<abstract><title style='display:none'>Summary</title>According to the World Health Organization there are almost two billion people worldwide who consume alcohol on a regular basis. It’s a common abuse and almost 80 million are diagnozed with “alcohol abuse disorders” (WHO 2002, 2004). Excessive alcohol consumption is related to more than 60 different medical conditions, as suicide, homicide and different forms of accidents. Some conditions are acute, while other conditions such as liver cirrhosis, chronic pancreatitis, haemorrhagic stroke and various forms of cancer, are chronic consequences. Non-carious destructions of teeth like dental erosion are also associated with frequent alcohol consumption, because of precipitation of salivary proline-rich proteins caused by polyphenols present in most alcoholic drinks. The high concentration of organic and inorganic acids and the habit of keeping the alcoholic drink in the mouth can cause chronic inflammations of the soft tissues in the mouth and can increase the negative side effects from metals of crowns, bridges, orthodontic devises and various restorations. A literature review has been made due to the authors clinical observations and experiences.</abstract>

Conservative Dentistry, FDM, MU – Sofia, Faculty of Dental Medicine Medical University 1 Sv. G. Sofi yski St. BG – 1431 Sofia

Conservative Dentistry, FDM, MU – Sofia

Effect of Alcohol to Oral Health

<abstract><title style='display:none'>Abstract</title>This study attempted to determine the level of psychological well-being among postgraduate students. The study also aimed to assess the relationship between psychological well-being and demographic factors, such as age and field of study. Psychological well-being questionnaires were administered to a sample of 192 Master of Education students. The findings demonstrated that Master of Education students possessed a slightly high level of psychological well-being. Differences were found in students’ psychological well-being across age groups, F (4, 167) = 3.178, p = 0.01, and field of study, F (8, 163) = 2.668, p = 0.01, respectively. According to the results, students in the age group of 41 years and above possessed the highest level of psychological well-being (M = 5, SD = 0.71).</abstract>

Psychological Well-being among Postgraduate Students

<abstract>
<title style='display:none'>Abstract</title>
<sec>
<title style='display:none'>Aims</title>
The aims of the present study are to investigate the relationship between the anthropometric indicators and peculiarities of the nutritional intake in people with overweight and obesity and the risk factors for the development of dental caries in adults.
</sec>
<sec>
<title style='display:none'>Materials and Methods</title>
The study involved 264 individuals aged between 18 and 60 years. The following risk factors for the development of dental caries were traced: diet (carbohydrate intake), oral hygiene habits and social status in overweight and obese people. The dental caries incidence was determined through the DMFT index, by assessing the total number of teeth which are decayed (D), missing (M) due to caries, or filled (treated, F).
</sec>
<sec>
<title style='display:none'>Results</title>
The age-related distribution was as follows: from 18 to 25 years – 14.4%; from 25 to 35 years – 16.7%; from 35 to 50 years – 42.4%; and over 50 years – 26.5%. The established average BMI was 25.60 ± 4.359, with the lowest and highest measured values – 18.5 and 37.55, respectively. The value of DMFT was 12.55 ± 5.545. A direct correlation between the elevated incidence of dental caries in patients with overweight and obesity was revealed. No significant relationship was found between the decreased nutritional intake of vitamin D and the incidence of dental caries in individuals with Class I and Class II obesity.
</sec>
<sec>
<title style='display:none'>Conclusion</title>
Dental caries and obesity have a similar etiology – improper dietary habits, excessive consumption of foods containing low molecular weight carbohydrates and carbonated beverages. The reported higher levels of dental caries in these groups could be explained by an improper diet and more frequent snacking.
</sec>
</abstract>

Dietary Intake of Vitamin D and Dental Caries Incidence in People with Overweight and Obesity

<abstract><title style='display:none'>Abstract</title>The pulp hyperaemia is associated with increased blood flow in the pulp. Diagnosis of this condition is very important for the outcome of a dental treatment. There are new methods, which can detect the pulp blood flow. Such method, gaining increasing popularity nowadays, is pulse oximetry. In this study, intact teeth and teeth with diagnosis of hyperaemia pulpae are examined by pulse oximeter and electric pulp test. The results show that the threshold of irritation is decreased in teeth with hyperemia, and the saturation of the pulp is increased by 12.34% in frontal teeth and 7.27% in distal teeth. There is a statistically significant difference (p &lt; 0,05) in the values measured with pulse oximeter in the intact frontal and distal teeth and the teeth with hyperemia. Pulse oximetry can detect changes in pulp microcirculation in state of hyperemia. It is an extremely valuable method for early, objective diagnosis of pulp blood flow, as well as for its monitoring in dynamics.</abstract>

