The epidemic is affecting the global economy, plunging many industries. The global scale of the epidemic and government controls, restrictions and constraints have led to imbalances in world trade and have put many companies under pressure. The epidemic is a test of individual companies’ ability to operate effectively under new conditions, including occupational risk management. The research was conducted using a questionnaire method, the study was attended by 199 respondents. The research is burdened with an error in the selection of statistical sample units, which resulted from the respondents’ involvement and their truthfulness. The research was burdened with an estimation error of 0.07. The research was divided into two parts related to freezing the economy and social life and their defrosting. The aim of the article is to assess the occupational risk management activities that determine the prevention of OSH in an extreme situation, which was the immediate freezing of the economy and social activity in connection with the epidemic and then their gradual unfreezing. The conducted research allowed confirming the accepted hypothesis that the effectiveness of actions protecting the health of employees, and thus the production capacity of enterprises in a crisis situation, is related to the size of the plant, and this may be indirectly related to the system of organization of occupational health and safety services in the country.