The Prevalence of Self-Reported Systemic Allergic Reaction to Hymenoptera Venom in Beekeepers Worldwide: A Systematic Literature Review and Meta-Analysis
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Aguiar AP, Deans AR, Engel MS, Forshage M, Huber JT, Jennings JT, et al. Order Hymenoptera. In: Zhang Z-Q, editor. Animal biodiversity: An outline of higher-level classification and survey of taxonomic richness (Addenda 2013). USA: Magnolia Press; 2013. p. 51–62.AguiarAPDeansAREngelMSForshageMHuberJTJenningsJTOrder HymenopteraIn:ZhangZ-QeditorAnimal biodiversity: An outline of higher-level classification and survey of taxonomic richness (Addenda 2013)USAMagnolia Press20135162Search in Google Scholar
Malec P, Weber J, Böhmer R, Fiebig M, Meinert D, Rein C, et al. The emergence of ecotypes in a parasitoid wasp: A case of incipient sympatric speciation in Hymenoptera? BMC Ecol Evol. 2021;21(1):2–22. doi: 10.1186/s12862-021-01938-y.MalecPWeberJBöhmerRFiebigMMeinertDReinCThe emergence of ecotypes in a parasitoid wasp: A case of incipient sympatric speciation in Hymenoptera?BMC Ecol Evol.202121122210.1186/s12862-021-01938-yOpen DOISearch in Google Scholar
Blaimer BB, Santos BF, Cruaud A, Gates MW, Kula RR, Miko I, et al. Key innovations and the diversification of Hymenoptera. Nat Commun. 2023;14(1):1–18. doi: 10.1038/s41467-023-36868-4.BlaimerBBSantosBFCruaudAGatesMWKulaRRMikoIKey innovations and the diversification of HymenopteraNat Commun.202314111810.1038/s41467-023-36868-4Open DOISearch in Google Scholar
Müller UR. Insect venoms. Chem Immunol Allergy. 2010;95:141–156. doi: 10.1159/000315948.MüllerURInsect venomsChem Immunol Allergy.20109514115610.1159/000315948Open DOISearch in Google Scholar
Golden DBK. Anaphylaxis to insect stings. Immunol Allergy Clin North Am. 2015;35(2):287–302. doi: 10.1016/j.iac.2015.01.007.GoldenDBKAnaphylaxis to insect stingsImmunol Allergy Clin North Am.201535228730210.1016/j.iac.2015.01.007Open DOISearch in Google Scholar
Bilò MB, Pravettoni V, Bignardi D, Bonadonna P, Mauro M, Novembre E, et al. Hymenoptera venom allergy: Management of children and adults in clinical practice. J Investig Allergol Clin Immunol. 2019;29(3):180–205. doi: 10.18176/jiaci.0310.BilòMBPravettoniVBignardiDBonadonnaPMauroMNovembreEHymenoptera venom allergy: Management of children and adults in clinical practiceJ Investig Allergol Clin Immunol.201929318020510.18176/jiaci.0310Open DOISearch in Google Scholar
Blank S, Haemmerle S, Jaeger T, Russkamp D, Ring J, Schmidt-Weber CB, et al. Prevalence of Hymenoptera venom allergy and sensitization in the population-representative German KORA cohort. Allergo J Int. 2019;28:183–191. doi: 10.1007/s40629-018-0089-4.BlankSHaemmerleSJaegerTRusskampDRingJSchmidt-WeberCBPrevalence of Hymenoptera venom allergy and sensitization in the population-representative German KORA cohortAllergo J Int.20192818319110.1007/s40629-018-0089-4Open DOISearch in Google Scholar
Bilò MB, Tontini C, Martini M, Corsi A, Agolini S, Antonicelli L. Clinical aspects of hymenoptera venom allergy and venom immunotherapy. Eur Ann Allergy Clin Immunol. 2019;51(6):244–258. doi: 10.23822/EurAnnACI.1764-1489.113.BilòMBTontiniCMartiniMCorsiAAgoliniSAntonicelliLClinical aspects of hymenoptera venom allergy and venom immunotherapyEur Ann Allergy Clin Immunol.201951624425810.23822/EurAnnACI.1764-1489.113Open DOISearch in Google Scholar
Tankersley MS, Ledford DK. Stinging insect allergy: State of the art 2015. J Allergy Clin Immunol Pract. 2015;3(3):315–322. doi: 10.1016/j.jaip.2015.03.012.TankersleyMSLedfordDKStinging insect allergy: State of the art 2015J Allergy Clin Immunol Pract.20153331532210.1016/j.jaip.2015.03.012Open DOISearch in Google Scholar
