine complex developed for drug delivery, Mol. Pharm.10 (2013) 90–101; DOI: 10.1021/mp300489p.10.1021/mp300489p23194396]Search in Google Scholar
[26. M. A. Elsheikh, Y. S. Elnaggar, E. Y. Gohar and O. Y. Abdallah, Nanoemulsion liquid preconcentrates for raloxifene hydrochloride: optimization and in vivo appraisal, Int. J. Nanomed.7 (2012) 3787–3802; DOI: 10.2147/IJN.S33186.10.2147/IJN.S33186341422422888234]Search in Google Scholar
[27. X. Ren, X. Mao, L. Si, L. Cao and H. Xiong, Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration, Eur. J. Pharm. Biopharm.70 (2008) 279–288; DOI: 10.1016/j.ejpb.2008.03.019.10.1016/j.ejpb.2008.03.01918499414]Search in Google Scholar
[28. X. Ren, X. Mao, L. Si, L. Cao and J. Qiu, Nonionic surfactants are strong inhibitors of cytochrome P450 3A biotransformation activity in vitro and in vivo, Eur. J. Pharm. Biopharm.36 (2009) 401–411; DOI: 10.1016/j.ejps.2008.11.002.10.1016/j.ejps.2008.11.00219041719]Search in Google Scholar
[29. B. Wahlang, Y. B. Pawar and A. K. Bansal, Identification of permeability-related hurdles in oral delivery of curcumin using the Caco-2 cell model, Eur. J. Pharm. Biopharm.77 (2011) 275–282; DOI: 10.1016/j.ejpb.2010.12.006.10.1016/j.ejpb.2010.12.00621147222]Search in Google Scholar
[30. S. A. Saraf, Applications of novel drug delivery system for herbal formulations, Fitoterapia81 (2010) 680–689; DOI: 10.1016/j.fitote.2010.05.001.10.1016/j.fitote.2010.05.00120471457]Search in Google Scholar