<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Hemophilia A (HA) is a hereditary, life-threatening and disabling disorder. In this study, we have examined 61 unrelated HA patients in order to identify the incidence of the intron 1 factor VIII (FVIII) gene inversion in the West Anatolian population. According to the results of DNA analyses of the 61 HA patients, no intron 1 inversion of the FVIII gene was found.</p></abstract>

Hemophilia A (HA) is a hereditary, life-threatening and disabling disorder. In this study, we have examined 61 unrelated HA patients in order to identify the incidence of the intron 1 factor VIII (FVIII) gene inversion in the West Anatolian population. According to the results of DNA analyses of the 61 HA patients, no intron 1 inversion of the FVIII gene was found.

Factor VIII-Intron 1 Inversion of Hemophilia A Patients In West Anatolia

Department of Internal Medicine, Haematology Division, Gaziantep University, Gaziantep, Turkey

Department of Medical Biology and Genetics, Gaziantep University, Gaziantep, Turkey

Genetic Diseases Research and Application Centre, Ege University, Izmir, Turkey

Department of Internal Medicine, Haematology Division, Ege University, Izmir, Turkey

Department of Paediatrics, Haematology Division, Ege University, Izmir, Turkey

Balkan Journal of Medical Genetics

{"article-title":"Factor VIII-Intron 1 Inversion of Hemophilia A Patients In West Anatolia"}

Hemophilia A (HA) is a hereditary, life-threatening and disabling disorder. In this study, we have examined 61 unrelated HA patients in order to identify the...

Factor VIII-Intron 1 Inversion of Hemophilia A Patients In West Anatolia

Online veröffentlicht: 10. Okt. 2007

Seitenbereich: 49 - 50

DOI: https://doi.org/10.2478/v10034-007-0009-2

Schlüsselwörter
Hemophilia, Factor VIII (FVIII), Intron 1 inversion, DNA, Polymerase chain reaction (PCR)

This content is open access.

Factor VIII-Intron 1 Inversion of Hemophilia A Patients In West Anatolia

Online veröffentlicht: 10. Okt. 2007

Seitenbereich: 49 - 50

DOI: https://doi.org/10.2478/v10034-007-0009-2

SchlüsselwörterHemophilia, Factor VIII (FVIII), Intron 1 inversion, DNA, Polymerase chain reaction (PCR)

This content is open access.

Schlüsselwörter
Hemophilia, Factor VIII (FVIII), Intron 1 inversion, DNA, Polymerase chain reaction (PCR)