Müller UR. Bee venom allergy in beekeepers and their family members. Curr Opin Allergy Clin Immunol. 2005;5(4):343–347. doi: 10.1097/01.all.0000173783.42906.95.MüllerURBee venom allergy in beekeepers and their family membersCurr Opin Allergy Clin Immunol.20055434334710.1097/01.all.0000173783.42906.95Open DOISearch in Google Scholar
Stanhope J, Carver S, Weinstein P. Health outcomes of beekeeping: A systematic review. J Apic Res. 2017;56(2):100–111. doi: 10.1080/00218839.2017.1291208.StanhopeJCarverSWeinsteinPHealth outcomes of beekeeping: A systematic reviewJ Apic Res.201756210011110.1080/00218839.2017.1291208Open DOISearch in Google Scholar
Bilò MB, Bonifazi F. The natural history and epidemiology of insect venom allergy: Clinical implications. Clin Exp Allergy. 2009;39(10):1467–1476. doi: 10.1111/j.1365-2222.2009.03324.x.BilòMBBonifaziFThe natural history and epidemiology of insect venom allergy: Clinical implicationsClin Exp Allergy.200939101467147610.1111/j.1365-2222.2009.03324.xOpen DOISearch in Google Scholar
Nittner-Marszalska M, Liebhart J, Liebhart E, Dor A, Dobek R, Obojski A, et al. Prevalence of Hymenoptera venom allergy and its immunological markers current in adults in Poland. Med Sci Monit. 2004;10(7):CR324–329.Nittner-MarszalskaMLiebhartJLiebhartEDorADobekRObojskiAPrevalence of Hymenoptera venom allergy and its immunological markers current in adults in PolandMed Sci Monit.2004107CR324329Search in Google Scholar
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ. 2021;372(71):1–9. doi:10.1136/bmj.n71.PageMJMcKenzieJEBossuytPMBoutronIHoffmannTCMulrowCDThe PRISMA 2020 statement: An updated guideline for reporting systematic reviewsBMJ.2021372711910.1136/bmj.n71Open DOISearch in Google Scholar
Carli T, Locatelli I, Košnik M, Kukec A. Epidemiology and risk factors of self-reported systemic allergic reactions to a Hymenoptera venom in beekeepers worldwide: A protocol for a systematic review of observational studies. BMJ Open. 2022;12(7):1–5. doi: 10.1136/bmjopen-2021-058130.CarliTLocatelliIKošnikMKukecAEpidemiology and risk factors of self-reported systemic allergic reactions to a Hymenoptera venom in beekeepers worldwide: A protocol for a systematic review of observational studiesBMJ Open.20221271510.1136/bmjopen-2021-058130Open DOISearch in Google Scholar
Munn Z, Moola S, Lisy K, Riitano D, Tufanaru C. Methodological guidance for systematic reviews of observational epidemiological studies reporting prevalence and incidence data. Int J Evid Based Healthc. 2015;13(3):147–153. doi: 10.1097/XEB.0000000000000054.MunnZMoolaSLisyKRiitanoDTufanaruCMethodological guidance for systematic reviews of observational epidemiological studies reporting prevalence and incidence dataInt J Evid Based Healthc.201513314715310.1097/XEB.0000000000000054Open DOISearch in Google Scholar
Annila IT, Karjalainen ES, Annila PA, Kuusisto PA. Bee and wasp sting reactions in current beekeepers. Ann Allergy Asthma Immunol. 1996;77(5):423–427. doi: 10.1016/S1081-1206(10)63342-X.AnnilaITKarjalainenESAnnilaPAKuusistoPABee and wasp sting reactions in current beekeepersAnn Allergy Asthma Immunol.199677542342710.1016/S1081-1206(10)63342-XOpen DOISearch in Google Scholar
Celikel S, Karakaya G, Yurtsever N, Sorkun K, Kalyoncu AF. Bee and bee products allergy in Turkish beekeepers: Determination of risk factors for systemic reactions. Allergol Immunopathol (Madr). 2006;34(5):180–184. doi: 10.1157/13094024.CelikelSKarakayaGYurtseverNSorkunKKalyoncuAFBee and bee products allergy in Turkish beekeepers: Determination of risk factors for systemic reactionsAllergol Immunopathol (Madr).200634518018410.1157/13094024Open DOISearch in Google Scholar
Münstedt K, Hellner M, Winter D, von Georgi R. Allergy to bee venom in beekeepers in Germany. J Investig Allergol Clin Immunol. 2008;18(2):100–105.MünstedtKHellnerMWinterDvon GeorgiRAllergy to bee venom in beekeepers in GermanyJ Investig Allergol Clin Immunol.2008182100105Search in Google Scholar
