<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Nonhuman primates are often used in biomedical research and to investigate physiologic processes that occur in man. Impedance plethysmography was used to measure calf, thigh, pelvic, abdominal, and thoracic volume changes in ten Rhesus and eight squirrel monkeys during five-minute exposures to HUT and HDT at angles of 5, 10, and 20 degrees. Calf, rump and tail measurements were made in three squirrel monkeys at 10 and 20 degrees of HUT and HDT. Fluid volume changes in all segments of the Rhesus monkeys were found to change during HUT an HDT in direct relation to the angle of tilt used. However, the volume changes that occurred in the squirrel monkeys were found to be quite different. Their calf, thigh, and pelvic segments <underline>lost</underline> volume during <underline>both</underline> HUT and HDT while their abdominal and thoracic segments responded similarly to those of the Rhesus monkeys. These results and those of the calf/tail measurements of the squirrel monkeys suggest that they may utilize their tails as a compensatory reservoir during postural changes and therefore, may not be an appropriate animal model for man under some orthostatic test conditions.</p>
</abstract>

Nonhuman primates are often used in biomedical research and to investigate physiologic processes that occur in man. Impedance plethysmography was used to measure calf, thigh, pelvic, abdominal, and thoracic volume changes in ten Rhesus and eight squirrel monkeys during five-minute exposures to HUT and HDT at angles of 5, 10, and 20 degrees. Calf, rump and tail measurements were made in three squirrel monkeys at 10 and 20 degrees of HUT and HDT. Fluid volume changes in all segments of the Rhesus monkeys were found to change during HUT an HDT in direct relation to the angle of tilt used. However, the volume changes that occurred in the squirrel monkeys were found to be quite different. Their calf, thigh, and pelvic segments lost volume during both HUT and HDT while their abdominal and thoracic segments responded similarly to those of the Rhesus monkeys. These results and those of the calf/tail measurements of the squirrel monkeys suggest that they may utilize their tails as a compensatory reservoir during postural changes and therefore, may not be an appropriate animal model for man under some orthostatic test conditions.

Segmental volume changes that occur in nonhuman primates during short term head up (HUT) and head down (HDT) tilt

Journal of Electrical Bioimpedance

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Nonhuman primates are often used in biomedical research and to investigate physiologic processes that occur in man. Impedance plethysmography was used to...

0 – 5 min.	Horizontal
5 – 10 min.	HUT or HDT at 10 deg.
10 – 15 min.	Horizontal
15 – 20 min.	HUT or HDT at 20 deg.
20 – 25 min.	Horizontal.

Position	Elapsed time (min)	Time at position (min)
Flat	5	5
+5	10	5
Flat	15	5
+10	20	5
Flat	25	5
+20	30	5
Flat	35	5

Segmental volume changes that occur in nonhuman primates during short term head up (HUT) and head down (HDT) tilt

Online veröffentlicht: 18. März 2020

Seitenbereich: 12 - 18

Eingereicht: 04. Feb. 2020

DOI: https://doi.org/10.2478/joeb-2020-0003

Schlüsselwörter
Bioimpedance, Monkeys, Head-up tilt, Head-down tilt

© 2019 Leslie David Montgomery et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Figure 2

Figure 3

j.joeb-2020-0003.tab.002

j.joeb-2020-0003.tab.001

Segmental volume changes that occur in nonhuman primates during short term head up (HUT) and head down (HDT) tilt

Online veröffentlicht: 18. März 2020

Seitenbereich: 12 - 18

Eingereicht: 04. Feb. 2020

DOI: https://doi.org/10.2478/joeb-2020-0003

SchlüsselwörterBioimpedance, Monkeys, Head-up tilt, Head-down tilt

© 2019 Leslie David Montgomery et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Figure 2

Figure 3

j.joeb-2020-0003.tab.002

j.joeb-2020-0003.tab.001

Schlüsselwörter
Bioimpedance, Monkeys, Head-up tilt, Head-down tilt