[
Almulla M. Location-based expert system for diabetes diagnosis and medication recommendation. Kuwait J Sci 48, 67–77, 2021.10.48129/kjs.v48i1.8687
]Search in Google Scholar
[
Al-Sulaiti H, Diboun I, Agha MV, Mohamed FFS, Atkin S, Domling AS. Metabolic signature of obesity-associated insulin resistance and type 2 diabetes. J Transl Med 17, 348, 2019.10.1186/s12967-019-2096-8680529331640727
]Search in Google Scholar
[
American Diabetes Association. Standards of medical care in diabetes–2019 abridged for primary care providers. Clin Diabetes 37, 11–34, 2019.10.2337/cd18-0105633611930705493
]Search in Google Scholar
[
Arikoglu H, Aksoy HM, Erkoc KD, Asik A, Ipekci SH, Iscioglu F. IRS1 gene polymorphisms Gly972Arg and Ala-513Pro are not associated with insulin resistance and type 2 diabetes risk in non-obese Turkish population. Meta Gene 2, 579–585, 2014.10.1016/j.mgene.2014.07.008428784825606440
]Search in Google Scholar
[
Bedair RN, Magour GM, Ooda SA, Amar EM, Awad AM. Insulin receptor substrate-1 G972R single nucleotide polymorphism in Egyptian patients with chronic hepatitis C virus infection and type 2 diabetes mellitus. Egypt Liver Journal 11, 2, 2021.10.1186/s43066-020-00069-1
]Search in Google Scholar
[
Bluher M, Stumvoll M. Diabetes and Obesity. In: Diabetes Complications, Comorbidities and Related Disorders (Bonora E, De Fronzo R. Ed.), Endocrinology, Springer, Cham, 2018.10.1007/978-3-319-44433-8_1
]Search in Google Scholar
[
Chernatska O, Demikhova N, Rudenko T, Demikhov A. Assessment of the lipid profile correction in patients with arterial hypertension and type 2 diabetes mellitus. Azer MJ, 1, 18–22, 2019.
]Search in Google Scholar
[
Christiansen E, Urban C, Merten N, Liebscher K, Karlsen KK, Hamacher A. Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes. J Med Chem 51, 7061–7064, 2008.10.1021/jm801017818947221
]Search in Google Scholar
[
Conwell DL, Lee LS, Yadav D, Longnecker DS, Miller FH, Morteleet KJ. American Pancreatic Association Practice Guidelines in Chronic Pancreatitis: evidence-based report on diagnostic guidelines. Pancreas 43, 1143–1162, 2014.10.1097/MPA.0000000000000237543497825333398
]Search in Google Scholar
[
Copps KD, White MF. Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2. Diabetologia 55, 2565–2582, 2012.10.1007/s00125-012-2644-8401149922869320
]Search in Google Scholar
[
Cosentino F, Grant PJ, Aboyans V, et al. 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. Eur Heart 41, 255–323, 2020.
