<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_jvetres-2020-0035_s_005_w2aab3b7b6b1b6b1aab1c14b1Aa"><h3>Introduction</h3><p>Malignant catarrhal fever (MCF) is a rare, under-explored lethal viral infection of cattle with gammaherpesvirus aetiological agents. Most often, the disease occurs on farms where cattle and sheep are kept together. However, other trigger mechanisms and environmental factors contribute. This study investigates the causation of MCF.</p></sec><sec id="j_jvetres-2020-0035_s_006_w2aab3b7b6b1b6b1aab1c14b2Aa"><h3>Material and Methods</h3><p>An outbreak of MCF occurred in June - August 2017 in Kharchev village in Irkutsk Oblast, Russia. In this paper, we provide epidemiological (sanitary status of pastures, watering places, and premises) and weather data during the outbreak, and descriptions of the clinical signs and post-mortem changes in cattle. The virus was detected and isolated from pathological material samples and identified by molecular methods.</p></sec><sec id="j_jvetres-2020-0035_s_007_w2aab3b7b6b1b6b1aab1c14b3Aa"><h3>Results</h3><p>Extreme weather conditions, mixed-herd cattle and sheep farming, and unsatisfactory feed quality contributed to the outbreak. A virus related to herpesvirus OvHV2 was isolated and typed (MCF/Irkutsk/2017). Phylogenetic analysis showed its close genetic relationship to isolates from cattle and sheep in Germany, USA, and the Netherlands.</p></sec><sec id="j_jvetres-2020-0035_s_008_w2aab3b7b6b1b6b1aab1c14b4Aa"><h3>Conclusion</h3><p>Sporadic outbreaks of MCF caused by biotic and abiotic factors together are typical for the Russian Federation, and the Irkutsk outbreak epitomised this. Temperature anomalies caused pasture depletion, resulting in feed and water deficiency for grazing animals and dehydration and acidosis. Heat stress in animals ultimately led to the occurrence of MCF in the herd.</p></sec></abstract>

IntroductionMalignant catarrhal fever (MCF) is a rare, under-explored lethal viral infection of cattle with gammaherpesvirus aetiological agents. Most often, the disease occurs on farms where cattle and sheep are kept together. However, other trigger mechanisms and environmental factors contribute. This study investigates the causation of MCF.Material and MethodsAn outbreak of MCF occurred in June - August 2017 in Kharchev village in Irkutsk Oblast, Russia. In this paper, we provide epidemiological (sanitary status of pastures, watering places, and premises) and weather data during the outbreak, and descriptions of the clinical signs and post-mortem changes in cattle. The virus was detected and isolated from pathological material samples and identified by molecular methods.ResultsExtreme weather conditions, mixed-herd cattle and sheep farming, and unsatisfactory feed quality contributed to the outbreak. A virus related to herpesvirus OvHV2 was isolated and typed (MCF/Irkutsk/2017). Phylogenetic analysis showed its close genetic relationship to isolates from cattle and sheep in Germany, USA, and the Netherlands.ConclusionSporadic outbreaks of MCF caused by biotic and abiotic factors together are typical for the Russian Federation, and the Irkutsk outbreak epitomised this. Temperature anomalies caused pasture depletion, resulting in feed and water deficiency for grazing animals and dehydration and acidosis. Heat stress in animals ultimately led to the occurrence of MCF in the herd.

Malignant catarrhal fever in cattle in the Irkutsk Region

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Malignant catarrhal fever in cattle in the Irkutsk Region"}

IntroductionMalignant catarrhal fever (MCF) is a rare, under-explored lethal viral infection of cattle with gammaherpesvirus aetiological agents. Most often,...

Malignant catarrhal fever in cattle in the Irkutsk Region

Online veröffentlicht: 12. Mai 2020

Seitenbereich: 215 - 222

Eingereicht: 20. Aug. 2019

Akzeptiert: 30. Apr. 2020

DOI: https://doi.org/10.2478/jvetres-2020-0035

Schlüsselwörter
cattle, malignant catarrhal fever, outbreak, clinical signs, climate change, Russia

© 2020 O. Zakharova et al. published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Malignant catarrhal fever in cattle in the Irkutsk Region

Online veröffentlicht: 12. Mai 2020

Seitenbereich: 215 - 222

Eingereicht: 20. Aug. 2019

Akzeptiert: 30. Apr. 2020

DOI: https://doi.org/10.2478/jvetres-2020-0035

Schlüsselwörtercattle, malignant catarrhal fever, outbreak, clinical signs, climate change, Russia

© 2020 O. Zakharova et al. published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
cattle, malignant catarrhal fever, outbreak, clinical signs, climate change, Russia