Pulse Oximetry and Electric Pulp Test in Intact Teeth and Teeth with Hyperaemia Pulpae

<abstract>
<title style='display:none'>Abstract</title>
<sec>
<title style='display:none'>Introduction</title>
Liver resection is widely accepted as a treatment option for primary liver cancer and metastases. The goal of surgery is to resect all tumours with negative histological margins while preserving sufficient functional hepatic parenchyma and reducing postoperative complications. The use of Indocyanine green (ICG) for liver function assessment and fluorescence image-guided surgery could be used to achieve that goal.
</sec>
<sec>
<title style='display:none'>Clinical Case Description</title>
We present the case of a 62-year-old female patient with diagnosed sigmoid colon cancer with four bilobar liver metastases who underwent a simultaneous sigmoid resection and ICG fluorescence image-guided liver resection 3 days after preoperative ICG liver function assessment. We decided to perform liver-sparing resection having in mind the liver metastases’ number, size and location and the slightly impaired liver function (ICG retention rate 15 – ICGR15 was 14,02%). All liver tumours were removed without complications, and the resected margins were all microscopically free of tumour tissue (R0 resection). The postoperative period was uneventful, without any signs of postoperative liver failure.
</sec>
<sec>
<title style='display:none'>Conclusions</title>
ICGR15 can be considered a safe and informative marker for liver function and indirectly for the degree of portal hypertension. ICG fluorescence provides an additional method to assist intra-operative tumour identification. The best timing of injection requires further study.
</sec>
</abstract>

Indocyanine Green Fluorescence for Liver Assessment and Imaging-Guided Resection of Colorectal Metastases: A Case Report

<abstract>
<title style='display:none'>Abstract</title>
<sec>
<title style='display:none'>Objective</title>
The aim of the present prospective clinical study was to highlight the importance of the proper application of the manual detorsion (MD) in cases of intravaginal testicular torsion. Major complications such as ischemia, reperfusion injury and testicular compartment syndrome could be avoided.
</sec>
<sec>
<title style='display:none'>Materials and Methods</title>
From January 2017 to February 2018, 26 boys aged between 8 and 16 years underwent surgical treatment for intravaginal testicular torsion (ITT) (14 left- and 12 right-sided). Diagnosis was made upon clinical criteria (both symptoms and signs); sudden onset of scrotal pain (n = 26, 100%), nausea and vomiting (n = 25, 96,15%), abdominal pain (n = 3, 11,53%), high testicular position (n = 21, 80,77%), absence of the cremasteric reflex (n = 26, 100%), harshness of the twisted testicle (TT) (n = 24, 87.5%), alteration on axis or orientation of the TT (n = 24, 94,31%), and pain during palpation (n = 26, 100%). Two cases presented with neglected scrotum leading to inability to evaluate the intrascrotal structures. Major ultrasonographic findings were the following: absence of perfusion, heterogeneity of the parenchyma and identification of the Whirlpool sign. Therefore, our study group consisted of 15 out of the 26 cases, in which the initial assessment at the Emergency Department occurred within the first 3-7 hours after the onset of ITT.
</sec>
<sec>
<title style='display:none'>Results</title>
Based on high clinical suspicion and ultrasonographic documentation of the ITT, MD was performed in all those cases. Pain alleviation followed immediately, while significant improvement of the clinical picture of the suffering scrotum was also observed. Successful detorsion was documented via ultrasonography. After completion of the preoperative assessment, bilateral orchidopexy was performed. All patients had an uneventful postoperative course and were discharged home on the second postoperative day.
</sec>
<sec>
<title style='display:none'>Conclusion</title>
In conclusion, we hereby document that MD is a safe, non-invasive method, easy to learn for every clinician. It can be applied immediately after the diagnosis of the ITT, converting a highly urgent surgery into an elective one. Of course, surgical exploration of intrascrotal structures constitutes a crucial final step.
</sec>
</abstract>

