Liver Steatosis and its Implications in Patients with Chronic Viral Hepatitis C

1 Adinolfi L E, Gambardella M, Andreana A.et al Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity. Hepatology 2001331358–1364. Search in Google Scholar

2 Clark J M, Brancati F L, Diehl A M. Nonalcoholic fatty liver disease. Gastroenterology 20021221649–1657. Search in Google Scholar

3 Imbert-Bismut F, Ratziu V, Pieroni L, et al. Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Lancet 2001;357(9262):1069–75. Search in Google Scholar

4 Byrne CD, Targher G. NAFLD: a multisystem disease. J Hepatol. 2015;62(1Suppl):S47–64. Search in Google Scholar

5 Bochud PY, Cai T, Overbeck K, et al. Genotype 3 is associated with 2009;51(4):655–66. Search in Google Scholar

6 Kralj D, Virovic Jukic L, Stojsavljevic S, et al. Hepatitis C Virus, Insulin Resistance, and Steatosis. J Clin Translational Hepatol. 2016;4(1):66–75. Search in Google Scholar

7 Seronello S, Ito C, Wakita T, Choi J. Ethanol enhances hepatitis C virus replication through lipid metabolism and elevated NADH/NAD+. J Biol Chem. 2010;285(2): 845–54. Search in Google Scholar

8 Del Campo JA, Romero-Gomez M. Steatosis and insulin resistance in hepatitis C: a way out for the virus? World J Gastroenterol. 2009;15(40):5014–9. Search in Google Scholar

9 Rubbia-Brandt L, Quadri R, Abid K, et al. Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3. J Hepatol. 2000;33(1):106–15. Search in Google Scholar

10 Chitturi S, Farrell G C. Etiopathogenesis of nonalcoholic steatohepatitis. Semin Liver Dis 20012127–41. Search in Google Scholar

11 Rubbia-Brandt L, Giostra E, Mentha G, Quadri R, Negro F. Expression of liver steatosis in hepatitis C virus infection and pattern of response to alphainterferon. J Hepatol. 2001;35(2):307. Search in Google Scholar

12 Bochud PY, Cai T, Overbeck K, et al. Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C. J Hepatol. 2009;51(4):655–66. Search in Google Scholar

13 Sanyal A J. AGA technical review on nonalcoholic fatty liver disease. Gastroenterology 20021231705–1725 Search in Google Scholar

14 Meissner EG, Lee YJ, Osinusi A, et al. Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients. Hepatology (Baltimore, Md). 2015;61(3):790–801. Search in Google Scholar

15 Lee JH, Kim D, Kim HJ, et al. Hepatic steatosis index: a simple screening tool reflecting nonalcoholic fatty liver disease. Dig Liver Dis 2010;42:503–508. Search in Google Scholar