Zitieren

Draganov DI, La Du BN. Pharmacogenetics of paraoxonases: a brief review. Naunyn-Schmiedeberg's Arch Pharmacol 2004;369:78-88.10.1007/s00210-003-0833-1Search in Google Scholar

Lusis AJ. Atherosclerosis. Nature 2000;407:233-41.10.1038/35025203Search in Google Scholar

Shih DM, Gu L, Xia YR, Navab M, Li WF, Hama S, Castellani LW, Furlong CE, Costa LG, Fogelman AM, Lusis AJ. Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis. Nature 1998;394:284-7.10.1038/28406Search in Google Scholar

Mackness MI, Arrol S, Durrington PN. Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein. Fed Eur Biochem Soc Lett 1991;286:152-4.10.1016/0014-5793(91)80962-3Search in Google Scholar

Reddy ST, Wadleigh DJ, Grijalva V, Ng C, Hama S, Gangopadhyay A, Shih DM, Lusis AJ, Navab M, Fogelman AM. Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids. Arterioscler Thromb Vasc Biol 2001;21:542-7.10.1161/01.ATV.21.4.542Search in Google Scholar

Rodrigo L, Mackness B, Durrington PN, Hernandez A, Mackness MI. Hydrolysis of platelet-activating factor by human serum paraoxonase. Biochem J 2001;354:1-7.10.1042/bj3540001Search in Google Scholar

Ahmed Z, Ravandi A, Maguire GF, Emili A, Draganov D, La Du BN, Kuksis A, Connelly PW. Apolipoprotein A-I promotes the formation of phosphatidylcholine core aldehydes that are hydrolyzed by paraoxonase (PON-1) during high density lipoprotein oxidation with a peroxynitrite donor. J Biol Chem 2001;276:24473-81.10.1074/jbc.M010459200Search in Google Scholar

Jakubowski H. Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation. J Biol Chem 2000;275:3957-62.10.1074/jbc.275.6.3957Search in Google Scholar

Lund-Katz S, Liu L, Thuahnai ST, Phillips MC. High density lipoprotein structure. Front Biosci 2003;8: d1044-54.10.2741/1077Search in Google Scholar

Fuhrman B, Volkova N, Aviram M. Oxidative stress increases the expression of the CD36 scavenger receptor and the cellular uptake of oxidized low-density lipoprotein in macrophages from atherosclerotic mice: protective role of antioxidants and of paraoxonase. Atherosclerosis 2002;161:307-16.10.1016/S0021-9150(01)00646-3Search in Google Scholar

Rozenberg O, Shih DM, Aviram M. Human serum paraoxonase 1 decreases macrophage cholesterol biosynthesis: possible role for its phospholipase-A2-like activity and lysophosphatidylcholine formation. Arterioscler Thromb Vasc Biol 2003;23:461-7.10.1161/01.ATV.0000060462.35946.B3Search in Google Scholar

Sorenson RC, Bisgaier CL, Aviram M, Hsu C, Billecke S, La Du BN. Human serum Paraoxonase/Arylesterase's retained hydrophobic N-terminal leader sequence associates with HDLs by binding phospholipids: apolipoprotein A-I stabilizes activity. Arterioscler Thromb Vasc Biol 1999;19:2214-25.10.1161/01.ATV.19.9.2214Search in Google Scholar

Aharoni A, Gaidukov L, Yagur S, Toker L, Silman I, Tawfik DS. Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization. Proc Natl Acad Sci USA 2004;101:482-7.10.1073/pnas.2536901100Search in Google Scholar

Harel M, Aharoni A, Gaidukov L, Brumshtein B, Khersonsky O, Meged R, Dvir H, Ravelli RB, McCarthy A, Toker L, Silman I, Sussman JL, Tawfik DS. Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes. Nat Struct Mol Biol 2004;11:412-9.10.1038/nsmb767Search in Google Scholar

Morales R, Berna A, Carpentier P, Contreras-Martel C, Renault F, Nicodeme M, Chesne-Seck ML, Bernier F, Dupuy J, Schaeffer C, Diemer H, Van-Dorsselaer A, Fontecilla-Camps JC, Masson P, Rochu D, Chabriere E. Discovery and crystallographic structure of human apolipoprotein. Ann Pharm 2000;65:98-107.10.1016/S0003-4509(07)90023-1Search in Google Scholar

Josse D, Ebel C, Stroebel D, Fontaine A, Borges F, Echalier A, Baud D, Renault F, Le Maire M, Chabriere E, Masson P. Oligomeric states of the detergent-solubilized human serum paraoxonase (PON1). J Biol Chem 2002;277:33386-97.10.1074/jbc.M20010820012080042Search in Google Scholar

Rosenblat M, Gaidukov L, Khersonsky O, Vaya J, Oren R, Tawfik DS, Aviram M. The catalytic His dyad of High Density Lipoprotein-associated serum paraoxonase-I (PON1) is essential for PON1-mediated inhibition of Low Density Lipoprotein oxidation and stimulation of macrophage cholesterol efflux. J Biol Chem 2006;281:7657-66.10.1074/jbc.M51259520016407304Search in Google Scholar

Khersonsky O, Tawfik DS. The histidine-115 histidine-134 dyad mediates the lactonase activity of mammalian serum paraoxonases. J Biol Chem 2006;281:7649-56.10.1074/jbc.M51259420016407305Search in Google Scholar

Kuo CL, La Du BN. Comparison of purified human and rabbit serum paraoxonases. Drug Metab Dispos 1995;23:935-44.Search in Google Scholar

Roodveldt C, Aharoni A, Tawfik DS. Directed evolution of proteins for heterologous expression and stability. Curr Opin Struct Biol 2005;15:50-6.10.1016/j.sbi.2005.01.00115718133Search in Google Scholar

Sekar K, Yu BZ, Rogers J, Lutton J, Liu X, Chen X, Tsai MD, Jain MK, Sundaralingam M. Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-99. Biochemistry 1997;36:3104-14.10.1021/bi961576x9115986Search in Google Scholar

Scharff EI, Koepke J, Fritzsch G, Lucke C, Ruterjans H. Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris. Structure (Camb) 2001;9:493-502.10.1016/S0969-2126(01)00610-4Search in Google Scholar

Waldo GS. Genetic screens and directed evolution for protein solubility. Curr Opin Chem Biol 2003;7:33-8.10.1016/S1367-5931(02)00017-0Search in Google Scholar

Roodveldt C, Tawfik DS. Directed evolution of phosphotriesterase from Pseudomonas diminuta for heterologous expression in Escherichia coli results in stabilization of the metal-free state. Protein Eng Des Sel 2005;18:51-583.10.1093/protein/gzi00515790580Search in Google Scholar

ISSN:
0004-1254
Sprachen:
Englisch, Slovenian
Zeitrahmen der Veröffentlichung:
4 Hefte pro Jahr
Fachgebiete der Zeitschrift:
Medizin, Vorklinische Medizin, Grundlagenmedizin, andere