<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_1905-7415.0905.431_s_001_w2aab3b7b3b1b6b1aab1c17b1Aa"><h3>Background</h3><p>Not all morphological lung changes in the elderly contribute to respiratory disease and may be a consequence of normal aging.</p></sec><sec id="j_1905-7415.0905.431_s_002_w2aab3b7b3b1b6b1aab1c17b2Aa"><h3>Objectives</h3><p>To describe the changes in asymptomatic elderly patients compared with those in younger patients in a Thai population.</p></sec><sec id="j_1905-7415.0905.431_s_003_w2aab3b7b3b1b6b1aab1c17b3Aa"><h3>Methods</h3><p>The study cohort comprised 60 participants without respiratory symptoms in three groups of 20 by age: 20-40 years, 41-60 years, and >60 years. Participants were prospectively selected from patients referred for computed tomography (CT) of the abdomen, or head and neck, and underwent sequential CT during deep breathing at four lung levels. Two observers scored images by consensus. We compared groups using Pearson chi-square and Fisher exact tests, and used receiver operating characteristic curves to categorize bronchiectasis and bronchial wall thickening by age.</p></sec><sec id="j_1905-7415.0905.431_s_004_w2aab3b7b3b1b6b1aab1c17b4Aa"><h3>Results</h3><p>Air trapping was related to age (5/20 group 1, 7/20 group 2, and 18/20 group 3 (<italic>P</italic> &lt;0.01)) and was most prevalent in lower lobes (78%, <italic>P</italic> &lt; 0.01). Reticulation was found in only one middle aged patient (<italic>P</italic> = 0.36). Bronchiectasis was more common in patients &lt;56 years (7/23) than &lt;56 years (3/37), <italic>P</italic> = 0.035. Bronchial wall thickening (7/23 in patients >56 years and 2/37 in patients &lt;56 years, <italic>P</italic> = 0.02) and extensive air trapping were related to age (0/6 group 1, 1/6 group 2, and 5/6 group 3, <italic>P</italic> = 0.02). Findings were independent of smoking history.</p></sec><sec id="j_1905-7415.0905.431_s_005_w2aab3b7b3b1b6b1aab1c17b5Aa"><h3>Conclusions</h3><p>Asymptomatic older patients had higher prevalence of bronchiectasis, bronchial wall thickening, and air trapping, independent of smoking history.</p></sec></abstract>

BackgroundNot all morphological lung changes in the elderly contribute to respiratory disease and may be a consequence of normal aging.ObjectivesTo describe the changes in asymptomatic elderly patients compared with those in younger patients in a Thai population.MethodsThe study cohort comprised 60 participants without respiratory symptoms in three groups of 20 by age: 20-40 years, 41-60 years, and >60 years. Participants were prospectively selected from patients referred for computed tomography (CT) of the abdomen, or head and neck, and underwent sequential CT during deep breathing at four lung levels. Two observers scored images by consensus. We compared groups using Pearson chi-square and Fisher exact tests, and used receiver operating characteristic curves to categorize bronchiectasis and bronchial wall thickening by age.ResultsAir trapping was related to age (5/20 group 1, 7/20 group 2, and 18/20 group 3 (P <0.01)) and was most prevalent in lower lobes (78%, P < 0.01). Reticulation was found in only one middle aged patient (P = 0.36). Bronchiectasis was more common in patients <56 years (7/23) than <56 years (3/37), P = 0.035. Bronchial wall thickening (7/23 in patients >56 years and 2/37 in patients <56 years, P = 0.02) and extensive air trapping were related to age (0/6 group 1, 1/6 group 2, and 5/6 group 3, P = 0.02). Findings were independent of smoking history.ConclusionsAsymptomatic older patients had higher prevalence of bronchiectasis, bronchial wall thickening, and air trapping, independent of smoking history.

CT features of normal lung change in asymptomatic elderly patients

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"CT features of normal lung change in asymptomatic elderly patients"}

BackgroundNot all morphological lung changes in the elderly contribute to respiratory disease and may be a consequence of normal aging.ObjectivesTo describe the changes in asymptomatic elderly patients compared with those in younger patients in a Thai population.MethodsThe study cohort comprised 60 participants without respiratory symptoms in three groups of 20 by age: 20-40 years, 41-60 years, and >60 years. Participants were prospectively selected from patients referred for computed tomography (CT) of the abdomen, or head and neck, and underwent sequential CT during deep breathing at four lung levels. Two observers scored images by consensus. We compared groups using Pearson chi-square and Fisher exact tests, and used receiver operating characteristic curves to categorize bronchiectasis and bronchial wall thickening by age.ResultsAir trapping was related to age (5/20 group 1, 7/20 group 2, and 18/20 group 3 (P 56 years and 2/37 in patients <56 years, P = 0.02) and extensive air trapping were related to age (0/6 group 1, 1/6 group 2, and 5/6 group 3, P = 0.02). Findings were independent of smoking history.ConclusionsAsymptomatic older patients had higher prevalence of bronchiectasis, bronchial wall thickening, and air trapping, independent of smoking history.

BackgroundNot all morphological lung changes in the elderly contribute to respiratory disease and may be a consequence of normal aging.ObjectivesTo describe...

CT features of normal lung change in asymptomatic elderly patients

Article Category: Brief communication (Original)

Online veröffentlicht: 31. Jan. 2017

Seitenbereich: 613 - 623

DOI: https://doi.org/10.5372/1905-7415.0905.431

Schlüsselwörter
Aging lung, asymptomatic, CT, reticulation, senile lung

© 2015 Nattinee Leelakanok, Nitra Piyavisetpat

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

CT features of normal lung change in asymptomatic elderly patients

Article Category: Brief communication (Original)

Online veröffentlicht: 31. Jan. 2017

Seitenbereich: 613 - 623

DOI: https://doi.org/10.5372/1905-7415.0905.431

SchlüsselwörterAging lung, asymptomatic, CT, reticulation, senile lung

© 2015 Nattinee Leelakanok, Nitra Piyavisetpat

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
Aging lung, asymptomatic, CT, reticulation, senile lung