Three-dimensional MRI evaluation of the effect of bladder volume on prostate translocation and distortion
Article Category: Research Article
Online veröffentlicht: 14. Jan. 2020
Seitenbereich: 48 - 56
Eingereicht: 08. Nov. 2019
Akzeptiert: 19. Dez. 2019
DOI: https://doi.org/10.2478/raon-2020-0001
© 2020 Ziga Snoj, Andrew B. Gill, Leonardo Rundo, Nikita Sushentsev, Tristan Barrett, published by Sciendo
This work is licensed under the Creative Commons Attribution 3.0 Public License.
Background
The accuracy of any radiation therapy delivery is limited by target organ translocation and distortion. Bladder filling is one of the recognised factors affecting prostate translocation and distortion. The purpose of our study was to evaluate the effect of bladder volume on prostate translocation and distortion by using detailed three-dimensional prostate delineation on MRI.
Patients and methods
Fifteen healthy male volunteers were recruited in this prospective, institutional review board-approved study. Each volunteer underwent 4 different drinking preparations prior to imaging, with MR images acquired pre- and post-void. MR images were co-registered by using bony landmarks and three-dimensional contouring was performed in order to assess the degree of prostate translocation and distortion. According to changes in bladder or rectum distention, subdivisions were made into bladder and rectal groups. Studies with concomitant change in both bladder and rectal volume were excluded.
Results
Forty studies were included in the bladder volume study group and 8 in the rectal volume study group. The differences in rectal volumes yielded higher levels of translocation (
Conclusions
Bladder volume has a minimal effect on prostate translocation and effect on prostate distortion is negligible. Prostate translocation may be minimalised if there is < 2-fold increase in the bladder volume.