<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Anaemia is one of the most common symptoms accompanying many chronic diseases, e.g. collagenases, neoplasms, and chronic inflammations (inflammatory bowel disease, chronic kidney disease and heart failure). Iron deficiency anaemia is the most common type of anaemia (80%). It affects 1% to 2% of the population. Iron deficiency (ID) – absolute or functional – is characterised by reduced ferritin levels and transferrin saturation (TSAT) of less than 20%. Iron deficiency is the most common dietary deficiency. However, iron deficiency might be one of the common causes of anaemia of chronic disease (ACD). Anaemia affects 33% to 60% of patients with RA. Rheumatoid arthritis (RA) is a chronic immune-mediated systemic connective tissue disease, in which chronic inflammation of the synovial tissue of the joints damages articular cartilages, bones and other joint structures. The prevalence of RA is approximately 0.3% to 2%. Low haemoglobin levels in RA patients are significantly correlated with disability, activity and duration of the disease as well as damage to joints and joint pain. Treatment of anaemia in RA patients includes iron supplementation, blood transfusions, the use of erythropoiesis-stimulating agents, and treatment of the underlying condition. Biological treatments used in RA patients, such as e.g. infliximab, tocilizumab and anakinra, not only slow the progression of joint involvement but also prevent anaemia.</p>
</abstract>

Anaemia is one of the most common symptoms accompanying many chronic diseases, e.g. collagenases, neoplasms, and chronic inflammations (inflammatory bowel disease, chronic kidney disease and heart failure). Iron deficiency anaemia is the most common type of anaemia (80%). It affects 1% to 2% of the population. Iron deficiency (ID) – absolute or functional – is characterised by reduced ferritin levels and transferrin saturation (TSAT) of less than 20%. Iron deficiency is the most common dietary deficiency. However, iron deficiency might be one of the common causes of anaemia of chronic disease (ACD). Anaemia affects 33% to 60% of patients with RA. Rheumatoid arthritis (RA) is a chronic immune-mediated systemic connective tissue disease, in which chronic inflammation of the synovial tissue of the joints damages articular cartilages, bones and other joint structures. The prevalence of RA is approximately 0.3% to 2%. Low haemoglobin levels in RA patients are significantly correlated with disability, activity and duration of the disease as well as damage to joints and joint pain. Treatment of anaemia in RA patients includes iron supplementation, blood transfusions, the use of erythropoiesis-stimulating agents, and treatment of the underlying condition. Biological treatments used in RA patients, such as e.g. infliximab, tocilizumab and anakinra, not only slow the progression of joint involvement but also prevent anaemia.

Anaemia and iron deficiency in patients with rheumatoid arthritis and other chronic diseases<xref ref-type="fn" rid="j_01.3001.0014.7838_fn_001"><sup>*</sup></xref>

Department of Internal Medicine, 4th Military Teaching Hospital

Division of Oncology and Palliative Care, Department of Clinical Nursing, Faculty of Health Science

Dept of Surgery, 4th Military Teaching Hospital

Division of Nursing in Internal Medicine, Department of Clinical Nursing, Faculty of Health Science

Postępy Higieny i Medycyny Doświadczalnej

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Anaemia and iron deficiency in patients with rheumatoid arthritis and other chronic diseases

Niedokrwistość i niedobór żelaza u chorych na reumatoidalne zapalenie stawów i inne choroby przewlekłe

Anaemia is one of the most common symptoms accompanying many chronic diseases, e.g. collagenases, neoplasms, and chronic inflammations (inflammatory bowel...

Anaemia and iron deficiency in patients with rheumatoid arthritis and other chronic diseases^*

Article Category: Review

Online veröffentlicht: 02. März 2021

Seitenbereich: 143 - 151

Eingereicht: 21. Apr. 2020

Akzeptiert: 19. Okt. 2020

DOI: https://doi.org/10.5604/01.3001.0014.7838

Schlüsselwörter
iron management, rheumatoid arthritis, iron deficiency anaemia, biological agents

© 2021 Wojciech Tański et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Anaemia and iron deficiency in patients with rheumatoid arthritis and other chronic diseases*

Article Category: Review

Online veröffentlicht: 02. März 2021

Seitenbereich: 143 - 151

Eingereicht: 21. Apr. 2020

Akzeptiert: 19. Okt. 2020

DOI: https://doi.org/10.5604/01.3001.0014.7838

Schlüsselwörteriron management, rheumatoid arthritis, iron deficiency anaemia, biological agents

© 2021 Wojciech Tański et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Anaemia and iron deficiency in patients with rheumatoid arthritis and other chronic diseases^*

Schlüsselwörter
iron management, rheumatoid arthritis, iron deficiency anaemia, biological agents