Detection of Dinophysis species and associated okadaic acid in farmed shellfish: a two-year study from the western Mediterranean area

1 AESAN: EU-Harmonised Standard Operating Procedure for determination of lipophilic marine biotoxins in molluscs by LC-MS/MS. Version 5, 2015, European Union Reference Laboratory for Marine Biotoxins, Agencia Española de Consumo, Seguridad Alimentaria y Nutrición,Vigo, Spain.AESANEU-Harmonised Standard Operating Procedure for determination of lipophilic marine biotoxins in molluscs by LC-MS/MS. Version 5, 2015, European Union Reference Laboratory for Marine Biotoxins, Agencia Española de Consumo, Seguridad Alimentaria y Nutrición,VigoSpainSearch in Google Scholar

2 Ajani P., Brett S., Krogh M., Scanes P., Webster G., Armand L.: The risk of harmful algal blooms (HABs) in the oyster-growing estuaries of New South Wales, Australia. Environ Monit Assess 2013, 185, 5295–5316.AjaniP.BrettS.KroghM.ScanesP.WebsterG.ArmandL.The risk of harmful algal blooms (HABs) in the oyster-growing estuaries of New South Wales, AustraliaEnviron Monit Assess20131855295–531610.1007/s10661-012-2946-923111868Search in Google Scholar

3 Bazzoni A.M., Caddeo T., Pulina S., Padedda B.M., Satta C.T., Sechi N., Lugliè A.: Spatial distribution and multiannual trends of potentially toxic microalgae in shellfish farms along the Sardinian coast (NW Mediterranean Sea). Environ Monit Assess 2015, 187, 1–18.BazzoniA.M.CaddeoT.PulinaS.PadeddaB.M.SattaC.T.SechiN.LuglièA.Spatial distribution and multiannual trends of potentially toxic microalgae in shellfish farms along the Sardinian coast (NW Mediterranean Sea)Environ Monit Assess20151871–1810.1007/s10661-014-4250-325655125Search in Google Scholar

4 Boni L., Mancini L., Milandri A., Poletti R., Pompei M., Viviani R.: First cases of DSP in the Northern Adriatic Sea. International Conference Regione Emilia Romagna, Bologna (Italy), 1990, 419–426.BoniL.ManciniL.MilandriA.PolettiR.PompeiM.VivianiR.First cases of DSP in the Northern Adriatic SeaInternational Conference Regione Emilia Romagna, Bologna (Italy)1990419–426Search in Google Scholar

5 Ciminiello P., Dell’Aversano C., Forino M., Tartaglione L.: Marine toxins in Italy: the more you look, the more you find. Eur J Org Chem 2014, 1990, 1357–1369.CiminielloP.Dell’AversanoC.ForinoM.TartaglioneL.Marine toxins in Italy: the more you look, the more you findEur J Org Chem201419901357–136910.1002/ejoc.201300991Search in Google Scholar

6 Dahl E., Johannessen T.: Relationship between occurrence of Dinophysis species Dinophyceae and shellfish toxicity. Phycologia 2001, 40, 223–227.DahlE.JohannessenT.Relationship between occurrence of Dinophysis species Dinophyceae and shellfish toxicityPhycologia200140223–22710.2216/i0031-8884-40-3-223.1Search in Google Scholar

7 Economou V., Papadopoulou C., Brett M., Kansouzidou A., Charalabopoulos K., Filioussis G., Seferiadis K.: Diarrhetic shellfish poisoning due to toxic mussel consumption: the first record outbreak in Greece. Food Addit Contam 2007, 24, 297–305.EconomouV.PapadopoulouC.BrettM.KansouzidouA.CharalabopoulosK.FilioussisG.SeferiadisK.Diarrhetic shellfish poisoning due to toxic mussel consumption: the first record outbreak in GreeceFood Addit Contam200724297–30510.1080/0265203060105313917364933Search in Google Scholar

8 European Commission: Regulation of 26 November 1996, 2406/19964/EC. OJ L 334, 23/12/1996.European Commission: Regulation of 26 November 1996, 2406/19964/EC. OJ L 334, 23/12/1996Search in Google Scholar

9 European Commission: Regulation of 29 April 2004, 853/2004/EC. OJ L 139, 30/04/2004.European Commission: Regulation of 29 April 2004, 853/2004/EC. OJ L 139, 30/04/2004Search in Google Scholar

10 European Commission: Regulation of 10 January 2011, 15/2011/EC. OJ L 6, 10/01/2011.European Commission: Regulation of 10 January 2011, 15/2011/EC. OJ L 6, 10/01/201110.32964/TJ10.1Search in Google Scholar

11 Fabro E., Almandoz G.O., Ferrario M., Tillmann U., Cembella A., Krock B.: Distribution of Dinophysis species and their association with lipophilic phycotoxins in plankton from the Argentine Sea. Harmful Algae 2016, 59, 31–41.FabroE.AlmandozG.O.FerrarioM.TillmannU.CembellaA.KrockB.Distribution of Dinophysis species and their association with lipophilic phycotoxins in plankton from the Argentine SeaHarmful Algae20165931–4110.1016/j.hal.2016.09.00128073504Search in Google Scholar

