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<p>Gestational hypertension and preeclampsia complicate 2–8% of pregnancies, with a great impact on the fetuses, as well as on maternal well-being. Preeclampsia is considered a major cardiovascular emergency due to its potential to evolve to severe eclampsia, a devastating life-threatening condition. Worldwide, preeclampsia is considered to be one of the major factors that lead to maternal and fetal death. On average, hypertensive disorders are responsible for approximately 16% of maternal deaths, and every year, preeclampsia is estimated to cause more than 500,000 deaths of the fetus and 70,000 maternal deaths all over the world. While different studies published so far have not succeeded in identifying the exact mechanisms that cause preeclampsia, ischemic vascular phenomena, immunological disorders, and inflammation have been reported as important factors involved in its pathogenesis. The current review aims to provide updated, relevant literature data regarding the potential link between elevated inflammatory status and preeclampsia, at the same time underlining the role of emerging imaging techniques for the early detection of preeclamptic risk.</p>
</abstract>

Gestational hypertension and preeclampsia complicate 2–8% of pregnancies, with a great impact on the fetuses, as well as on maternal well-being. Preeclampsia is considered a major cardiovascular emergency due to its potential to evolve to severe eclampsia, a devastating life-threatening condition. Worldwide, preeclampsia is considered to be one of the major factors that lead to maternal and fetal death. On average, hypertensive disorders are responsible for approximately 16% of maternal deaths, and every year, preeclampsia is estimated to cause more than 500,000 deaths of the fetus and 70,000 maternal deaths all over the world. While different studies published so far have not succeeded in identifying the exact mechanisms that cause preeclampsia, ischemic vascular phenomena, immunological disorders, and inflammation have been reported as important factors involved in its pathogenesis. The current review aims to provide updated, relevant literature data regarding the potential link between elevated inflammatory status and preeclampsia, at the same time underlining the role of emerging imaging techniques for the early detection of preeclamptic risk.

Inflammation, Gestational Hypertension, and Preeclampsia – a Dangerous Association

“George Emil Palade” University of Medicine, Pharmacy, Science and Technology

“Grigore T. Popa” University of Medicine and Pharmacy

Journal of Cardiovascular Emergencies

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Gestational hypertension and preeclampsia complicate 2–8% of pregnancies, with a great impact on the fetuses, as well as on maternal well-being. Preeclampsia...

Inflammation, Gestational Hypertension, and Preeclampsia – a Dangerous Association

Online veröffentlicht: 10. Apr. 2023

Seitenbereich: 1 - 8

Eingereicht: 18. Dez. 2022

Akzeptiert: 29. Jan. 2023

DOI: https://doi.org/10.2478/jce-2023-0002

Schlüsselwörter
preeclampsia, gestational hypertension, maternal and fetal mortality, inflammation, pregnancy-related cardiovascular emergency

© 2023 Alina-Georgiana Corduneanu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Inflammation, Gestational Hypertension, and Preeclampsia – a Dangerous Association

Online veröffentlicht: 10. Apr. 2023

Seitenbereich: 1 - 8

Eingereicht: 18. Dez. 2022

Akzeptiert: 29. Jan. 2023

DOI: https://doi.org/10.2478/jce-2023-0002

Schlüsselwörterpreeclampsia, gestational hypertension, maternal and fetal mortality, inflammation, pregnancy-related cardiovascular emergency

© 2023 Alina-Georgiana Corduneanu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
preeclampsia, gestational hypertension, maternal and fetal mortality, inflammation, pregnancy-related cardiovascular emergency