<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Few pieces of research have focused on <italic>Micrococcus luteus</italic> bloodstream infection (BSI) because of its low incidence; hence data is needed to illustrate this uncommon infection. This study aimed to explore the clinical characteristics of patients with <italic>M. luteus</italic> BSI. From January 2010 to December 2019, inpatients that met the criteria for <italic>M. luteus</italic> BSI were included in this study. Data was collected by reviewing electronic records. Ninety-seven patients were enrolled in this study. Sixty-three percent of the patients have a higher neutrophil percentage (NEUT%). The average blood C-reactive protein (CRP) concentration was 5.5 ± 6.4 mg/dl. 48.5% of the patients had malignancy, and 40.2% underwent invasive surgeries. Linezolid was found to have the largest average diameter of the inhibition zone (36 mm), while erythromycin was found to have the smallest average zone diameter (15 mm). However, some <italic>M. luteus</italic> strains had a potentially broad antimicrobial resistance spectrum. Cephalosporins (59.2%) and quinolones (21.4%) were the most commonly used antibiotics for empirical therapies. In conclusion, <italic>M. luteus</italic> BSI mainly happens in immunocompromised patients or those with former invasive surgeries or indwelling catheters. <italic>M. luteus</italic> strains are less responsive to erythromycin. Cephalosporins and quinolones are effective empirical antibiotics for <italic>M. luteus</italic> BSI; however, vancomycin and teicoplanin should be considered for potentially broadly drug-resistant <italic>M. luteus</italic> strains.<fig id="j_pjm-2021-030_fig_001" position="float" fig-type="figure"><graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/j_pjm-2021-030_fig_001.jpg"></graphic></fig></p></abstract>

Few pieces of research have focused on Micrococcus luteus bloodstream infection (BSI) because of its low incidence; hence data is needed to illustrate this uncommon infection. This study aimed to explore the clinical characteristics of patients with M. luteus BSI. From January 2010 to December 2019, inpatients that met the criteria for M. luteus BSI were included in this study. Data was collected by reviewing electronic records. Ninety-seven patients were enrolled in this study. Sixty-three percent of the patients have a higher neutrophil percentage (NEUT%). The average blood C-reactive protein (CRP) concentration was 5.5 ± 6.4 mg/dl. 48.5% of the patients had malignancy, and 40.2% underwent invasive surgeries. Linezolid was found to have the largest average diameter of the inhibition zone (36 mm), while erythromycin was found to have the smallest average zone diameter (15 mm). However, some M. luteus strains had a potentially broad antimicrobial resistance spectrum. Cephalosporins (59.2%) and quinolones (21.4%) were the most commonly used antibiotics for empirical therapies. In conclusion, M. luteus BSI mainly happens in immunocompromised patients or those with former invasive surgeries or indwelling catheters. M. luteus strains are less responsive to erythromycin. Cephalosporins and quinolones are effective empirical antibiotics for M. luteus BSI; however, vancomycin and teicoplanin should be considered for potentially broadly drug-resistant M. luteus strains.

Clinical Characteristics of Patients with <italic>Micrococcus luteus</italic> Bloodstream Infection in a Chinese Tertiary-Care Hospital

Polish Journal of Microbiology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Clinical Characteristics of Patients with  Bloodstream Infection in a Chinese Tertiary-Care Hospital

Few pieces of research have focused on Micrococcus luteus bloodstream infection (BSI) because of its low incidence; hence data is needed to illustrate this...

Clinical Characteristics of Patients with Micrococcus luteus Bloodstream Infection in a Chinese Tertiary-Care Hospital

Article Category: original-paper

Online veröffentlicht: 17. Sept. 2021

Seitenbereich: 321 - 326

Eingereicht: 19. Apr. 2021

Akzeptiert: 12. Juli 2021

DOI: https://doi.org/10.33073/pjm-2021-030

Schlüsselwörter
antimicrobial resistance, bloodstream infection, clinical characteristics,

© 2021 Minghui Zhu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Clinical Characteristics of Patients with Micrococcus luteus Bloodstream Infection in a Chinese Tertiary-Care Hospital

Article Category: original-paper

Online veröffentlicht: 17. Sept. 2021

Seitenbereich: 321 - 326

Eingereicht: 19. Apr. 2021

Akzeptiert: 12. Juli 2021

DOI: https://doi.org/10.33073/pjm-2021-030

Schlüsselwörterantimicrobial resistance, bloodstream infection, clinical characteristics,

© 2021 Minghui Zhu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Schlüsselwörter
antimicrobial resistance, bloodstream infection, clinical characteristics,