12 Godhe A., Svensson S., Rehnstam-Holm A.S.: Oceanographic settings explain fluctuations in Dinophysis spp. and concentrations of diarrhetic shellfish toxin in the plankton community within a mussel farm area on the Swedish west coast. Mar Ecol Prog Ser 2002, 240, 71–83.GodheA.SvenssonS.Rehnstam-HolmA.S.Oceanographic settings explain fluctuations in Dinophysis sppand concentrations of diarrhetic shellfish toxin in the plankton community within a mussel farm area on the Swedish west coast. Mar Ecol Prog Ser200224071–8310.3354/meps240071Search in Google Scholar

13 Hossen V., Jourdan-da Silva N., Guillois-Bécel Y., Marchal J., Krys S.: Food poisoning outbreaks linked to mussels contaminated with okadaic acid and ester dinophysistoxin-3 in France, June 2009. Eurosurveillance 2011, 16, 1–7.HossenV.Jourdan-daSilva N.Guillois-BécelY.MarchalJ.KrysS.Food poisoning outbreaks linked to mussels contaminated with okadaic acid and ester dinophysistoxin-3 in France, June 2009Eurosurveillance2011161–710.2807/ese.16.46.20020-en22115047Search in Google Scholar

14 Intergovernmental Oceanographic Commission (IOC-UNESCO): Taxonomic Reference List of Harmful Micro Algae. http://www.marinespecies.org/habIntergovernmental Oceanographic Commission (IOC-UNESCO): Taxonomic Reference List of Harmful Micro Algaehttp://www.marinespecies.org/habSearch in Google Scholar

15 James K.J., Carey B., O’Halloran J., van Pelt F.N.A.M., Skrabakova Z.: Shellfish toxicity: human health implications of marine algal toxins. Epidemiol Infect 2010, 138, 927–940.JamesK.J.CareyB.O’HalloranJ.vanPelt F.N.A.M.SkrabakovaZ.Shellfish toxicity: human health implications of marine algal toxinsEpidemiol Infect2010138927–94010.1017/S095026881000085320412612Search in Google Scholar

16 Koukaras K., Nikolaidis G.: Dinophysis blooms in Greek coastal waters (Thermaikos Gulf, NW Aegean Sea). J Plankton Res 2004, 26, 445–457.KoukarasK.NikolaidisG.Dinophysis blooms in Greek coastal waters (Thermaikos Gulf, NW Aegean Sea)J Plankton Res200426445–45710.1093/plankt/fbh042Search in Google Scholar

17 Lorenzoni G., Arras I., Sanna G., Delogu P., Mudadu A., Piras A., Mura A., Marongiu E., Virgilio S.: Paralytic shellfish poison algal biotoxins: Sardinia report 2002–2011 and non-compliance management. Ital J Food Saf 2013, 2, 104–108.LorenzoniG.ArrasI.SannaG.DeloguP.MudaduA.PirasA.MuraA.MarongiuE.VirgilioS.Paralytic shellfish poison algal biotoxins: Sardinia report 2002–2011 and non-compliance managementItal J Food Saf20132104–10810.4081/ijfs.2013.e30Search in Google Scholar

18 Lugliè A., Satta C.T., Pulina S., Bazzoni A.M., Padedda B.M., Sechi N.: Harmful algal blooms in Sardinia. Biol Mar Medit 2011, 18, 2–9.LuglièA.SattaC.T.PulinaS.BazzoniA.M.PadeddaB.M.SechiN.Harmful algal blooms in SardiniaBiol Mar Medit2011182–9Search in Google Scholar

19 Moita M.T., Pazos Y., Rocha C., Nolasco R., Oliveira P.B.: Toward predicting Dinophysis blooms off NW Iberia: a decade of events. Harmful Algae 2016, 53, 17–32.MoitaM.T.PazosY.RochaC.NolascoR.OliveiraP.B.Toward predicting Dinophysis blooms off NW Iberia: a decade of eventsHarmful Algae20165317–3210.1016/j.hal.2015.12.00228073442Search in Google Scholar

20 Naustvoll L.J., Gustad E., Dahl E.: Monitoring of Dinophysis species and diarrhetic shellfish toxins in Flødevigen Bay, Norway: inter-annual variability over a 25-year time series. Food Addit Contam 2012, 29, 1605–1615.NaustvollL.J.GustadE.DahlE.Monitoring of Dinophysis species and diarrhetic shellfish toxins in Flødevigen Bay, Norway: inter-annual variability over a 25-year time seriesFood Addit Contam2012291605–161510.1080/19440049.2012.71490822891979Search in Google Scholar

21 Padedda B.M., Pulina S., Magni P., Sechi N., Lugliè A.: Phytoplankton dynamics in relation to environmental changes in a phytoplankton-dominated Mediterranean lagoon (Cabras Lagoon, Italy). AIOL J 2012, 3, 147–169.PadeddaB.M.PulinaS.MagniP.SechiN.LuglièA.Phytoplankton dynamics in relation to environmental changes in a phytoplankton-dominated Mediterranean lagoon (Cabras Lagoon, Italy)AIOL J20123147–16910.1080/19475721.2012.716792Search in Google Scholar

