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Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance

E. Karamitrousis

E. Karamitrousis

University Medical Oncology Department, Medical School, Democritus University of ThraceAlexandroupolis, Greece
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Karamitrousis, E.
, 
I. Balgkouranidou

I. Balgkouranidou

University Medical Oncology Department, Medical School, Democritus University of ThraceAlexandroupolis, Greece
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Balgkouranidou, I.
, 
N. Xenidis

N. Xenidis

University Medical Oncology Department, Medical School, Democritus University of ThraceAlexandroupolis, Greece
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Xenidis, N.
, 
K. Amarantidis

K. Amarantidis

University Medical Oncology Department, Medical School, Democritus University of ThraceAlexandroupolis, Greece
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Amarantidis, K.
, 
E. Biziota

E. Biziota

University Medical Oncology Department, Medical School, Democritus University of ThraceAlexandroupolis, Greece
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Biziota, E.
, 
T. Koukaki

T. Koukaki

University Medical Oncology Department, Medical School, Democritus University of ThraceAlexandroupolis, Greece
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Koukaki, T.
 und 
S. Kakolyris

S. Kakolyris

University Medical Oncology Department, Medical School, Democritus University of ThraceAlexandroupolis, Greece
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Kakolyris, S.
  
07. Mai 2022
Concentration of circulating tumour DNA in patients with metastatic gastric cancer and its prognostic significance's Cover Image
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Artikel-Kategorie: Research Article
Online veröffentlicht: 07. Mai 2022
Seitenbereich: 72 - 76
Eingereicht: 14. Okt. 2021
Akzeptiert: 23. Dez. 2021
DOI: https://doi.org/10.2478/fco-2021-0010
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© 2021 Karamitrousis E. et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Gastric cancer is one of the most common cancers worldwide. The amount of cell-free DNA (cfDNA) in the blood of patients with gastric cancer was found to be higher than that of healthy controls (69.1 ng/μL vs. 34.8 ng/μL). Patients with cfDNA ≤ 50 ng/μL were found to have an increased overall survival (OS) and progression free survival (PFS) than in patients with cfDNA > 50 ng/μL.

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