[
1. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med. 2003; 31: 1250-6.10.1097/01.CCM.0000050454.01978.3B
]Search in Google Scholar
[
2. Vincent, JL. The Clinical Challenge of Sepsis Identification and Monitoring, PLoS Med. 2016; 13(5): e1002022.10.1371/journal.pmed.1002022
]Search in Google Scholar
[
3. Vincent JL, Opal S, Marshall JC, Tracey KJ. Sepsis definitions: Time for change. Lancet. 2013; 381: 774-5.10.1016/S0140-6736(12)61815-7
]Search in Google Scholar
[
4. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). Jama. 2016; 315: 801-10.10.1001/jama.2016.0287
]Search in Google Scholar
[
5. Vincent JL, Mira JP, Antonelli M. Sepsis: older and newer concepts. Lancet Respir Med. 2016; 4(3): 237-40.10.1016/S2213-2600(15)00522-6
]Search in Google Scholar
[
6. Djordjevic D, Surbatovic M, Ugrinovic D, Radakovic S, Jevdjic J, Filipovic N, et al. New aspects of sepsis pathophysiology in critically ill. Vojnosanit Pregl. 2012; 69(1): 58-68.10.2298/VSP1201058D22397298
]Search in Google Scholar
[
7. Cho S, Choi J. Biomarkers of Sepsis. Infect Chemother. 2014; 46(1): 1-12.10.3947/ic.2014.46.1.1397031224693464
]Search in Google Scholar
[
8. Martin GS. Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes. Expert Rev Anti Infect Ther. 2012; 10(6): 701-6.10.1586/eri.12.50348842322734959
]Search in Google Scholar
[
9. Lagu T, Rothberg MB, Shieh MS, Pekow PS, Steingrub JS, Lindenauer PK. Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007. Crit Care Med. 2012; 40(3): 754-61.10.1097/CCM.0b013e318232db6521963582
]Search in Google Scholar
[
10. Balk RA. Severe sepsis and septic shock. Definitions, epidemiology, and clinical manifestations. Crit Care Clin. 2000; 16(2): 179-92.10.1016/S0749-0704(05)70106-8
]Search in Google Scholar
[
11. Vincent JL, Brealey D, Libert N, Abidi NE, O'Dwyer M, Zacharowski K, et al. Rapid Diagnosis of Infection in the Critically Ill, a Multicenter Study of Molecular Detection in Bloodstream Infections, Pneumonia, and Sterile Site Infections. Crit Care Med. 2015; 43(11): 2283-91.10.1097/CCM.0000000000001249460336426327198
]Search in Google Scholar
[
12. Oberhoffer M, Vogelsang H, Russwurm S Hariung T, Reinhart K. Outcome prediction by traditional a new markers of inflammation in patients with sepsis. Clin Chem Lab Med. 1999; 37: 363-8.10.1515/CCLM.1999.060
]Search in Google Scholar
[
13. Zohreh A, Elham P. Relationship between Age and Peripheral White Blood Cell Count in Patients with Sepsis. Int J Prev Med. 2011; 2(4): 238-42.
]Search in Google Scholar
[
14. Muller Kobold AC, Tulleken JE. Leukocyte activation in sepsis; correlations with disease state and mortality. Intensive Care Med. 2000; 26(7): 883-92.10.1007/s001340051277
]Search in Google Scholar
[
15. Joo K, Park W, Lim MJ, Kwon SR, Yoon J. Serum procalcitonin for differentiating bacterial infection from disease flares in patients with autoimmune diseases. J Korean Med Sci. 2011; 26(9): 1147-51.10.3346/jkms.2011.26.9.1147
]Search in Google Scholar
[
16. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013; 41(2): 580-637.10.1097/CCM.0b013e31827e83af
]Search in Google Scholar
[
17. Sallah JI, Japiassu AM, Soares M, Assis EF, Gomes RN, Bozza MT, et al. Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis. Crit Care. 2007; 11(2): R49.10.1186/cc5783
]Search in Google Scholar
[
18. Shabuj KH, Hossain J, Moni SC, Dey SK. C-reactive Protein (CRP) as a Single Biomarker for Diagnosis of Neonatal Sepsis: a Comprehensive Meta-analysis.Mymensingh Med J. 2017; 26(2): 364-71.
]Search in Google Scholar
[
19. Ticinesi A, Lauretani F, Nouvenne A, Porro E, Fanelli G, Maggio M, et al. C-reactive protein (CRP) measurement in geriatric patients hospitalized for acute infection. Eur J Intern Med. 2017; 37: 7-12.10.1016/j.ejim.2016.08.026
]Search in Google Scholar
[
20. Di Somma S, Magrini L, Travaglino F, Lalle I, Fiotti N, Cervellin G, et al. Opinion paper on innovative approach of biomarkers for infectious diseases and sepsis management in the emergency department. Clin Chem Lab Med. 2013; 51: 1167-75.10.1515/cclm-2012-0795
]Search in Google Scholar
[
21. Shiferaw B, Bekele E, Kumar K, Boutin A, Frieri M. The Role of Procalcitonin as a Biomarker in Sepsis. J Infect Dis Epidemiol. 2016; 2: 006.10.23937/2474-3658/1510006
]Search in Google Scholar
[
22. Russwin S, Wiederhold M, Oberhoffer M, Stonans I. Zipfel PF, Reinhart K. Molecular aspects and natural source of procalcitonin. Clin Chem Lab Med. 1999; 37(8): 789-97.10.1515/CCLM.1999.119
]Search in Google Scholar
[
23. Oberhoffer M, Stonans I, Russwurm S, Stonane E, Vogelsang H, Junker U, et al. Procalcitonin expression in human peripheral blood mononuclear cells and its modulation by lipopolysaccharides and sepsis-realted cytocines in vitro. J Lab Clin Med. 1999; 134(1): 49-55.10.1016/S0022-2143(99)90053-7
]Search in Google Scholar
[
24. Beqja-Lika A, Bulo-Kasneci A, Refatllari E, Heta-Alliu N, Rucaj-Barbullushi A, Mone I, et al. Serum procalcitonine levels as an early diagnostic indicator of sepsis. Mater Sociomed. 2013; 25(1): 23-5.10.5455/msm.2013.25.23-25
]Search in Google Scholar
[
25. Wacker C, Prkno A, Brunkhorst FM, Schlattmann P. Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis. Lancet Infect Dis. 2013; 13: 426-35.10.1016/S1473-3099(12)70323-7
]Search in Google Scholar
[
26. Afsar I, Sener AG. Is Procalcitonin a Diagnostic and/or Prognostic Marker in Sepsis? Infect Dis Clin Pract. 2015; 23: 3-6.10.1097/IPC.0000000000000187
]Search in Google Scholar