22 Reguera B., Pizarro G.: Planktonic dinoflagellates that contain polyether toxins of the old ‘‘DSP complex’’. In: Seafood and Freshwater Toxins. Pharmacology, Physiology, and Detection edited by L.M. Botana, CRC Press, Boca Raton, 2008, pp. 257–284.RegueraB.PizarroG.Planktonic dinoflagellates that contain polyether toxins of the old ‘‘DSP complex’’InSeafood and Freshwater Toxins. Pharmacology, Physiology, and Detectionedited byx L.M. BotanaCRC Press, Boca Raton2008pp257–28410.1201/9781420007541.pt6Search in Google Scholar

23 Reguera B., Riobó P., Rodríguez F., Díaz P.A., Pizarro G., Paz B., Franco J.M., Blanco J.: Dinophysis toxins: causative organisms, distribution and fate in shellfish. Mar Drugs 2014, 12, 394–461.RegueraB.RiobóP.RodríguezF.DíazP.A.PizarroG.PazB.FrancoJ.M.BlancoJ.Dinophysis toxins: causative organisms, distribution and fate in shellfishMar Drugs201412394–46110.3390/md12010394391728024447996Search in Google Scholar

24 Reguera B., Velo-Suárez L., Raine R., Park M.G.: Harmful Dinophysis species: a review. Harmful Algae 2012, 14, 87–106.RegueraB.Velo-SuárezL.RaineR.ParkM.G.Harmful Dinophysis species: a reviewHarmful Algae20121487–10610.1016/j.hal.2011.10.016Search in Google Scholar

25 Sannio A., Lugliè A., Sechi N.: Potentially toxic dinoflagellates in Sardinia. Plant Biosyst 1997, 131, 73–78.SannioA.LuglièA.SechiN.Potentially toxic dinoflagellates in SardiniaPlant Biosyst199713173–7810.1080/11263504.1997.10654169Search in Google Scholar

26 Sardinia Region: Regional plan for the surveillance and sanitary control of the production and marketing of live bivalve molluscs and for the periodic monitoring of production areas of live bivalve molluscs (123 pp.), 2015, Regione Sardegna, Italy (Regulation in Italian).Sardinia Region: Regional plan for the surveillance and sanitary control of the production and marketing of live bivalve molluscs and for the periodic monitoring of production areas of live bivalve molluscs (123 pp.), 2015, Regione Sardegna, Italy (Regulation in Italian)Search in Google Scholar

27 Turki S., Dhib A., Fertouna-Bellakhal M., Frossard V., Balti N., Kharrat R., Aleya L.: Harmful algal blooms (HABs) associated with phycotoxins in shellfish: What can be learned from five years of monitoring in Bizerte Lagoon (Southern Mediterranean Sea)? Ecol Eng 2014, 67, 39–47.TurkiS.DhibA.Fertouna-BellakhalM.FrossardV.BaltiN.KharratR.AleyaL.Harmful algal blooms (HABs) associated with phycotoxins in shellfish: What can be learned from five years of monitoring in Bizerte Lagoon (Southern Mediterranean Sea)? Ecol Eng20146739–4710.1016/j.ecoleng.2014.03.028Search in Google Scholar

28 Utermöhl H.: Zur vervollkommung der quantitativen phytoplankton-methodik. Verh Int Verein Theor Angew Limnol 1958, 9, 1–39.UtermöhlH.Zur vervollkommung der quantitativen phytoplankton-methodikVerh Int Verein Theor Angew Limnol195891–3910.1080/05384680.1958.11904091Search in Google Scholar

29 Van der Fels-Klerx H.J., Adamse P., Goedhart P.W., Poelman M., Pol-Hofstad I.E., van Egmond H., Gerssen A.: Monitoring phytoplankton and marine biotoxins in production waters of the Netherlands: results after one decade. Food Addit Contam 2012, 29, 1616–1629.Vander Fels-Klerx H.J.AdamseP.GoedhartP.W.PoelmanM.Pol-HofstadI.E.vanEgmond H.GerssenA.Monitoring phytoplankton and marine biotoxins in production waters of the Netherlands: results after one decadeFood Addit Contam2012291616–162910.1080/19440049.2011.62834022067064Search in Google Scholar

30 Villalobos L.G., Santinelli N., Sastre V., Krock B., Esteves J.L.: Dinophysis species associated with diarrhetic shellfish poisoning episodes in North Patagonian Gulfs (Chubut, Argentina). J Shellfish Res 2015, 34, 1141–1149.VillalobosL.G.SantinelliN.SastreV.KrockB.EstevesJ.L.Dinophysis species associated with diarrhetic shellfish poisoning episodes in North Patagonian Gulfs (Chubut, Argentina)J Shellfish Res2015341141–114910.2983/035.034.0339Search in Google Scholar