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Trend Analysis of Fungal Infections Based on Culture among Inpatients in Henan Province from 2018 to 2023

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16. Sept. 2025

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Fig. 1.

Distribution of fungal species among infectious disease patients.
Distribution of fungal species among infectious disease patients.

Fig. 2.

Distribution of Candida albicans among infectious disease patients in different months.
Distribution of Candida albicans among infectious disease patients in different months.

Fig. 3.

Distribution of Aspergillus flavus among infectious disease patients in different months.
Distribution of Aspergillus flavus among infectious disease patients in different months.

Fig.4.

Distribution of Aspergillus fumigatus among infectious disease patients in different months.
Distribution of Aspergillus fumigatus among infectious disease patients in different months.

Fig. 5.

Detection rates of influenza and COVID-19 in throat swab samples (tested by PCR).
Detection rates of influenza and COVID-19 in throat swab samples (tested by PCR).

Fungal detection rates in hospitalized patients in different departments [n (%)]_

Species AIDS Department (N = 9,113) Tuberculosis Department (N = 22,494) Hepatology Department (N = 9,068) ICU (N = 2,963) Other Departments (N = 31,364)
n (%) n (%) n (%) n (%) n (%)
Aspergillus fumigatus 154 (1.69) 159 (0.71) 13 (0.15) 65 (2.18) 50 (0.16)
Aspergillus flavus 100 (1.10) 162 (0.72) 10 (0.11) 69 (2.33) 33 (0.10)
Aspergillus niger 30 (0.33) 49 (0.22) 6 (0.06) 14 (0.46) 4 (0.01)
Candida albicans 1,286 (14.11) 462 (2.05) 21 (0.23) 282 (9.53) 288 (0.92)
Candida glabrata 93 (1.02) 94 (0.42) 1 (0.01) 52 (1.75) 50 (0.16)
Candida parapsilosis 18 (0.19) 16 (0.07) 2 (0.02) 16 (0.52) 18 (0.06)
Candida tropicalis 126 (1.38) 111 (0.49) 8 (0.09) 81 (2.75) 57 (0.18)
Talaromyces marneffei 141 (1.54) 5 (0.02) 3 (0.03) 33 (1.10) 12 (0.04)
Cryptococcus neoformans 166 (1.82) 19 (0.08) 0 (0.00) 41 (1.40) 2 (0.01)
Fungal positivity 1,755 (19.26) 992 (4.41) 64 (0.71) 564 (19.04) 445 (1.42)

Fungal detection rates in rural and urban patients [n (%)]_

Species Rural (N = 28,359) Urban (N = 46,642) χ2 p
n (%) n (%)
Aspergillus fumigatus 231 (0.82) 210 (0.45) 1.23 0.27
Aspergillus flavus 208 (0.73) 166 (0.36) 8.93 < 0.01
Aspergillus niger 52 (0.18) 52 (0.11) 0.00 1.00
Candida albicans 1,264 (4.46) 1,075 (2.31) 234.12 < 0.01
Candida glabrata 147 (0.52) 143 (0.31) 0.11 0.74
Candida parapsilosis 31 (0.11) 39 (0.08) 1.24 0.27
Candida tropicalis 180 (0.63) 203 (0.44) 2.06 0.15
Talaromyces marneffei 123 (0.43) 71 (0.15) 13.97 < 0.01
Cryptococcus neoformans 132 (0.47) 96 (0.21) 5.99 0.01
Fungal positivity 1,927 (6.80) 1,623 (3.48) 429.89 < 0.001

The main specimen sources and corresponding fungal isolates [n (%)]_

Fungal species Sputum Lavage fluid Blood Cerebrospinal fluid, pleural fluid, ascites, etc. (other sterile body fluids) Swabs, urine, feces, etc. (other non-sterile specimens)
n (%) n (%) n (%) n (%) n (%)
Aspergillus fumigatus 299 (63.48) 159 (33.76) 0 (0.00) 0 (0.00) 13 (2.76)
Aspergillus flavus 244 (55.96) 188 (43.12) 0 (0.00) 0 (0.00) 4 (0.92)
Aspergillus niger 75 (63.03) 0 (0.00) 31 (26.05) 4 (3.36) 9 (7.56)
Candida albicans 798 (33.13) 66 (2.74) 159 (6.60) 50 (2.08) 1,336 (55.46)
Candida glabrata 103 (33.88) 16 (5.26) 18 (5.92) 23 (7.57) 144 (47.37)
Candida parapsilosis 10 (13.16) 6 (7.89) 7 (9.21) 4 (5.26) 49 (64.47)
Candida tropicalis 37 (64.91) 0 (0.00) 0 (0.00) 0 (0.00) 20 (35.09)
Talaromyces marneffei 22 (8.89) 11 (5.45) 133 (65.84) 21 (12.40) 15 (7.43)
Cryptococcus neoformans 2 (0.81) 4 (1.61) 85 (34.27) 157 (63.31) 0 (0.00)
Sprache:
Englisch
Zeitrahmen der Veröffentlichung:
4 Hefte pro Jahr
Fachgebiete der Zeitschrift:
Biologie, Mikrobiologie und Virologie