The Importance of Manual Detorsion in Intravaginal Testicular Torsion

<abstract>
<title style='display:none'>Abstract</title>
<sec><title style='display:none'>Background</title>
Cushing's Syndrome (CS) is the consequence of the exposure of tissues to extremely high levels of glucocorticoids. Early diagnosis and treatment are the mainstay of optimizing patient outcomes and improving their quality of life. In the recent years steroid profiling by LC-MS sheds more light on the diagnosis of CS.
</sec>
<sec><title style='display:none'>Materials and methods</title>
This was a retrospective cross-sectional study.
</sec>
<sec><title style='display:none'>Objective</title>
To investigate serum steroid precursor differences between different etiological forms of CS and to suggest a steroid panel for the diagnosis of MACS in patients with adrenal incidentalomas.
</sec>
<sec><title style='display:none'>Results</title>
Our studied patients with CD had significantly lower levels of 11-deoxycorticosterone (p = 0.047) and 17 OH progesterone (p = 0.024) compared to those with adrenal forms of CS. In out cohort of patients with adrenal incidentalomas, those with MACS had significantly lower levels of androgens (DHEA, p = 0.001) and cortisone (p = 0.015) and higher levels of 11-deoxycortisol (p = 0.039) compared to the patients with non-secreting adenomas (NSA). 
</sec>
<sec><title style='display:none'>Conclusion</title>
Introducing LC-MS based steroid profiling would be very helpful in the diagnostic process of patients with CS.
</sec>
</abstract>

Steroid Profiling in the Differential Diagnosis of Cushing's Syndrome and Diagnosis of MACS

<abstract>
<title style='display:none'>Abstract</title>
The last decades were characterized by rapid progress in the introduction of new digital technologies in the field of prosthetics. The intraoral scanning systems are data acquisition devices which make it possible to make precise prosthetic structures, to identify carious lesions, Orthodontic anomalies. This article analyzes modern trends in the field of newly developed intraoral scanning technologies published in scientific journals in recent years. It summarizes the information provided by various databases: PubMed, Research-Gate, Google Scholar and on the internet sites of manufacturing companies. As a result, a historical review was made with a focus on the development of intraoral scanning systems and their characteristics, advantages and disadvantages were thoroughly discussed.
</abstract>

The Modern Digital Intraoral Scanning Systems: A Review

<abstract>
<title style='display:none'>Abstract</title>
<sec><title style='display:none'>Background</title>
The purpose of the study was to investigate the correlation between the results of 4 cognitive tests and years of parental education and to analyze their impact on cognitive performance in mentally healthy subjects.
</sec>
<sec><title style='display:none'>Subjects and Methods</title>
The sample consisted of 72 mentally healthy subjects (25 men, 47 women) assessed by 4 cognitive tests – the Trail Making Test A (TMT-A), the Trail Making Test Β (TMT-B), Digit Symbol Test (DST) and Verbal Fluency Test (VFT). Results were analyzed with descriptive statistics, Pearson correlation analysis and the partial correlation method to control the influence of one factor on the correlation between two variables.
</sec>
<sec><title style='display:none'>Results</title>
More years of parental education were associated with higher cognitive results. All four tests showed that mother's years of education have stronger positive influence on the cognitive performance of the child than fathers's years of education. For mothers this positive influential correlation have reached statistical significance for two cognitive tests – TMT-A (p &lt; .000) and TMT-B (p &lt; .007) and for DST was dose to reaching statistical significance (p &lt;. 103), while for fathers only TMT-A has showed a statistically significant correlation. These general patterns of tendencies of parental education as a factor correlated to cognitive performance in offspring are retained even after Controlling for subject's age or years of education, which independently have strong correlations with the results of the 4 cognitive tests.
</sec>
<sec><title style='display:none'>Conclusions</title>
Mother's years of education affect cognitive functions of the offspring much more than father's years of education.
</sec>
</abstract>

