<abstract xmlns="http://www.w3.org/1999/xhtml">

<bold>Introduction</bold>: NAFLD is strongly associated with metabolic syndrome, and for many years, fatty liver was an exclusive feature of obese patients. The study tries to assess whether the body mass index (BMI) and body circumference is correlated to steatosis, fibrosis, or inflammatory activity of the liver.
<bold>Methods</bold>: 81 patients with recent hepatic biopsy were included in the study and were weighed and measured. The biopsy results were compared to the measurements.
<bold>Results</bold>: The average BMI overall for the whole lot was 30.16. There was a significant difference in BMI across the inflammatory activity categories (p = 0.009): groups with higher necro inflammatory activity tended to have higher BMI values (average values per grade: 0–28, 1–29, 2–33, 3–32, 4–29). There was no significant difference for grades of steatosis (p = 0.871). With regards to waist circumference, the overall average was 90.70cm/35.70in. There was a significant difference across the steatosis categories (p &lt; 0.001): groups with higher steatosis scores had higher waist circumferences (average values per grade: 1–77cm / 30 in, 2–95 cm / 37 in, 3–94 cm / 37 in). There was no significant difference for grades of activity (p = 0.058).
<bold>Conclusion</bold>: BMI and waist circumference are easy to measure, non-invasive parameters, which could be useful in screening patients at higher risk for necro inflammatory activity or severe steatosis.
</abstract>

Introduction: NAFLD is strongly associated with metabolic syndrome, and for many years, fatty liver was an exclusive feature of obese patients. The study tries to assess whether the body mass index (BMI) and body circumference is correlated to steatosis, fibrosis, or inflammatory activity of the liver.
Methods: 81 patients with recent hepatic biopsy were included in the study and were weighed and measured. The biopsy results were compared to the measurements.
Results: The average BMI overall for the whole lot was 30.16. There was a significant difference in BMI across the inflammatory activity categories (p = 0.009): groups with higher necro inflammatory activity tended to have higher BMI values (average values per grade: 0–28, 1–29, 2–33, 3–32, 4–29). There was no significant difference for grades of steatosis (p = 0.871). With regards to waist circumference, the overall average was 90.70cm/35.70in. There was a significant difference across the steatosis categories (p < 0.001): groups with higher steatosis scores had higher waist circumferences (average values per grade: 1–77cm / 30 in, 2–95 cm / 37 in, 3–94 cm / 37 in). There was no significant difference for grades of activity (p = 0.058).
Conclusion: BMI and waist circumference are easy to measure, non-invasive parameters, which could be useful in screening patients at higher risk for necro inflammatory activity or severe steatosis.

The correlation between Body Mass Index and histological features of Nonalcoholic Fatty Liver Disease

Internal Medicine II and Gastroenterology Department

“Carol Davila” University of Medicine and Pharmacy Bucharest

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Introduction: NAFLD is strongly associated with metabolic syndrome, and for many years, fatty liver was an exclusive feature of obese patients. The study tries...

The correlation between Body Mass Index and histological features of Nonalcoholic Fatty Liver Disease

Online veröffentlicht: 06. Mai 2023

Seitenbereich: 147 - 153

Eingereicht: 23. Apr. 2023

DOI: https://doi.org/10.2478/rjim-2023-0011

Schlüsselwörter
Non-alcoholic Fatty Liver Disease, Body Mass Index, Weist circumference, Liver biopsy, Inflammatory activity, Steatosis, Fibrosis

© 2023 Ana Calin-Necula et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The correlation between Body Mass Index and histological features of Nonalcoholic Fatty Liver Disease

Online veröffentlicht: 06. Mai 2023

Seitenbereich: 147 - 153

Eingereicht: 23. Apr. 2023

DOI: https://doi.org/10.2478/rjim-2023-0011

SchlüsselwörterNon-alcoholic Fatty Liver Disease, Body Mass Index, Weist circumference, Liver biopsy, Inflammatory activity, Steatosis, Fibrosis

© 2023 Ana Calin-Necula et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
Non-alcoholic Fatty Liver Disease, Body Mass Index, Weist circumference, Liver biopsy, Inflammatory activity, Steatosis, Fibrosis