<abstract xmlns="http://www.w3.org/1999/xhtml"><sec><h3>Background</h3><p>Pneumonia causes significant incidence in children younger than 5 years. Most fatalities are resulted from complications. High rates of cardiac events were detected in adult studies but usually related to underlying diseases.</p></sec><sec><h3>Objective</h3><p>To study the cardiac effects of community-acquired pneumonia (CAP) with respiratory failure (RF) in healthy children.</p></sec><sec><h3>Methods</h3><p>The prospective cohort study was conducted in children aged 2–59 months with CAP and RF. Cardiac enzyme assessments, chest radiography, electrocardiography, and echocardiography were performed at the admission date and 2 weeks after admission. t-test and chi-square test were used for comparison between first and second investigations, and the statistically significance level was a <italic>P</italic> &lt;0.05.</p></sec><sec><h3>Results</h3><p>Of the 135 patients, pericardial effusion occurred in 80 (59%), valvular regurgitation in 30 (22%), ST/T changes in 66 (49%), cardiac arrhythmia in 7 (5%), and myocardial injury in 83 (62%). Significant improvement of cardiothoracic-ratio, heart rate, ST/T changes, cardiac arrhythmia, troponin T, myocardial performance, and left-ventricular ejection fraction was demonstrated at second investigations. Three mortality cases exhibited evidence of congestive heart failure (CHF).</p></sec><sec><h3>Conclusion</h3><p>Children with CAP and RF had several cardiac effects even in healthy children. Most cardiac effects were mild and transient. Mortality cases were revealed evidence of congestive heart failure (CHF). Future research should be designed to find out the characteristics and predictors of CHF for early recognition and therapeutic strategy.</p></sec></abstract>

BackgroundPneumonia causes significant incidence in children younger than 5 years. Most fatalities are resulted from complications. High rates of cardiac events were detected in adult studies but usually related to underlying diseases.ObjectiveTo study the cardiac effects of community-acquired pneumonia (CAP) with respiratory failure (RF) in healthy children.MethodsThe prospective cohort study was conducted in children aged 2–59 months with CAP and RF. Cardiac enzyme assessments, chest radiography, electrocardiography, and echocardiography were performed at the admission date and 2 weeks after admission. t-test and chi-square test were used for comparison between first and second investigations, and the statistically significance level was a P <0.05.ResultsOf the 135 patients, pericardial effusion occurred in 80 (59%), valvular regurgitation in 30 (22%), ST/T changes in 66 (49%), cardiac arrhythmia in 7 (5%), and myocardial injury in 83 (62%). Significant improvement of cardiothoracic-ratio, heart rate, ST/T changes, cardiac arrhythmia, troponin T, myocardial performance, and left-ventricular ejection fraction was demonstrated at second investigations. Three mortality cases exhibited evidence of congestive heart failure (CHF).ConclusionChildren with CAP and RF had several cardiac effects even in healthy children. Most cardiac effects were mild and transient. Mortality cases were revealed evidence of congestive heart failure (CHF). Future research should be designed to find out the characteristics and predictors of CHF for early recognition and therapeutic strategy.

Cardiac involvement in children with community-acquired pneumonia and respiratory failure

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

BackgroundPneumonia causes significant incidence in children younger than 5 years. Most fatalities are resulted from complications. High rates of cardiac...

Cardiac involvement in children with community-acquired pneumonia and respiratory failure

Article Category: Brief communication (original)

Publicado en línea: 10 sept 2020

Páginas: 119 - 124

DOI: https://doi.org/10.1515/abm-2020-0018

Palabras clave
cardiac effects, myocardial injury, pericardial effusion pneumonia, respiratory failure

© 2020 Kachaporn Nimdet et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Cardiac involvement in children with community-acquired pneumonia and respiratory failure

Article Category: Brief communication (original)

Publicado en línea: 10 sept 2020

Páginas: 119 - 124

DOI: https://doi.org/10.1515/abm-2020-0018

Palabras clavecardiac effects, myocardial injury, pericardial effusion pneumonia, respiratory failure

© 2020 Kachaporn Nimdet et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Palabras clave
cardiac effects, myocardial injury, pericardial effusion pneumonia, respiratory failure