<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_raon-2021-0009_s_010_w2aab3b7c51b1b6b1aab1c16b1Aa"><h3>Background</h3><p>Endometrial cancer (EC) represents a high health burden in Slovenia and worldwide. The incidence is increasing due to lifestyle and behavioural risk factors such as obesity, smoking, oestrogen exposure and aging of the population. In many cases, endometrial cancer is diagnosed at an early stage due to obvious signs and symptoms. The standard treatment is surgery with or without adjuvant therapy, depending on the stage of the disease and the risk of recurrence. However, treatment modalities have changed in the last decades, considerably in the extent of lymphadenectomy.</p></sec><sec id="j_raon-2021-0009_s_011_w2aab3b7c51b1b6b1aab1c16b2Aa"><h3>Conclusions</h3><p>The gold standard of treatment for is surgery, which may be the only treatment modality in the early stages of low-grade tumours. In recent years, a minimally invasive approach with sentinel node biopsy (SNB) has been proposed. A conservative approach with hormonal treatment is used if fertility preservation is desired. If EC is in advance stage, high-risk histology, or high grade, radiotherapy, chemotherapy, or a combination of both is recommended.</p></sec></abstract>

BackgroundEndometrial cancer (EC) represents a high health burden in Slovenia and worldwide. The incidence is increasing due to lifestyle and behavioural risk factors such as obesity, smoking, oestrogen exposure and aging of the population. In many cases, endometrial cancer is diagnosed at an early stage due to obvious signs and symptoms. The standard treatment is surgery with or without adjuvant therapy, depending on the stage of the disease and the risk of recurrence. However, treatment modalities have changed in the last decades, considerably in the extent of lymphadenectomy.ConclusionsThe gold standard of treatment for is surgery, which may be the only treatment modality in the early stages of low-grade tumours. In recent years, a minimally invasive approach with sentinel node biopsy (SNB) has been proposed. A conservative approach with hormonal treatment is used if fertility preservation is desired. If EC is in advance stage, high-risk histology, or high grade, radiotherapy, chemotherapy, or a combination of both is recommended.

Surgical treatment and fertility perservation in endometrial cancer

Radiology and Oncology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Surgical treatment and fertility perservation in endometrial cancer"}

BackgroundEndometrial cancer (EC) represents a high health burden in Slovenia and worldwide. The incidence is increasing due to lifestyle and behavioural risk...

Surgical treatment and fertility perservation in endometrial cancer

Article Category: Review

Online veröffentlicht: 11. Feb. 2021

Seitenbereich: 144 - 149

Eingereicht: 24. Nov. 2020

Akzeptiert: 18. Jan. 2021

DOI: https://doi.org/10.2478/raon-2021-0009

© 2021 Nina Kovacevic, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.