Isolation of citronellal and geraniol from citronella (Cymbopogon winterianus) oil by vacuum fractional distillation: Effect of operating conditions on the separation

1 Sharmeen, J.B., Mahomoodally, F.M. Zengin, G. & Maggi, F. 2021. Essential Oils as Natural Sources of Fragrance Compounds for Cosmetics and Cosmeceuticals. Molecules, 26, 3, 666. DOI: 10.3390/molecules26030666. Search in Google Scholar

2 “Essential Oils Market Outlook Report 2026 – Growth Statistics,” Global Market Insight Inc2019. Search in Google Scholar

3 Sell, C.S. 2006. The Chemistry of Fragrances: From Perfumer to Consumer, RSC Publishing, USA. Search in Google Scholar

4 Chen, W. & Viljoen, A.M. 2010. Geraniol – A review of a commercially important fragrance material. South Afr. J. Botany, 76(4), 643–651. DOI: 10.1016/j.sajb.2010.05.008. Search in Google Scholar

5 Lenardao, E., Giancarlo, V., Botteselle, Francisco de Azambuja, Gelson Perin, & Raquel G. Jacob, 2007. Citronellal as Key Compound in Organic Synthesis. Tetrahedron, 63, 6671–6712. DOI: 10.1016/j.tet.2007.03.159. Search in Google Scholar

6 Sell, C.S. 2003. A Fragrant Introduction to Terpenoid Chemistry, Royal Society of Chemistry, London. Search in Google Scholar

7 Wany, A., Jha, S., Nigam, V.K. & Pandey, D.M. 2013. Chemical analysis and therapeutic uses of citronella oil from Cymbopogon winterianus: A short review. Internat. J. Adv. Res., 1, 504–521. Search in Google Scholar

8 Standardization IOf Standards, 2016. ISO 3846:2016: Essential oil of citronella, Java type, USA. Search in Google Scholar

9 Manurung, R., Melinda, R., Abduh, M.Y. Widiana, A., Sugoro, I. & Suheryadi, D. 2015. Potential Use of Lemongrass (Cymbopogon winterianus) Residue as Dairy Cow Feed. Pakistan J. Nutrition, 14, 919–923. DOI: 10.3923/pjn.2015.919.923. Search in Google Scholar

10 Statistics of main exports and imports (2005), General Department of Vietnam Customs. Access on: August 20, 2021. [Online]. Available: https://www.customs.gov.vn/home.aspx?language=en-US. Search in Google Scholar

11 Bimantio, M., & Wardoyo, A. 2020. Sensitivity and Feasibility Analysis of Citronella Oil Business. SOCA: J. Sosial, Ekonomi Pertanian, 14, 313–324. DOI: 10.24843/SOCA.2020. v14.i02.p11. Search in Google Scholar

12 Guenther, E. 2014. The Essential Oils: History - Origin in Plants – Production – Analysis (The Essential Oils, vol. 1), Read Books Limited, USA. Search in Google Scholar

13 Zhang Keqin, He Chunmao, Chen Zuhong, Deng Qian, Wu Mingfeng, and Li Huajie, “Standardized recombinant tea tree oil and preparing method thereof,” China Patent CN101829074A, 2010. Search in Google Scholar

14 Martinez, J.L. 2007. Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds, CRC Press, New York. Search in Google Scholar

15 Reverchon, E., Porta, G.D. & Senatore, F. 1995. Super-critical CO₂ Extraction and Fractionation of Lavender Essential Oil and Waxes. J. Agric. Food Chem., 43(6), 1654–1658. DOI: 10.1021/jf00054a045. Search in Google Scholar

16 Porta, G.D., Porcedda, S., Marongiu, B. & Reverchon, E. 1999. Isolation of eucalyptus oil by supercritical fluid extraction. Flavour and Fragrance J., 14(4), 214–218. DOI: 10.1002/(SICI)1099-1026(199907/08)14:4<214::AID-FFJ814>3.0.CO;2-H. Search in Google Scholar

17 Budich, M.S., Heilig, T., Wesse, V., Leibküchler, ???& Brunner, G. 1999. Countercurrent deterpenation of citrus oils with supercritical CO₂. J. Supercritical Fluids, 14(2), 105–114. DOI: 10.1016/S0896-8446(98)00112-0. Search in Google Scholar

18 Reverchon, E., Marciano, A. & Poletto, M. 1997. Fractionation of a Peel Oil Key Mixture by Supercritical CO₂ in a Continuous Tower. Ind. & Engin. Chem. Res., 36, 11, 4940–4948. DOI: 10.1021/ie970199x. Search in Google Scholar

19 Mujtaba, I.M. 2004. Batch Distillation: Design and Operation (Series On Chem. Engin., vol. 3), Imperial College Press, London. Search in Google Scholar

20 Beneti, S.C., Rosset, E., Corazza, M.L., Frizzo, C.D., Luccio, M.D., Oliveira, J.V. 2011. Fractionation of citronella (Cymbopogon winterianus) essential oil and concentrated orange oil phase by batch vacuum distillation. J. Food Engin., 102(4), 348–354. DOI: 10.1016/j.jfoodeng.2010.09.011. Search in Google Scholar

