Uneingeschränkter Zugang

Aberrant Crypt Foci - Endpoint in Colorectal Cancer

   | 06. Jan. 2024

Zitieren

Morin, P., Sparks, A., Korinek, V., Barker, N., et al(1997) activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science, 275; 1787-1790. Search in Google Scholar

Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. N Engl J Med 1988; 319: 525–532 Search in Google Scholar

Smith KJ, Johnson KA, Bryan TM, et al. The APC gene product in normal and tumor cells. Proc Natl Acad Sci U S A 1993; 90: 2846–2850. Search in Google Scholar

Miyashiro I, Senda T, Matsumine A, et al. Subcellular localization of the APC protein: immunoelectron microscopic study of the association of the APC protein with catenin. Oncogene 1995; 11: 89–96 Search in Google Scholar

Lynch HT, Smyrk T, Lynch JF. Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch Syndrome). Int J Cancer 1996; 69: 38–43. Search in Google Scholar

Bhattacharyya NP, Skandalis A, Ganesh A, et al. Mutator phenotypes in human colorectal carcinoma cell lines. Proc Natl Acad Sci U S A 1994; 91: 6319–6323 Search in Google Scholar

Lynch, JP, Hoops, TC. The genetic pathogenesis of colorectal cancer. Hematol Oncol Clin North Am 2002; 16:775 Search in Google Scholar

Eshleman JR, Lang EZ, Bowerfind GK, et al. Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer. Oncogene 1995; 10: 33–37. Search in Google Scholar

Shibata D, Peinado MA, Ionov Y, et al. Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation. Nat Genet 1994; 6: 273–281 Search in Google Scholar

Pretlow TP, O Riordan MA, Pretlow TG, Stellato TA. Abberant crypts in human colonic mucosa:putative preneoplastic lesions. J Cell Biochem 1992;16G:55-62. Search in Google Scholar

Takayama T, Katsuki Y, Oho M et al. Aberrant crypt foci of the colon as precursors of adenoma and cancer. N Engl J Med 1998;339;1277-84. Search in Google Scholar

Yamada Y, Yoshimi N, Hirose Y et al. Frequent bcatenin gene mutations and accumulations of the protein in the putative preneoplastic lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis. Cancer Res 2000;60;3323-7. Search in Google Scholar

Caderni G, femia AP, Giannini A, et al. Identification of mucin depleted foci in the unsectioned colon of azoxymethane-treated rats: correlation with carcinogenesis. Cancer Res 2003; 63:2388-92. Search in Google Scholar

Femia AP, Giannini A, fazi M,et al. Identification of mucin depleted foci in the human colon. Cancer Prev Rev 2008;1:562-7. Search in Google Scholar

Mori H, Hata K, Yamada Y, Kuno T, Hara A. Significance and role of early – lesions in axperimental coloractal carcinogenesis. Chem Biol Interact 2005;155:1-9. Search in Google Scholar

Bird RP, Good CK. The significance of aberant crypt foci in understanding the pathogenesis of colon cancer. Toxicol Lett 2000;112/113:395-402. Search in Google Scholar

Kudo S., Hirota S., et al. Colorectal tumors and pit pattern. J. Clin. Pathol., 1994;47:880-885. Search in Google Scholar

Kudo S., Rubio C.A., Teixeira C.R., and Kogue E. Pit pattern in colorectal neoplasia:endoscopic magnifying view. Endoscopy 2001;33:367-373. Search in Google Scholar

Hamilton S., and Aaltonen L. Tumors of Digestive System 2000;IARC Sientific Press, IARC, Lyon. Search in Google Scholar

Riggleman B., Scheld P.,and Wieschaus E. Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless. Cell, 1990;63:549-560. Search in Google Scholar

Hart M., Concordet J.P., Lassot I.,et al. The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell. Curr. Bio, 1999;9:207-210. Search in Google Scholar

Aberle H., Bauer A., Stappert J.,and Kemler R. Beta –catenin is a target for the ubiquitin-proteasone pathway. EMBO J., 1997;16:3797-3804. Search in Google Scholar