Richter AG, Nightingale P, Huissoon AP, Krishna MT. Risk factors for systemic reactions to a bee venom in British beekeepers. Ann Allergy Asthma Immunol. 2011;106(2):159–163. doi: 10.1016/j.anai.2010.11.005.RichterAGNightingalePHuissoonAPKrishnaMTRisk factors for systemic reactions to a bee venom in British beekeepersAnn Allergy Asthma Immunol.2011106215916310.1016/j.anai.2010.11.005Open DOISearch in Google Scholar
Becerril-Ángeles M, Nuñez-Velázquez M, Grupo del Programa de Control de la Abeja Africanizada, SAGARPA. [Risk factors for allergy to honey-bee venom in Mexican beekeepers]. Rev Alerg Mex. 2013;60(3):100–104.Becerril-ÁngelesMNuñez-VelázquezMGrupo del Programa de Control de la Abeja Africanizada, SAGARPA[Risk factors for allergy to honey-bee venom in Mexican beekeepers]Rev Alerg Mex.2013603100104Search in Google Scholar
Çelıksoy MH, Sancak R, Söğüt A, Güner SN, Korkmaz A. Characteristics of venom allergic reactions in Turkish beekeepers and alternative treatment modalities. Int Forum Allergy Rhinol. 2014;4(7):555–558. doi:10.1002/alr.21314.ÇelıksoyMHSancakRSöğütAGünerSNKorkmazACharacteristics of venom allergic reactions in Turkish beekeepers and alternative treatment modalitiesInt Forum Allergy Rhinol.20144755555810.1002/alr.21314Open DOISearch in Google Scholar
Ediger D, Terzioglu K, Ozturk RT. Venom allergy, risk factors for systemic reactions and the knowledge levels among Turkish beekeepers. Asia Pac Allergy. 2018.11;8(2):1–6. doi: 10.5415/apallergy.2018.8.e15.EdigerDTerziogluKOzturkRTVenom allergy, risk factors for systemic reactions and the knowledge levels among Turkish beekeepersAsia Pac Allergy.201811821610.5415/apallergy.2018.8.e15Open DOISearch in Google Scholar
Demirkale ZH, Yücel E, Çimen SS, Süleyman A, Özdemir C, A Kara, et al. Venom allergy and knowledge about anaphylaxis among beekeepers and their families. Allergol Immunopathol (Madr). 2020;48(6):640–645. doi: 10.1016/j.aller.2020.01.008.DemirkaleZHYücelEÇimenSSSüleymanAÖzdemirCKaraAVenom allergy and knowledge about anaphylaxis among beekeepers and their familiesAllergol Immunopathol (Madr).202048664064510.1016/j.aller.2020.01.008Open DOISearch in Google Scholar
Antonicelli L, Bilò MB, Bonifazi F. Epidemiology of Hymenoptera allery. Curr Opin Allergy Clin Immunol. 2002;2(4):341–346. doi: 10.1097/00130832-200208000-00008.AntonicelliLBilòMBBonifaziFEpidemiology of Hymenoptera alleryCurr Opin Allergy Clin Immunol.20022434134610.1097/00130832-200208000-00008Open DOISearch in Google Scholar
Bilò MB, Bonifazi F. Epidemiology of insect-venom anaphylaxis. Curr Opin Allergy Clin Immunol. 2008;8(4):330–337. doi: 10.1097/ACI.0b013e32830638c5.BilòMBBonifaziFEpidemiology of insect-venom anaphylaxisCurr Opin Allergy Clin Immunol.20088433033710.1097/ACI.0b013e32830638c5Open DOISearch in Google Scholar
Košnik M, Korošec P. Hymenoptera-induced hypersensitivity reactions and anaphylaxis. In: Castells MC, editor. Anaphylaxis and Hypersensitivity Reactions. 1st ed. USA: Humana Press; 2010. p. 209– 222.KošnikMKorošecPHymenoptera-induced hypersensitivity reactions and anaphylaxisIn:CastellsMCeditorAnaphylaxis and Hypersensitivity Reactions1st edUSAHumana Press2010209222Search in Google Scholar
Alsharawy A, Spoon R, Smith A, Ball S. Gender differences in fear and risk perception during the COVID-19 pandemic. Front Psychol. 2021:12(689467):1–9. doi: 10.3389/fpsyg.2021.689467.AlsharawyASpoonRSmithABallSGender differences in fear and risk perception during the COVID-19 pandemicFront Psychol.2021126894671910.3389/fpsyg.2021.689467Open DOISearch in Google Scholar
Anagnostou A, Lieberman J, Greenhawt M, Mack DP, Santos AF, Venter C, et al. The future of food allergy: Challenging existing paradigms of clinical practice. Allergy. 2023;78(7):1847–1865. doi: 10.1111/all.15757.AnagnostouALiebermanJGreenhawtMMackDPSantosAFVenterCThe future of food allergy: Challenging existing paradigms of clinical practiceAllergy.20237871847186510.1111/all.15757Open DOISearch in Google Scholar
