<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Hypertension presents one of the main risk factors for cardiovascular diseases which are the leading cause of morbidity and mortality worldwide. Structural and mechanical changes of the heart and blood vessels as well as overproduction of reactive oxygen species may occur due to the increased blood pressure. Therewith, the goal of our study was to estimate the effects and duration of swimming as a possible therapy approach on blood pressure and oxidative stress parameters in normotensive and hypertensive rats. The study was conducted on 60 male Wistar albino rats divided into two groups, normotensive and hypertensive rats. Each of these groups was divided into three subgroups according to the swimming protocol. The swimming training was kept constant (60 min/day, for five days a week) with two days of rest. After six or nine weeks of the swimming protocol, blood pressure and oxidative stress markers were measured. The control group rats were put in water for one minute a day, in order to avoid water-induced stress. Training significantly reduced systolic blood pressure in hypertensive rats, while diastolic pressure did not change in the group that swam six or nine weeks. The results showed that swimming increases the activity of all measured antioxidative parameters, while values of prooxidants varied depending on the training protocol. Our results confirmed that swimming, as an aerobic exercise, decreases blood pressure and has time-dependent positive system adaptations, especially on the antioxidant parameters.</p>
</abstract>

Hypertension presents one of the main risk factors for cardiovascular diseases which are the leading cause of morbidity and mortality worldwide. Structural and mechanical changes of the heart and blood vessels as well as overproduction of reactive oxygen species may occur due to the increased blood pressure. Therewith, the goal of our study was to estimate the effects and duration of swimming as a possible therapy approach on blood pressure and oxidative stress parameters in normotensive and hypertensive rats. The study was conducted on 60 male Wistar albino rats divided into two groups, normotensive and hypertensive rats. Each of these groups was divided into three subgroups according to the swimming protocol. The swimming training was kept constant (60 min/day, for five days a week) with two days of rest. After six or nine weeks of the swimming protocol, blood pressure and oxidative stress markers were measured. The control group rats were put in water for one minute a day, in order to avoid water-induced stress. Training significantly reduced systolic blood pressure in hypertensive rats, while diastolic pressure did not change in the group that swam six or nine weeks. The results showed that swimming increases the activity of all measured antioxidative parameters, while values of prooxidants varied depending on the training protocol. Our results confirmed that swimming, as an aerobic exercise, decreases blood pressure and has time-dependent positive system adaptations, especially on the antioxidant parameters.

Swimming Attenuates Blood Pressure and Oxidative Stress in Hypertensive Rats

University of Kragujevac, Faculty of Medical Sciences

1st Moscow State Medical University I.M. Sechenov

University of Kosovska Mitrovica, Faculty of Sport and Physical Education

Experimental and Applied Biomedical Research (EABR)

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Swimming Attenuates Blood Pressure and Oxidative Stress in Hypertensive Rats"}

Hypertension presents one of the main risk factors for cardiovascular diseases which are the leading cause of morbidity and mortality worldwide. Structural and...

Swimming Attenuates Blood Pressure and Oxidative Stress in Hypertensive Rats

Online veröffentlicht: 20. Juni 2023

Seitenbereich: 107 - 114

Eingereicht: 13. Jan. 2020

Akzeptiert: 26. Jan. 2020

DOI: https://doi.org/10.2478/sjecr-2020-0006

Schlüsselwörter
Antioxidant protection, hypertension, oxidative stress, rats, swimming

© 2023 Anica Petkovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Swimming Attenuates Blood Pressure and Oxidative Stress in Hypertensive Rats

Online veröffentlicht: 20. Juni 2023

Seitenbereich: 107 - 114

Eingereicht: 13. Jan. 2020

Akzeptiert: 26. Jan. 2020

DOI: https://doi.org/10.2478/sjecr-2020-0006

SchlüsselwörterAntioxidant protection, hypertension, oxidative stress, rats, swimming

© 2023 Anica Petkovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Schlüsselwörter
Antioxidant protection, hypertension, oxidative stress, rats, swimming