Parental Education as a Factor Correlated to Cognitive Performance in Offspring

<abstract>
<title style='display:none'>Abstract</title>
Except the widely accepted use of immune Checkpoint inhibitors in the treatment of microsatellite instability-high (MSI-H) mismatch repair-deficient (MMRd) CRCs representing about 5% of all metastatic (m)CRC patients, new strategies are applied to cure MMR-proficient (MMRp) mCRC patients. Tumor microenvironment (TME) is decisive for cancer development. The determination of some immunoeffective and immunosuppressive immune cells and some cytokines, chemokines and growth factors in the TME gives Information about the use of immune Checkpoint inhibitors in MMRp CRCs. The increased level of IL-6 in the serum and increased number of IL-6+ immune cells in TME, the increased number of IL-17+ Th17 cells, and of FoxP3+ cells are used to determine the use of anti-IL-6 antibody and of anti-FoxP3 antibody for treatment. The determination of high CD8+, high PD-1 expression and little or no Th17 cells appoint better response to anti-PD-1 therapy. The used combination therapies are: combination of immunotherapy with chemotherapy, with radiation therapy, with targeted therapy, with vaccines, oncolytic viruses and bispeeifie antibodies. Classical treatment of CRC patients has included chemotherapy, radiotherapy and surgery. Recently, immunotherapy has been added as a mainstay for therapy of CRC. The main checkpoint inhibitors used in CRC immunotherapy are pembrolizumab and nivolumab (anti-PD-1), durvalumab (anti-PD-L1), ipilimumab (anti-CTLA-4), favezelimab (anti-LAG3), etc. They are applied after fluorapyrimidine, oxaliplain, and irinotecan therapy. In conclusion, we may state that the future treatment of MSS CRC is in combination therapies, i.e. conventional and immunotherapies. We consider that immune infiltrate in TME must be assessed in order to determine combination therapies.
</abstract>

New approach in Understanding Colorectal Cancer Immunosuppression and Immunotherapy-Based Strategies in the Treatment of Microsatellite Stable Colorectal Cancer

<abstract>
<title style='display:none'>Abstract</title>
Science has emerged as a powerful tool to facilitate researchers in conducting trustful summary of achievements in clinical practice. Science has a leading role in modern medicine as it allows prediction of the future development of new scientific ideas, formulating the prospects for future development. The purpose of the article was to make a comparative analysis and evaluation of the allocated funds for scientific and teaching staff hired under second employment contract in the university clinics or accredited teaching hospitals or departments for clinical training of the Medical University – Sofia for the period 2013-2022, and to show the effectiveness of investing in human capital. For the purposes of the research, the following were used: documentary method, analysis and synthesis and comparative method. During the analyzed period, a permanent tendency towards a decrease in the total number of clinical teachers in all clinical training centres was observed. The total amount of funds spent on the wage fund for the ten-year period increased by 35.7% compared to the beginning of the period. The increase in the funds for the salary fund of the clinical teachers stems from the policy that was introduced in 2016 with the Collective Labor Agreement – together with the social partners stimulation (bonus) for theoretical and practical training of medical students both in the Bulgarian language (state order), as well as payment for English language training. With a view to improving the quality of education of future healthcare Professionals, MU – Sofia continuously invests its own funds in its scientific and teaching staff. Proof of the effectiveness of the invested funds are the results of the last 10 years of the Rating System of the higher schools in the Republic of Bulgaria, in which MU – Sofia was ranked first in the five professional areas in which it conducts training.
</abstract>

Investments in Scientific Teaching Staff – Main Determinant of Quality Medical Education

<abstract>
<title style='display:none'>Abstract</title>
<sec><title style='display:none'>Introduction</title>
Metabolic syndrome (MS) is often associated with anxiety and depression. Chaenomeles japonica (Thunb.) Lindl, also known as Chaenomeles maulei or Japanese quince, is a medicinal plant with a long history of use forits health-promoting properties.
</sec>
<sec><title style='display:none'>Aim</title>
The aim of this study was to investigate the effects of Japanese quince fruit juice (JQFJ) administration on locomotor activity, anxiety and depressive behavior in rats with diet-induced MS.
</sec>
<sec><title style='display:none'>Materials and methods</title>
Forty adult male Wistar rats were divided into 4 groups: MS, MS+JQFJ2.5, MS+JQFJ5 and MS+JQFJ10. All groups received a high-fat high-fructose diet for the induction of MS. MS animals were daily orally treated with distilled water and the other groups with JQFJ at doses of 2.5 ml/kg, 5 ml/kg and 10 ml/kg, respectively. During the 10th week of the experiment, behavioral tests were carried out.
</sec>
<sec><title style='display:none'>Results</title>
In the open Held test, no effect of JQFJ treatment on locomotor activity was observed. In the elevated plus maze test, a dose-dependent increase in the time spent in the open arms (OA) of the apparatus and in the ratio time spent in OA vs. total time spent in any of the arms was interpreted as an anxiolytic effect. The immobility time in the forced swim test did not differ significantly among the groups, which demonstrated a lack of anti-depressant action.
</sec>
<sec><title style='display:none'>Conclusions</title>
Chronic Japanese quince fruit juice administration produced a dose-dependent anxiolytic-like effect in rats with diet-induced MS, probably due to its high content of polyphenols.
</sec>
</abstract>