Cichocka-Jarosz E. Hymenoptera venom allergy in humans. Folia Med Cracov. 2012;52(3–4):43–60.Cichocka-JaroszEHymenoptera venom allergy in humansFolia Med Cracov.2012523–44360Search in Google Scholar
Bousquet J, Ménardo JL, Aznar R, Robinet-Lévy M, Michel FB. Clinical and immunologic survey in beekeepers in relation to their sensitization. J Allergy Clin Immunol. 1984;73(3):332–340. doi: 10.1016/0091-6749(84)90405-6.BousquetJMénardoJLAznarRRobinet-LévyMMichelFBClinical and immunologic survey in beekeepers in relation to their sensitizationJ Allergy Clin Immunol.198473333234010.1016/0091-6749(84)90405-6Open DOISearch in Google Scholar
Contreras-Escareño F, Echazarreta CM, Pérez-Armendáriz B, Cavazos AJ, Macías-Macías JO, Tapia-González JM. Beekeeping in Jalisco, México. In: Chambó ED, editor. Beekeeping and bee conservation - advances in research. InTechOpen; 2016. p. 252.Contreras-EscareñoFEchazarretaCMPérez-ArmendárizBCavazosAJMacías-MacíasJOTapia-GonzálezJMBeekeeping in Jalisco, MéxicoIn:ChambóEDeditorBeekeeping and bee conservation - advances in researchInTechOpen2016252Search in Google Scholar
Jee CJ, Morato-Castro FF, Palma MS, Malaspina O, Neto RSA, Costa-Manso E, et al. Acquired immunity to Africanized honeybee (Apis mellifera) venom in Brazilian beekeepers. J Investig Allergol Clin Immunol. 1997;7(6):583–587.JeeCJMorato-CastroFFPalmaMSMalaspinaONetoRSACosta-MansoEAcquired immunity to Africanized honeybee (Apis mellifera) venom in Brazilian beekeepersJ Investig Allergol Clin Immunol.199776583587Search in Google Scholar
Blank S, Grosch J, Ollert M, Bilò MB. Precision medicine in hymenoptera venom allergy: Diagnostics, biomarkers, and therapy of different endotypes and phenotypes. Front Immunol. 2020;11(579409):1–17. doi: 10.3389/fimmu.2020.579409.BlankSGroschJOllertMBilòMBPrecision medicine in hymenoptera venom allergy: Diagnostics, biomarkers, and therapy of different endotypes and phenotypesFront Immunol.20201157940911710.3389/fimmu.2020.579409Open DOISearch in Google Scholar
Pucci S, De Pasquale T, D’Alò S,Illuminati I, Makrì E, Incorvaia C. Systemic reactions to honeybee stings and nonsteroidal antinflammatory drugs. Ann Allergy Asthma Immunol. 2014;113(2):237–238. doi: 10.1016/j.anai.2014.06.001.PucciSDe PasqualeTD’AlòSIlluminatiIMakrìEIncorvaiaCSystemic reactions to honeybee stings and nonsteroidal antinflammatory drugsAnn Allergy Asthma Immunol.2014113223723810.1016/j.anai.2014.06.001Open DOISearch in Google Scholar
Rijavec M, Inkret J, Bidovec-Stojković U, Carli T, Frelih N, Kukec A, et al. Fatal Hymenoptera venom–triggered anaphylaxis in patients with unrecognized clonal mast cell disorder. Is the mastocytosis to blame? Int J Mol Sci. 2023;24(22):1–9. doi: 10.3390/ijms242216368.RijavecMInkretJBidovec-StojkovićUCarliTFrelihNKukecAFatal Hymenoptera venom–triggered anaphylaxis in patients with unrecognized clonal mast cell disorder. Is the mastocytosis to blame?Int J Mol Sci.202324221910.3390/ijms242216368Open DOISearch in Google Scholar
Eich-Wanger C, Müller UR. Bee sting allergy in beekeepers. Clin Exp Allergy. 1998;28(10):1292–1298. doi: 10.1046/j.1365-2222.1998.00411.x.Eich-WangerCMüllerURBee sting allergy in beekeepersClin Exp Allergy.199828101292129810.1046/j.1365-2222.1998.00411.xOpen DOISearch in Google Scholar
Turillazzi S, Turillazzi F. Climate changes and Hymenoptera venom allergy: Are there some connections? Curr Opin Allergy Clin Immunol. 2017;17(5):344–349. doi: 10.1097/ACI.0000000000000388.TurillazziSTurillazziFClimate changes and Hymenoptera venom allergy: Are there some connections?Curr Opin Allergy Clin Immunol.201717534434910.1097/ACI.0000000000000388Open DOISearch in Google Scholar