<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_jvetres-2020-0072_s_005_w2aab3b7c67b1b6b1aab1c14b1Aa"><h3>Introduction</h3><p>Candida species are a natural component of the intestinal tract microflora, but in favourable conditions they can cause superficial, mucosal, or even systemic candidiasis. Poultry production might be a source of human drug-resistant yeast infections, including <italic>Candida</italic> spp. The limited data concerning the antifungal susceptibility of poultry <italic>Candida</italic> isolates prompted us to carry out research to determine the susceptibility of isolates from turkey intestinal tracts.</p></sec><sec id="j_jvetres-2020-0072_s_006_w2aab3b7c67b1b6b1aab1c14b2Aa"><h3>Method and Materials</h3><p>The beak cavity, crop and cloaca were swabbed of 580 turkeys from 58 flocks in western Poland. The susceptibility tests were conducted using the E-test method with amphotericin B, fluconazole, itraconazole, and voriconazole on 52 isolates of <italic>C. albicans</italic>, <italic>C. catenulata</italic>, <italic>C. glabrata</italic>, <italic>C. palmioleophila</italic>, <italic>C. rugosa</italic>, <italic>C. krusei</italic> and <italic>C. lusitaniae</italic>.</p></sec><sec id="j_jvetres-2020-0072_s_007_w2aab3b7c67b1b6b1aab1c14b3Aa"><h3>Results</h3><p>All isolates were susceptible to voriconazole. According to the MIC values obtained for amphotericin B and fluconazole, all <italic>Candida</italic> spp. isolates were classified as susceptible according to the described breakpoints except for <italic>C</italic>. <italic>krusei</italic>, which was the only isolate that was amphotericin B-, fluconazole- and itraconazole-resistant. The susceptibility to itraconazole varied: 11 of the <italic>Candida</italic> isolates were susceptible (21.1%), 29 were dose-dependently susceptible (55.8%), and 12 isolates were resistant (23.1%).</p></sec><sec id="j_jvetres-2020-0072_s_008_w2aab3b7c67b1b6b1aab1c14b4Aa"><h3>Conclusion</h3><p>There are few resistant strains of <italic>Candida</italic> in turkeys, and the drug resistance varies. When <italic>Candida</italic> passes from turkeys to humans, there is a wide range of antifungal treatment options.</p></sec></abstract>

IntroductionCandida species are a natural component of the intestinal tract microflora, but in favourable conditions they can cause superficial, mucosal, or even systemic candidiasis. Poultry production might be a source of human drug-resistant yeast infections, including Candida spp. The limited data concerning the antifungal susceptibility of poultry Candida isolates prompted us to carry out research to determine the susceptibility of isolates from turkey intestinal tracts.Method and MaterialsThe beak cavity, crop and cloaca were swabbed of 580 turkeys from 58 flocks in western Poland. The susceptibility tests were conducted using the E-test method with amphotericin B, fluconazole, itraconazole, and voriconazole on 52 isolates of C. albicans, C. catenulata, C. glabrata, C. palmioleophila, C. rugosa, C. krusei and C. lusitaniae.ResultsAll isolates were susceptible to voriconazole. According to the MIC values obtained for amphotericin B and fluconazole, all Candida spp. isolates were classified as susceptible according to the described breakpoints except for C. krusei, which was the only isolate that was amphotericin B-, fluconazole- and itraconazole-resistant. The susceptibility to itraconazole varied: 11 of the Candida isolates were susceptible (21.1%), 29 were dose-dependently susceptible (55.8%), and 12 isolates were resistant (23.1%).ConclusionThere are few resistant strains of Candida in turkeys, and the drug resistance varies. When Candida passes from turkeys to humans, there is a wide range of antifungal treatment options.

E-test determination of antifungal susceptibility of <italic>Candida</italic> species isolated from turkeys

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

E-test determination of antifungal susceptibility of  species isolated from turkeys

IntroductionCandida species are a natural component of the intestinal tract microflora, but in favourable conditions they can cause superficial, mucosal, or...

E-test determination of antifungal susceptibility of Candida species isolated from turkeys

Online veröffentlicht: 10. Nov. 2020

Seitenbereich: 517 - 521

Eingereicht: 14. Mai 2020

Akzeptiert: 26. Okt. 2020

DOI: https://doi.org/10.2478/jvetres-2020-0072

Schlüsselwörter
antimicrobials, E-test, MIC, susceptibility, turkeys

© 2020 I. Sokół et al. published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

E-test determination of antifungal susceptibility of Candida species isolated from turkeys

Online veröffentlicht: 10. Nov. 2020

Seitenbereich: 517 - 521

Eingereicht: 14. Mai 2020

Akzeptiert: 26. Okt. 2020

DOI: https://doi.org/10.2478/jvetres-2020-0072

Schlüsselwörterantimicrobials, E-test, MIC, susceptibility, turkeys

© 2020 I. Sokół et al. published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
antimicrobials, E-test, MIC, susceptibility, turkeys