<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Background</h3>
<p>Computer-aided diagnosis (<italic>i.e.</italic>, texture analyses) tools are becoming increasingly beneficial methods to monitor subtle tissue changes. The aim of this pilot study was to investigate short-term effect of platelet rich plasma (PRP) treatment in supraspinatus and common extensor of the forearm tendinosis by using texture analysis of ultrasound (US) images as well as by clinical questionnaires.</p>
</sec>
<sec><h3>Patients and methods</h3>
<p>Thirteen patients (7 male and 6 female, age 36–60 years, mean age 51.2 ± 5.2) were followed after US guided PRP treatment for tendinosis of two tendons (9 patients with lateral epicondylitis and 4 with supraspinatus tendinosis). Clinical and US assessment was performed prior to as well as 3 months after PRP treatment with validated clinical questionnaires. Tissue response in tendons was assessed by using gray level run length matrix method (GLRLM) of US images.</p>
</sec>
<sec><h3>Results</h3>
<p>All patients improved of tendinosis symptoms after PRP treatment according to clinical questionnaires. Almost all GLRLM features were statistically improved 3 months after PRP treatment. GLRLM-long run high gray level emphasis (LRLGLE) revealed the best moderate positive and statistically significant correlation after PRP (<italic>r</italic> = 0.4373, <italic>p</italic> = 0.0255), followed by GLRLM-low gray level run emphasis (LGLRE) (<italic>r</italic> = 0.3877, <italic>p</italic> = 0.05).</p>
</sec>
<sec><h3>Conclusions</h3>
<p>Texture analysis of tendinosis US images was a useful quantitative method for the assessment of tendon remodeling after minimally invasive PRP treatment. GLRLM features have the potential to become useful imaging biomarkers to monitor spatial and time limited tissue response after PRP, however larger studies with similar protocols are needed.</p>
</sec>
</abstract>

Background
Computer-aided diagnosis (i.e., texture analyses) tools are becoming increasingly beneficial methods to monitor subtle tissue changes. The aim of this pilot study was to investigate short-term effect of platelet rich plasma (PRP) treatment in supraspinatus and common extensor of the forearm tendinosis by using texture analysis of ultrasound (US) images as well as by clinical questionnaires.

Patients and methods
Thirteen patients (7 male and 6 female, age 36–60 years, mean age 51.2 ± 5.2) were followed after US guided PRP treatment for tendinosis of two tendons (9 patients with lateral epicondylitis and 4 with supraspinatus tendinosis). Clinical and US assessment was performed prior to as well as 3 months after PRP treatment with validated clinical questionnaires. Tissue response in tendons was assessed by using gray level run length matrix method (GLRLM) of US images.

Results
All patients improved of tendinosis symptoms after PRP treatment according to clinical questionnaires. Almost all GLRLM features were statistically improved 3 months after PRP treatment. GLRLM-long run high gray level emphasis (LRLGLE) revealed the best moderate positive and statistically significant correlation after PRP (r = 0.4373, p = 0.0255), followed by GLRLM-low gray level run emphasis (LGLRE) (r = 0.3877, p = 0.05).

Conclusions
Texture analysis of tendinosis US images was a useful quantitative method for the assessment of tendon remodeling after minimally invasive PRP treatment. GLRLM features have the potential to become useful imaging biomarkers to monitor spatial and time limited tissue response after PRP, however larger studies with similar protocols are needed.

Assessment of short-term effect of platelet-rich plasma treatment of tendinosis using texture analysis of ultrasound images

Department of Radiology, Faculty of Medicine

Center of Clinical Physiology, Medical Faculty

Laboratory for Haemostasis and Atherothrombosis

Institute of Physiology, Faculty of Medicine

Radiology and Oncology

This work is licensed under the Creative Commons Attribution 4.0 International License.

Background
Computer-aided diagnosis (i.e., texture analyses) tools are becoming increasingly beneficial methods to monitor subtle tissue changes. The aim of...

Assessment of short-term effect of platelet-rich plasma treatment of tendinosis using texture analysis of ultrasound images

Article Category: Research Article

Online veröffentlicht: 30. Nov. 2023

Seitenbereich: 465 - 472

Eingereicht: 14. Juni 2023

Akzeptiert: 06. Aug. 2023

DOI: https://doi.org/10.2478/raon-2023-0054

Schlüsselwörter
texture analysis, tendinosis, platelet-rich plasma, ultrasonography

© 2023 Karlo Pintaric et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

FIGURE 1.

FIGURE 2.

FIGURE 3.

Assessment of short-term effect of platelet-rich plasma treatment of tendinosis using texture analysis of ultrasound images

Article Category: Research Article

Online veröffentlicht: 30. Nov. 2023

Seitenbereich: 465 - 472

Eingereicht: 14. Juni 2023

Akzeptiert: 06. Aug. 2023

DOI: https://doi.org/10.2478/raon-2023-0054

Schlüsselwörtertexture analysis, tendinosis, platelet-rich plasma, ultrasonography

© 2023 Karlo Pintaric et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

FIGURE 1.

FIGURE 2.

FIGURE 3.

Schlüsselwörter
texture analysis, tendinosis, platelet-rich plasma, ultrasonography