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Discriminability of the Beck Depression Inventory and its Abbreviations in an Adolescent Psychiatric Sample

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25. Apr. 2025

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FIGURE 1.

Flow diagram of participants based on the primary diagnostic categorization (MDD vs. no depression). Note: MDD vs. no depression diagnosis refers to the main comparison categorization used in the analysis. For more details, see Methods section: Research Diagnoses.
Flow diagram of participants based on the primary diagnostic categorization (MDD vs. no depression). Note: MDD vs. no depression diagnosis refers to the main comparison categorization used in the analysis. For more details, see Methods section: Research Diagnoses.

FIGURE 2a.

Sample-optimal cut-offs for the main diagnostic condition, MDD vs. no depression diagnosis, criterion Cohen's kappa, all participants together.
Sample-optimal cut-offs for the main diagnostic condition, MDD vs. no depression diagnosis, criterion Cohen's kappa, all participants together.

FIGURE 2b.

Sample-optimal cut-offs for the main diagnostic condition, MDD vs. no depression diagnosis, criterion Cohen's kappa, by gender.
Sample-optimal cut-offs for the main diagnostic condition, MDD vs. no depression diagnosis, criterion Cohen's kappa, by gender.

Figure 3.

BDI mean scores versus factor scores with fit lines. Note: The higher and lower horizontal cut-off lines correspond to BDI-IA sums 16 and 11, respectively, and the factor score cut-offs to the matched sensitivities.
BDI mean scores versus factor scores with fit lines. Note: The higher and lower horizontal cut-off lines correspond to BDI-IA sums 16 and 11, respectively, and the factor score cut-offs to the matched sensitivities.

BDI sum score distributions by version and diagnostic category_

Condition* Version Diagnosis + Diagnosis − Brunner–Munzel test Stochastic Superiority

n M SD n M SD Statistic p Estimate CI
MDD vs. no depr. BDI-1A 351 30.22 9.64 239 12.13 9.49 31.7 < 0.001 0.902 [0.88, 0.93]
MDD vs. no depr. BDI-SF 359 20.24 6.60 243 7.75 6.56 32.3 < 0.001 0.902 [0.88, 0.93]
MDD vs. no depr. BDI-PC 361 11.58 3.91 245 4.54 3.91 29.5 < 0.001 0.892 [0.87, 0.92]
MDD vs. no depr. BDI-6 368 10.02 3.04 246 4.00 3.29 32.7 < 0.001 0.899 [0.88, 0.92]
Depr. vs. none BDI-1A 389 29.13 10.04 239 12.13 9.49 28.3 < 0.001 0.884 [0.86, 0.91]
Depr. vs. none BDI-SF 397 19.53 6.87 243 7.75 6.56 28.7 < 0.001 0.885 [0.86, 0.91]
Depr. vs. none BDI-PC 399 11.20 4.03 245 4.54 3.91 26.8 < 0.001 0.876 [0.85, 0.90]
Depr. vs. none BDI-6 406 9.74 3.12 246 4.00 3.29 29.8 < 0.001 0.886 [0.86, 0.91]
MDD vs. no MDD BDI-1A 351 30.22 9.64 275 13.04 9.55 30.7 < 0.001 0.892 [0.87, 0.92]
MDD vs. no MDD BDI-SF 359 20.24 6.60 279 8.42 6.63 30.9 < 0.001 0.891 [0.87, 0.92]
MDD vs. no MDD BDI-PC 361 11.58 3.91 281 4.95 3.96 28.1 < 0.001 0.880 [0.85, 0.91]
MDD vs. no MDD BDI-6 368 10.02 3.04 282 4.40 3.35 30.2 < 0.001 0.883 [0.86, 0.91]

Diagnostic test results, MDD vs_ no depressive disorder, factor score cut-off equivalent to BDI-1A sum ≥ 16_

Version Items Factor score cut-off AP Confusion matrix Basic ratios κ Diagnostic odds ratio Number needed to diagnose Global test Individual test adjusted p-values


TP FP FN TN Sens. Spec. PPV NPV DOR 95% Cl NND 95% Cl Stat. Adj. p Sens. Spec.
BDI-1A 21 −0.35 70% 350 85 23 164 0.938 0.659 0.805 0.877 0.623 29.36 [17.87, 48.24] 1.68 [1.48, 1.98] 2.70 0.250
BDI-SF 13 −0.33 70% 350 85 23 164 0.938 0.659 0.805 0.877 0.623 29.36 [17.87, 48.24] 1.68 [1.48, 1.98] 1.34 0.512
BDI-PC 7 −0.32 71% 350 90 23 159 0.938 0.639 0.795 0.874 0.604 26.88 [16.39, 44.09] 1.73 [1.52, 2.06] 0.04 0.980
BDI-6 6 −0.35 70% 350 86 23 163 0.938 0.655 0.803 0.876 0.619 28.84 [17.56, 47.37] 1.69 [1.48, 2.00] 0.36 0.835