Behavioral Effects of Chronic Japanese Quince Fruit Juice Administration to Rats with Diet-Induced Metabolic Syndrome

<abstract><title style='display:none'>Summary</title>Biological rhythm of sleeping is a natural disparity in an organism corresponding to and in reply to cyclic environmental changes, such as daylight hours and hours of darkness or elevated and low down flow. There is some evidence, based upon epidemiological studies as well as studies upon smaller groups of subjects, that individuals who work during the night and sleep during the daytime show cognitive impairment at work, have poorer and fragmented daytime sleep, and have increased risks of developing a wide range of social, psychological, physiological and medical impairments and disorders. Circadian rhythms are one of the most important effective factors on the physiological and physical performances of humans and disturbing this normal rhythm leads to different groups of diseases. The majority of investigations in biological rhythm demeanor vary noticeably in regards to the exact type of disease, population and protocols of sampling over the other outcomes or issues. We conducted a systematic review of [Science Direct, Pubmed, Scopus] to identify influence of different kinds of diseases among shift workers in response to abnormal rhythm of sleeping. The results of this review indicate that abnormal patterns of sleeping can lead to immunological issues, hypertension, metabolic syndrome, insomnia, cardiovascular disease, obesity and depression. It is vital for subsequent investigations to find a way to reduce negative effects (such as decreased amount of works’ time and altered diet) without side effects to help them.</abstract>

Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, University Putra Malaysia

Faculty of Physical Education and Sport Science, Shahid Bahonar University of Kerman, Kerman, Iran

Faculty of Educational Studies, Department of Sport Sciences, University Putra Malaysia, Malaysia

The Adverse Health Effects of Shift Work in Relation to Risk of Illness/Disease: A Review

<abstract><title style='display:none'>Summary</title>There are a variety of body aches that fall under the umbrella term of Musculoskeletal Discomforts (MSDs). These can be distinguished based on the level of pain suffered by the patient, ranging from mild and sporadic to serious, constant and fatal. It has been suggested that a link exists between MSDs and risk factors involving one’s occupational conditions and physicality. Examining the prevalence rate of musculoskeletal discomforts based on the severity among office workers was the main objective of this study. In order to achieve this objective, we had, in February 2015, selected from a population of 20 000 Malaysian office workers, 753 subjects within the age range of 20-50 years who have had a minimum of a year’s working experience. For this study, a form of structured questionnaire, known as the Cornell questionnaire, has been evaluated and put to use. Under the watch of the researchers, the subjects were instructed to complete the questionnaire in the morning before they begin their respective jobs. Based on their responses, the Cornell questionnaire has revealed that at least one case of severe pain in the neck, shoulder or lower back, respectively, is suffered by 69.7% of the subjects. In the case of neck-related aches, 15% low pain, whereas 51% involved mild pain and 33.9% were cases of severe pain. That being said, 19.3% low pain in the lower back, while 50.7% suffered from mild pain and 30% had severe pain in the same region. Percentages of 34.9% for high severity, 45.4% for mild severity and 19.7% for low severity were simultaneously reported in the shoulder section. In a nutshell, the study has revealed that, in comparison with body aches in the arms, knees, upper back, forearms, wrists, hands, hips and thighs, the subjects are more vulnerable to body aches in the neck, shoulders and lower back. </abstract>

Department of Occupational Health, Faculty of Medicine and Health Sciences, University Putra Malaysia, Malaysia

Department of Orthopedics, Faculty of Medicine and Health Sciences, University Putra Malaysia, Malaysia

University for the Enhancement of Academic Performance, University of Malaya, Malaysia

Department of Pathology, Faculty of Medicine and Health Sciences, University Putra Malaysia, Malaysia

Prevalence Rate of Musculoskeletal Discomforts Based on Severity Level Among Office Workers