He T., Sparks A., Vogelstein B., and Kinzler K. Constitutive transcriptional activation by a beta-carenin-Tcf complex in APC-carcinoma. Science, 1997;275:1784-1787. Search in Google Scholar

Tetsu O., and McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature, 1999;281:1509-1512. Search in Google Scholar

Vogelstein B., and Kinzler K. The genetic Basis of Human Cancer.1998. McGraw-Hill, New York. Search in Google Scholar

Takahashi M., Fuduka K., and Wakabayashi K. Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res., 1998;58:42-46. Search in Google Scholar

Yamada Y., Yoshimi N., Hirose Y, et al. Sequential analysis of morphological and biological properties of beta-catenin-acumulated crypts,probable premalignant lesions independent of aberrant crypt foci in rat colon carcinogenesis. Cancer Rev 2001;61:1874-1878. Search in Google Scholar

Yamada Y., Yoshimi N., Hara A., and Mori H. Frequent beta-catenin gene mutations and accumulations of the protein in the putative pre-neoplastic lesions lacking macroscopic abberant crypt foci appearance, in rat colon carcinogenesis. Cancer Res., 2000;60:3323-3327. Search in Google Scholar

Wilson CL., Heppner KJ., and Matrisian L.M. Intestinal tumorigenesis is suppressed in mice laking the metalloproteinase matrilysin. Proc. Natl. Acad. Sci. USA 1997;94:1402-1407. Search in Google Scholar

Yamada Y., Oyama T.,and Mori H. Beta-catenin mutation is selectedduring malignant transformation in colon carcinogenesis. Carcinogenesis, 2003;24:91-97. Search in Google Scholar

Johnson L., Mercer K.,and Jacks T. Somatic activation of the K-ras oncogene causes early onset lung cancer in mice. Nature, 2001;410:1111-1116. Search in Google Scholar

Delapierre, F. et al. (1981) Preneoplastic changes in epithelium and mesenchyme in colon of rats treated with 1,2-dimethylhydrazine. Cancer Detect. Prev., 4, 429–437. Search in Google Scholar

Wargovich, M.J. et al. (1983) Early histopathologic events to evolution of colon cancer in C57BL/6 and CF1 mice treated with 1,2-dimethylhydrazine. J. Natl Cancer Inst., 71, 125–31. Search in Google Scholar

Bird, R.P. (1987) Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett., 37, 147–151. Search in Google Scholar

Pretlow, T.P. et al. (1993) Two types of putative preneoplastic lesions identified by hexosaminidase activity in whole mounts of colons from F344 rats treated with carcinogen. Am. J. Pathol., 142, 1695–1700. Search in Google Scholar

Tsukamoto, T. et al. (2001) Hexosaminidase-altered aberrant crypts, carrying decreased hexosaminidase alpha and beta subunit mRNAs, in colon of 1,2-dimethylhydrazine-treated rats. Jpn. J. Cancer Res., 92, 109–118. Search in Google Scholar

Tsukamoto, T. et al. (2006) Three-dimensional analysis of isolated hexosaminidase-altered aberrant crypts from colons of 1,2-dimethylhydrazinetreated rats. Exp. Toxicol. Pathol., 57, 283–289. Search in Google Scholar

Hata, K. et al. (2004) Tumor formation is correlated with expression of beta-catenin-accumulated crypts in azoxymethane-induced colon carcinogenesis in mice. Cancer Sci., 95, 316–320. Search in Google Scholar

Caderni, G. et al. (2003) Identification of mucin-depleted foci in the unsanctioned colon of azoxymethane-treated rats: correlation with carcinogenesis. Cancer Res., 63, 2388–2392. Search in Google Scholar

Paulsen, J.E. et al. (2000) Identification and quantification of aberrant crypt foci in the colon of Min mice—a murine model of familial adenomatous polyposis. Scand. J. Gastroenterol., 35, 534–539. Search in Google Scholar

eISSN:
1220-5818
Sprache:
Englisch
Zeitrahmen der Veröffentlichung:
4 Hefte pro Jahr
Fachgebiete der Zeitschrift:
Medizin, Klinische Medizin, Allgemeinmedizin, Innere Medizin, andere, Kardiologie, Gastroenterologie, Pneumologie