Version membership and standardized one-factor model parameters of BDI-IA items

Item Content Item included in version Factor loading Item thresholds


BDI-SF BDI-PC BDI-6 1 2 3
1 Mood 0.80 −0.51 0.64 1.52
2 Pessimism 0.75 −0.83 0.25 1.12
3 Sense of failure 0.84 −0.74 0.45 1.11
4 Lack of satisfaction 0.83 −0.55 0.44 1.46
5 Guilty feeling 0.88 −0.46 0.28 1.00
6 Sense of punishment 0.65 0.07 0.74 1.27
7 Negative self-view 0.84 −0.69 0.32 0.96
8 Self-accusations 0.81 −0.90 −0.21 0.31
9 Self-destructiveness 0.70 −0.68 1.12 2.11
10 Crying 0.71 −0.48 0.26 0.69
11 Irritability 0.66 −0.92 0.32 1.31
12 Social withdrawal 0.74 −0.36 0.64 1.82
13 Indecisiveness 0.75 −0.68 0.05 1.60
14 Negative body image 0.73 −0.13 0.36 0.63
15 Work inhibition 0.71 −0.91 −0.03 1.49
16 Sleep disturbance 0.56 −0.67 0.81 1.34
17 Fatigability 0.78 −0.78 0.08 1.26
18 Loss of appetite 0.58 −0.05 0.73 1.54
19 Weight loss 0.24 0.68 1.19 1.73
20 Somatic preoccupation 0.42 0.25 1.48 1.93
21 Loss of libido 0.58 0.20 0.93 1.62

Characteristics and presence of SCID-based diagnoses by gender_

Variable Males Females Total
Participants 202 550 752
Age, mean 16.74 16.47 16.55
Age, SD 1.67 1.62 1.64
Major depressive disorder 84 (42%) 294 (53%) 378 (50%)
Dysthymia 24 (12%) 87 (16%) 111(15%)
Other depressive disorder 7 (3.5%) 29 (5%) 36 (5%)
Exclusion diagnosis 6 (3%) 61 (11%) 67 (9%)

Diagnostic test results, MDD vs_ no depressive disorder, mean score cut-off equivalent to BDI-1A sum ≥ 16_

Version Items Mean cut-off AP Confusion matrix Basic ratios κ Diagnostic odds ratio Number needed to diagnose Global test Individual test adjusted p-values


TP FP FN TN Sens. Spec. PPV NPV DOR 95% Cl NND 95% Cl Stat. Adj. p Sens. Spec.
BDI-1A 21 0.76 71% 350 89 23 160 0.938 0.643 0.797 0.874 0.608 27.36 [16.67, 44.89] 1.72 [1.51, 2.05]
BDI-SF 13 0.82 69% 348 84 25 165 0.933 0.663 0.806 0.868 0.620 27.34 [16.86, 44.34] 1.68 [1.48, 1.99] 2.22 0.329
BDI-PC 7 0.86 72% 354 95 19 154 0.949 0.618 0.788 0.890 0.598 30.20 [17.82, 51.19] 1.76 [1.54, 2.10] 3.12 0.211
BDI-6 6 1.00 69% 349 81 24 168 0.936 0.675 0.812 0.875 0.634 30.16 [18.45, 49.29] 1.64 [1.45, 1.93] 2.36 0.307

Optimal cut-off results_

BDI version Optimization criterion Subgroup Optimal cut-off κ Sensitivity Specificity AUC DOR NND
BDI-1A Cohen's kappa - 0.89 0.638 0.895 0.731 0.902 1.60
BDI-SF Cohen's kappa - 1.01 0.619 0.845 0.775 0.903 1.61
BDI-PC Cohen's kappa - 1.10 0.634 0.861 0.771 0.893 1.58
BDI-6 Cohen's kappa - 1.04 0.615 0.866 0.743 0.900 1.64
BDI-1A Cohen's kappa Male 0.86 0.682 0.821 0.860 0.910 1.47
BDI-1A Cohen's kappa Female 0.90 0.611 0.927 0.654 0.896 1.72
BDI-SF Cohen's kappa Male 0.79 0.629 0.869 0.763 0.912 1.58
BDI-SF Cohen's kappa Female 1.07 0.597 0.886 0.699 0.896 1.71
BDI-PC Cohen's kappa Male 1.01 0.646 0.738 0.903 0.893 1.56
BDI-PC Cohen's kappa Female 1.12 0.605 0.896 0.692 0.890 1.70
BDI-6 Cohen's kappa Male 0.95 0.650 0.857 0.796 0.895 1.53
BDI-6 Cohen's kappa Female 1.14 0.623 0.910 0.692 0.899 1.66
BDI-1A Misclassification cost 1:1 - 0.86 0.638 0.895 0.731 0.902 1.60
BDI-SF Misclassification cost 1:1 - 0.89 0.606 0.893 0.699 0.903 1.69
BDI-PC Misclassification cost 1:1 - 1.05 0.634 0.861 0.771 0.893 1.58
BDI-6 Misclassification cost 1:1 - 1.02 0.615 0.866 0.743 0.900 1.64
BDI-1A Misclassification cost 1:3 - 0.62 0.599 0.962 0.602 0.902 1.77
BDI-SF Misclassification cost 1:3 - 0.68 0.611 0.979 0.594 0.903 1.75
BDI-PC Misclassification cost 1:3 - 0.72 0.594 0.949 0.614 0.893 1.77
BDI-6 Misclassification cost 1:3 - 0.74 0.565 0.957 0.574 0.900 1.88
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