]Search in Google Scholar
[
Degen AS, Krynytska IY, Kamyshnyi AM. Changes in the transcriptional activity of the entero-insular axis genes in streptozotocin-induced diabetes and after the administration of TNF-alpha non-selective blockers. Endocr Regul 54, 160–171, 2020.10.2478/enr-2020-001932857721
]Search in Google Scholar
[
Demihova N, Lidiya C, Chernatska O, Mazur T, Aleksakhina T, Demikhov O. The relationship between lipid metabolism and the level of albuminuria with single nucleotide polymorphism -204A>C [rs 3808607] CYP7A1 gene in patients with type 2 diabetes mellitus and diabetic nephropathy. Rom J Diabet Nutr Metab Dis 26, 253–260, 2019.10.2478/rjdnmd-2019-0026
]Search in Google Scholar
[
Frangioudakis G, Ye JM, Cooney GJ. Both saturated and n-6 polyunsaturated fat diets reduce phosphorylation of insulin receptor substrate-1 and protein kinase B in muscle during the initial stages of in vivo insulin stimulation. Endocrinology 146, 5596–5603, 2005.10.1210/en.2005-048116150913
]Search in Google Scholar
[
Gao D, Nong S, Huang X, Lu Y, Zhao H, Lin Y, Man Y, Wang S, Yang J, Li J. The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways. J Biol Chem 285, 29965–29973, 2010.10.1074/jbc.M110.128694294326120647313
]Search in Google Scholar
[
Gorgisen G, Gulacar IM, Ozes ON. The role of insulin receptor substrate (IRS) proteins in oncogenic transformation. Cell Mol Biol (Noisy-le-grand), 63, 1–5, 2017.10.14715/cmb/2017.63.1.128234626
]Search in Google Scholar
[
He J, Qiu LX, Wang MY. Polymorphisms in the XPG gene and risk of gastric cancer in Chinese populations. Hum Genet 131, 1235–1244, 2012.10.1007/s00439-012-1152-822371296
]Search in Google Scholar
[
Hevko U, Kozak K, Krynytska I, Marushchak M. Diagnostic value of a complete blood count in type 2 diabetes mellitus and comorbidities. Arch Balk Medical Union 55, 601–607, 2020.10.31688/ABMU.2020.55.4.06
]Search in Google Scholar
[
Hosseini S, Alipour M, Zakerkish M, Cheraghian B, Ghandil P. Effects of epigallocatechin gallate on total antioxidant capacity, biomarkers of systemic low-grade inflammation and metabolic risk factors in patients with type 2 diabetes mellitus: the role of FTO-rs9939609 polymorphism. Arch Med Sci 17, 2021.10.5114/aoms.2020.95903864149134900054
]Search in Google Scholar
[
International Diabetes Federation. Diabetes facts & figures, 2019. (online) Available at: https://www.idf.org/aboutdiabetes/what-is-diabetes/facts-figures.html. [Accessed 2020 Aug 21].
]Search in Google Scholar
[
Kaiser AB, Zhang N, Van Der Pluijm W. Global prevalence of type 2 diabetes over the next ten years (2018–2028). Diabetes 67, 202, 2018.10.2337/db18-202-LB
]Search in Google Scholar
[
Kilpelainen TO, Zillikens MC, Stancakova A, et al. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 43, 753–760, 2011.
]Search in Google Scholar
[
Kojta I, Chacinska M, Blachnio-Zabielska A. Obesity, Bioactive Lipids, and Adipose Tissue Inflammation in Insulin Resistance. Nutrients 12, 1305, 2020.10.3390/nu12051305728499832375231
]Search in Google Scholar
[
Liu M, Wang L, Li X, Wu Y, Yin F, Liu J. Trilobatin ameliorates insulin resistance through IRS-AKT-GLUT4 signaling pathway in C2C12 myotubes and ob/ob mice. Chin Med 15, 110, 2020.10.1186/s13020-020-00390-2755253033062046
]Search in Google Scholar
[
Marushchak М, Krynytska I, Mazur L, Klishch I, Gabor G, Antonyshyn I. The relationship between experimental alimentary obesity and hard tooth tissues mineralization. Jord Med J 51, 25–33, 2017.10.12816/0039753
]Search in Google Scholar
[
Melikhova S, Shevcova V, Zujkova A, Kotova Ju. Studying of comorbid pathology at the 2 type diabetes as the metabolic syndrome. Russ Arch Int Med 8, 366–371, 2018.10.20514/2226-6704-2018-0-5-366-371
]Search in Google Scholar
[
Marushchak M, Maksiv K, Krynytska I. ACE gene I/D polymorphism and arterial hypertension in patients with COPD. Pneumologia 68, 114–119, 2019.10.2478/pneum-2019-0039
]Search in Google Scholar
[
Marushchak M, Hevko U, Krynytska I, Danylevych Y, Danchak S, Mazur L. Does comorbid obesity or chronic pancreatitis influence the choice and effectiveness of glucose-lowering therapy in type-2 diabetes patients? Arch Balk Med Union 56, 24–32, 2021.10.31688/ABMU.2021.56.1.03
]Search in Google Scholar
[
Menting JG, Whittaker J, Margetts MB, et al. How insulin engages its primary binding site on the insulin receptor. