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A Study of Absorption and Selected Molecular Physicochemical Properties of Some Antipsychotic Drugs

   | 14. Okt. 2022

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1. Ritter J.M., Flower R.J., Henderson G., Loke Y.K., MacEwan D., Rang H.P. (2019). Rang and Dale’s Farmacology, 98th ed., Elsevier, Churchill Livingstone. Search in Google Scholar

2. Moffat A.C., Osselton M.D., Widdop B. (2011). Clarke’s Analysis of Drugs and Poisons 4th ed., Pharmaceutical Press, London. Search in Google Scholar

3. Roche V.F., Zito S.W., Lemke L.T., Williams D.A. (eds) (2019). The Foye’s Principles of Medicinal Chemistry, 8th ed. Lippincott Williams & Wilkins, Philadelphia. Search in Google Scholar

4. Florence A.T., Attwood D. (2016) Physicochemical Principles of Pharmacy, 6th ed, Pharmaceutical Press, London. Search in Google Scholar

5. Jašović Gašić M, Vuković O, Pantović M, Cvetić T, Marić Bojović N: Antipsychotics – History of development and field of indication, new wine – old glasses. Psychiatria Danubina, 2012; 24 (Suppl. 3):342–344. Search in Google Scholar

6. Di L, Kerns EH: Profiling drug - like properties in discovery research. Curr. Opin. Chem. Biol. 2003; 7:402-408. Search in Google Scholar

7. Brunton L.L., Dandan R.H., Knollmann B.C. (2018). Goodman and Gilman’s: The Pharmacological Basis of Therapeutics, 13th ed. The McGraw-Hill Companies, Inc. China. Search in Google Scholar

8. Kerns E.H., Di L. (2008). Drug-like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization. Elsevier, USA. Search in Google Scholar

9. Hartmann T, Schmitt J: Lipophilicity – beyond octanol/ water: a short comparison of modern technologies. Drug Discov. Today Techn. 2004; 1(4):431-439. Search in Google Scholar

10. Remko M, Swart M, Bickelhaupt MF: Theoretical study of structure, pKa, lipophilicity, solubility, absorption and polar surface area of some centrally acting antihypertensives. Bioorg. Med. Chem. 2006; 14:1715-1728. Search in Google Scholar

11. Zhao YH, Le J, Abraham MH, Hersey A, Eddershaw PJ, Luscombe CN, Boutina D, Beck G, Sherbone B, Cooper I, Platts JA: Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure- activity relationship (QSAR) with the Abraham descriptors. J. Pharm. Sci. 2001; 90:749-784. Search in Google Scholar

12. Lipinski CA: Drug-like properties and the causes of poor solubility and poor permeability. J Pharmacol. Toxicol. Met. 2000; 44:235–249. Search in Google Scholar

13. Odović J, B Marković B, Injac R, Vladimirov S, Karljiković-Rajic K: Correlation between ultra-high performance liquid chromatography-tandem mass spectrometry and reversed-phase thin-layer chromatography hydrophobicity data for evaluation of angiotensin-converting enzyme inhibitors absorption. J. Chromatogr. A. 2012;1258: 94–100. Search in Google Scholar

14. Odovic J, Markovic B, Vladimirov S, Karljikovic-Rajic K: In Vitro modeling of angiotensin-converting enzyme inhibitor’s absorption with chromatographic retention data and selected molecular descriptors. J. Chromatogr. B. 2014;953: 102-107. Search in Google Scholar

15. Trbojević J, Odović J, Trbojević-Stanković J, Nešić D, Jelić R: The relationship between angiotensin II receptor antagonists’ bioavailability and molecular properties. Arch Biol Sci. 2016; 68(2): 273-8.10.2298/ABS150915015T Search in Google Scholar

16. Odovic J, Trbojevic-Stankovic J: Correlation between Angiotensin-converting enzyme inhibitors lipophilicity and protein binding data. Acta Medica Medianae. 2012; 51(4);13-18. Search in Google Scholar

17. Trbojević-Stanković J, Aleksić M, Odović J: Estimation of Angiotensin-Converting Enzyme Inhibitors Protein Binding Degree Using Chromatographic Hydrophobicity Data. Srp Arh Celok Lek 2015; 143(1-2): 50-55.10.2298/SARH1502050T25845252 Search in Google Scholar

18. Trbojević-Stanković J, Odović J, Jelić R, Nesić D, Stojimirović B: The influence of certain molecular descriptors on fecal elimination of angiotensin II receptor antagonists. Arch Biol Sci. 2015; 67(1):103-109.10.2298/ABS141104011T Search in Google Scholar

19. Trbojević-Stanković J, Odović J, Jelić R, Nesić D, Stojimirović B: The Effect of the Molecular Properties of Calcium Channel Blockers on Their Elimination Route. Arch Biol Sci. 2015; 67(3): 801-806.10.2298/ABS150127039T Search in Google Scholar

20. Trbojević J, Odović J, Trbojević-Stanković J, Stojimirović B, Jelić R. The evaluation of angiotensin converting enzyme Inhibitors in renal elimination with selected molecular descriptors. Serb J Exp Clin Res. 2017; 18(2): 119-123.10.1515/sjecr-2016-0100 Search in Google Scholar

21. Berić J, Jelić R, Nešić D, Trbojević-Stanković J, Odović J: Estimation of plasma protein binding of selected antipsychotics using computed molecular properties. Arch Biol Sci. 2017; 69(31): 463-468 Search in Google Scholar

22. Tetko IV. Virtual Computational Chemistry Laboratory. www.vcclab.org URL: http://www.vcclab.org/lab/alogps/ (date accessed 25.12.2019.) Search in Google Scholar

23. Molinspiration free Property Calculation Service from Bratislava University www.molinspiration.com URL: https://www.molinspiration.com/cgi-bin/propertie (date accessed 25.12.2019.) Search in Google Scholar

24. Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2017 www.drugbank.ca Available from URL: https://www.drugbank.ca/unearth/q?utf8=%E2%9C%93&searcher=drugs&query=antipsychotics (date accessed 25.12.2019.)10.1093/nar/gkx1037575333529126136 Search in Google Scholar

25. Zhao YH, Le J, Abraham MH, Hersey A, Eddershaw PJ, Luscombe CN, Boutina D, Beck G, Sherbone B, Cooper I, Platts JA: Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure- activity relationship (QSAR) with the Abraham descriptors. J. Pharm. Sci. 2001; 90:749-784. Search in Google Scholar

26. Zhao YH, Abraham MH, Le J, Hersey A, Luscombe CN, Beck G, Sherborne B, Cooper I: Rate-Limited Steps of Human Oral Absorption and QSAR Studies. Pharmac. Res. 2002;, 19:1446-1457. Search in Google Scholar

27. Mannhold R, Poda GI, Tetko I: Calculation of molecular lipophilicity: state-of-the-art and comparison of log P methods on more than 96,000 compounds. J.Pharm. Sci. 2009; 98: 861–893. Search in Google Scholar

28. Mandić Z. (ed) (2012). Physico-Chemical Methods in Drug Discovery and Development IAPC Publishing, Zagreb, Croatia.10.5599/obp.7.0 Search in Google Scholar

29. Asuero AG, Sayago A, Gonzalez AG: The correlation coefficient: An overview. Crit. Rev. Anal. Chem. 2006; 36:41-59. Search in Google Scholar

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