<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Coronary computed tomography angiography (CCTA) is a reliable screening method of patients with coronary artery disease (CAD). CCTA is capable to assess both coronary stenosis and plaque morphology, but does not provide hemodynamic characterization of the coronary lesions. However, the severity of coronary stenosis does not always reflect the hemodynamic significance of the plaque. Invasive fractional flow reserve (FFR) is considered the gold standard for the functional evaluation of a potential ischemia-causing stenosis. FFR derived from CCTA (FFR-CT) is a new noninvasive diagnostic tool, using a typically acquired CCTA, without the need for any further radiation or medication. Additional functional assessment of the coronary lesions permits a more complex characterization of CAD patients. Based on the FFR-CT examination, patients who need invasive coronary intervention can be selected more precisely, and a more personalized and optimized treatment can be provided.</p>
</abstract>

Coronary computed tomography angiography (CCTA) is a reliable screening method of patients with coronary artery disease (CAD). CCTA is capable to assess both coronary stenosis and plaque morphology, but does not provide hemodynamic characterization of the coronary lesions. However, the severity of coronary stenosis does not always reflect the hemodynamic significance of the plaque. Invasive fractional flow reserve (FFR) is considered the gold standard for the functional evaluation of a potential ischemia-causing stenosis. FFR derived from CCTA (FFR-CT) is a new noninvasive diagnostic tool, using a typically acquired CCTA, without the need for any further radiation or medication. Additional functional assessment of the coronary lesions permits a more complex characterization of CAD patients. Based on the FFR-CT examination, patients who need invasive coronary intervention can be selected more precisely, and a more personalized and optimized treatment can be provided.

Noninvasive Functional Characterization of Coronary Plaques by Coronary Computed Tomography – Beyond the Morphology of Vulnerable Plaques

University of Medicine, Pharmacy, Science and Technology

Journal of Interdisciplinary Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Coronary computed tomography angiography (CCTA) is a reliable screening method of patients with coronary artery disease (CAD). CCTA is capable to assess both...

Noninvasive Functional Characterization of Coronary Plaques by Coronary Computed Tomography – Beyond the Morphology of Vulnerable Plaques

Online veröffentlicht: 12. Nov. 2019

Seitenbereich: 132 - 135

Eingereicht: 16. Juli 2019

Akzeptiert: 31. Aug. 2019

DOI: https://doi.org/10.2478/jim-2019-0022

Schlüsselwörter
coronary computed tomography angiography, coronary artery disease, invasive fractional flow reserve

© 2019 Zsolt Parajkó et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Noninvasive Functional Characterization of Coronary Plaques by Coronary Computed Tomography – Beyond the Morphology of Vulnerable Plaques

Online veröffentlicht: 12. Nov. 2019

Seitenbereich: 132 - 135

Eingereicht: 16. Juli 2019

Akzeptiert: 31. Aug. 2019

DOI: https://doi.org/10.2478/jim-2019-0022

Schlüsselwörtercoronary computed tomography angiography, coronary artery disease, invasive fractional flow reserve

© 2019 Zsolt Parajkó et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
coronary computed tomography angiography, coronary artery disease, invasive fractional flow reserve