21 Anwar, Y. & Siringoringo, V. 2020. Fractionation of Citronella Oil and Identification of Compounds by Gas Chromatography-Mass Spectrometry. Pharmac. Sci. Res., 7, 138–144. DOI: 10.7454/psr.v7i3.1101. Search in Google Scholar

22 Egi, A., Sulaswatty, A.,Tasrif, J.A.L. & Adilina, I.B. 2007. Pemisahan sitronelal dari minyak sereh wangi menggunakan unit fraksionasi skala bench (in ind). J. Agroind. Technol., 17(2), 49–53. Search in Google Scholar

23 Warsito, W., Chandrawati Cahyani, Sukardi, and Mafud Cahayo, 2019. Effect of Column Length in Batch Vacuum Fractionation on The Distribution of Major Components of Citronella Oil (Cymbopogon winterianus). IOP Conference Series: Mat. Sci. Engin., 546, 22–33. DOI: 10.1088/1757-899X/546/2/022033. Search in Google Scholar

24 Do DN, DP Nguyen, VD Phung, XT Le, TM Le, VM Do, BQ Minh, and XC Luu, 2021. Fractionating of Lemongrass (Cymbopogon citratus) Essential Oil by Vacuum Fractional Distillation. Processes, 9, 593–604. DOI: 10.3390/pr9040593. Search in Google Scholar

25 Eden, W., Alighiri, D., Cahyono, E., Supardi, K.I. & Wijayati, N. 2018. Fractionation of Java Citronella Oil and Citronellal Purification by Batch Vacuum Fractional Distillation. IOP Conference Series: Mat. Sci. Engin., 349. DOI: 10.1088/1757-899X/349/1/012067. Search in Google Scholar

26 Coker A.K. 2010. Distillation, packed towers, petroleum fractionation, gas processing and dehydration 4th ed. (Ludwig’s Applied Process Design for Chemical and Petrochemical Plants, vol. 2), Elsevier Science. Search in Google Scholar

27 Haynes, W.M. 2017. CRC Handbook of Chemistry and Physics 97 ed., CRC Press LLC, Boca Raton. Search in Google Scholar

28 Distributed Structure – Searchable Toxicity Database, United States Environmental Protection Agency. Access on: May 31, 2021. [Online]. Available: https://comptox.epa.gov/dashboard/. Search in Google Scholar

29 Barber, L.A. & Hall, M.D. 1950. Citronella Oil. Economic Botany, 4(4), 322–336. DOI: 10.1007/BF02985090. Search in Google Scholar

30 Songkro, S., Hayook, N., Jaisawang, J. Maneenuan, D., Chuchome, T. & Kaewnopparat, N. 2012. Investigation of inclusion complexes of citronella oil, citronellal and citronellol with β-cyclodextrin for mosquito repellent. J. Inclus. Phenomena Macroc. Chem., 72, 339–355. DOI: 10.1007/s10847-011-9985-7. Search in Google Scholar

31 Kakaraparthi, P.S., Srinivas, K.V.N.S., Kumar, J.K., Kumar, A.N., Rajput, D.K. & Sarma, V.U.M. 2014. Variation in the essential oil content and composition of Citronella (Cymbopogon winterianus Jowitt.) in relation to time of harvest and weather conditions. Industrial Crops and Products, 61, 240–248. DOI: 10.1016/j.indcrop.2014.06.044. Search in Google Scholar

32 Lorenzo, D., Dellacassa, E., Atti-Serafini, L., Santos, A.C., Frizzo, C., Paroul, N., Moyna, P., Mondello, L. & Dugo, G. 2000. Composition and stereoanalysis of Cymbopogon winterianus Jowitt oil from Southern Brazil. Flavour Fragr. J., 15, 177–181. DOI: 10.1002/1099-1026(200005/06)15:33.0.CO;2-M. Search in Google Scholar

33 Herath, H.M.W. Iruthayathas, E.E. & Ormrod, D.P. 1979. Temperature effects on essential oil composition of citronella selections. Economic Botany, 33(4), 425–430. DOI: 10.1007/BF02858338. Search in Google Scholar

34 Mortimer, R.G. 2008. Physical Chemistry 3rd ed., Academic Press, USA. Search in Google Scholar

35 Achmad, M., 1990. The Isolation of Citronella Oil Components by Fractional Distillation on Kilo Scale (in Ind). J. Agro-based Ind., 7(1), 33–36. DOI: 10.32765/warta%20ihp. v7i01.2318. Search in Google Scholar

36 Green, D.W. and Perry, R.H. 2007. Perry’s Chemical Engineers’ Handbook, McGraw-Hill Education, USA. Search in Google Scholar

37 Carney, T.P. 1949. Laboratory Fractional Distillation, Macmillan, New York. Search in Google Scholar

38 Clark, S.R. 2008. Elements of Fractional Distillation 4th ed., McGraw-Hill Book Company, Inc, New York. Search in Google Scholar

39 Rihayat, T., Suryani, U., Hasanah, Nurhanifa, JP Siregar, J Jaafar, T Cionita, and Fitria, 2020. Geraniol quality improvement on citronella oil as raw material for making anti-bacterial perfumes. IOP Conference Series: Mat., Sci. & Engin., 788, 12–28. DOI: 10.1088/1757-899X/788/1/012028. Search in Google Scholar

40 McCabe W et al., 2005. Unit Operations of Chemical Engineering 7th ed., McGraw-Hill Education, USA. Search in Google Scholar