<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Study of the influence of vibration oscillations of different frequency, amplitude and vibration acceleration on the structural and functional state and mechanisms of muscle tissue remodelling. An experimental study was conducted on sexually mature male rats. The rats of the four experimental groups were subjected to vertical vibration oscillations of 15, 25, 50 and 75 Hz, respectively. It has been established that pathological changes in muscle tissue in the form of different variants of damage and remodelling tend to increase, which correlates with the frequency of vibration, amplitude and vibration acceleration level, as in the 2nd group, where the maximum permissible vibration levels did not exceed the established allowable norms, and in other groups of animals, where the permissible levels of total vibration were exceeded. By increasing vibration acceleration for more than 1.25 m/s2 (0.13 g, frequency more than 25 Hz and amplitude of 2 mm), severe damages are observed in the form of alterative changes of muscle fibres with the disappearance of transverse strain, homogenization of sarcoplasm, fragmentation with dissociation fibres on separate beams, partial and subtotal myocytolysis, and necrosis of separate fibres. Inflammation is rapidly increasing with the increase in the frequency of vibration and the level of vibration acceleration for more than 5.0 m/s2 (0.51 g).</p></abstract>

Study of the influence of vibration oscillations of different frequency, amplitude and vibration acceleration on the structural and functional state and mechanisms of muscle tissue remodelling. An experimental study was conducted on sexually mature male rats. The rats of the four experimental groups were subjected to vertical vibration oscillations of 15, 25, 50 and 75 Hz, respectively. It has been established that pathological changes in muscle tissue in the form of different variants of damage and remodelling tend to increase, which correlates with the frequency of vibration, amplitude and vibration acceleration level, as in the 2nd group, where the maximum permissible vibration levels did not exceed the established allowable norms, and in other groups of animals, where the permissible levels of total vibration were exceeded. By increasing vibration acceleration for more than 1.25 m/s2 (0.13 g, frequency more than 25 Hz and amplitude of 2 mm), severe damages are observed in the form of alterative changes of muscle fibres with the disappearance of transverse strain, homogenization of sarcoplasm, fragmentation with dissociation fibres on separate beams, partial and subtotal myocytolysis, and necrosis of separate fibres. Inflammation is rapidly increasing with the increase in the frequency of vibration and the level of vibration acceleration for more than 5.0 m/s2 (0.51 g).

The Peculiarities of Remodelling Muscle Tissue of Rats Under the Vibration Influence

Danylo Halytsky Lviv National Medical University

Department of Toxicological and Analytical Chemistry

Department of Pathological Anatomy and Forensic Medicine

PRILOZI

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Study of the influence of vibration oscillations of different frequency, amplitude and vibration acceleration on the structural and functional state and...

The Peculiarities of Remodelling Muscle Tissue of Rats Under the Vibration Influence

Online veröffentlicht: 31. Mai 2019

Seitenbereich: 59 - 65

DOI: https://doi.org/10.2478/prilozi-2019-0004

Schlüsselwörter
muscle tissue, remodelling, whole body vibrationx

© 2019 Nazar M. Kostyshyn et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

The Peculiarities of Remodelling Muscle Tissue of Rats Under the Vibration Influence

Online veröffentlicht: 31. Mai 2019

Seitenbereich: 59 - 65

DOI: https://doi.org/10.2478/prilozi-2019-0004

Schlüsselwörtermuscle tissue, remodelling, whole body vibrationx

© 2019 Nazar M. Kostyshyn et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Schlüsselwörter
muscle tissue, remodelling, whole body vibrationx