Tigecycline For Skin Infection With SIRS In Immunocompromised Host

Tigecycline is the first agent in the new class of glycylcycline antibiotics.

It’s expanded broad spectrum of activity, with demonstrated efficacy as monotherapy against clinically important Gram-positive and Gram-negative pathogens include also anerobes and antibiotic-resistant isolates.

It is presented the case of a 54 years old man, recently diagnosed with HIV infection, that had high fever and skin abscesses. The laboratory investigations showed a Systemic Inflammatory Response Syndrome.

After 10 days of treatment with Tygacil, 100 mg at first, then 50 mg/12 hours, surgical incision and drainage, antiinflammatory and symptomatic treatment, the patient’s symptoms disappeared and we started also the antiretroviral therapy.