<abstract><title style='display:none'>Summary</title>Wound reparative process after surgery, burns, injuries, and inflammatory processes results in a spectrum of scar formation ranging from nearly scarless healing to excessive fibrosis or atrophy. Scarring is considered a major medical problem that leads to aesthetic and functional sequelae. Scar tissue is clinically distinguished from normal skin by an aberrant color, rough surface texture, increased thickness (hypertrophy), occurrence of contraction, and firmness. In the last decade, the concept of wound healing kinetics has been developed to describe the delicate balance of cell activity involved in scar formation and remodeling. Hypertrophic scars and keloids are formed as a result of the process of abnormal wound healing. Despite all that has been written on improving the appearance of these types of scars, there are no definitive management protocols. The aim of the present article is to make a brief review of the basic wound healing, while focusing on medicine’s latest understanding of the development and treatment of keloids and hypertrophic scars.</abstract>

Unit of Plastic Surgery and Burns, Military Medical Academy, Sofia

Department of Dermatovenereology and Allergology, Military Medical Academy, Sofia

Hypertrophic Scars and Keloids – Contemporary Concepts and Treatment Options

<abstract><title style='display:none'>Abstract</title>Cotinus coggygria Scop. leaf aqueous ethanolic extract was examined for its in vitro antiproliferative and antioxidant activity. Antiproliferative effect was assessed on four human gynecological cancer cell lines: breast (MCF7, T47D), cervical (HeLa) and ovarian (A2780) and compared to the cell growth inhibitory effect on non-cancerous breast epithelial cell line MCF10A using MTT cell proliferation assay. Radical scavenging assay with DPPH was applied to evaluate antioxidant potential of the extract. The obtained results showed that the herb inhibited cell growth of all of the tested cancer cell lines and the highest was the cytostatic effect on A2780 cells with a half maximal inhibitory concentration (IC50) value of 30.8 μg/ml. For the other cell lines the IC50 values were in the range of 55-122.7 μg/ml. Additionally, the extract exerted considerably weaker reduction in cell proliferation of the non-cancerous cell line MCF10A compared to cancer cells, which indicates for antiproliferative selectivity. C. coggygria extract showed high free radical scavenging activity with an IC50 value of 11.2 μg/ml. The obtained data provide evidence for pharmacological potential of the tested extract and future more detailed studies concerning the molecular mechanisms of the anticancer effect of the herb are needed.</abstract>

Antiproliferative Properties Against Human Breast, Cervical and Ovarian Cancer Cell Lines, and Antioxidant Capacity of Leaf Aqueous Ethanolic Extract from <italic>Cotinus coggygria</italic> Scop.

<abstract><title style='display:none'>Abstract</title>Available antiepileptic drugs interact with a variety of different molecular targets. The mechanism of action of most anticonvulsants is most often complex with a number of affected regions. The combination of mechanisms of action of drugs in particular proportions can possibly determine the showcase of its antiepileptic activity. The common factor between the different supposed mechanisms for a number of drugs includes the possibility for modulating the excitatory and inhibitory neurotransmission through effects upon the voltage-gated ion channels, synaptic plasticity, heterogeneous receptors, and metabolism of neurotransmitters. There are controversial data on the extent to which a specific action can be the reason for the wholesome anticonvulsive characteristics of various medications, as well as the relation with the presence of undesired drug effects. The complexity of the action of some antiepileptic drugs creates conditions for optimal choice during therapy. In many cases, the insufficient familiarity with individual genetic differences and the disease related receptor damages can hinder defining a particular drug action. Characterizing the mechanisms of action of the present antiepileptic medications would increase the understanding for the pathophysiological mechanisms of epileptic seizures, as well as the development of new therapeutic strategies. The development of novel antiepileptic drugs and the ongoing research regarding the mechanism of action of established antiepileptic drugs, are continuously increasing the level of complexity in the spectrum of molecular targets relevant for epilepsy therapy. The current state of knowledge as well as the limitations in our understanding should guide future research aiming for a more detailed elucidation of the impact of genetics and pathophysiological mechanisms on interindividual differences in expression and function of antiepileptic drug targets.</abstract>

Basic Mechanisms of Action of the Antiepileptic Drugs

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Acta Medica Bulgarica

pISSN: 0324-1750, eISSN: 2719-5384  Aim &amp; Scope  The Journal Acta Medica Bulgarica (AMB), published continuously since 1973, is...

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pISSN: 0324-1750, eISSN: 2719-5384  Aim &amp; Scope  The Journal Acta Medica Bulgarica...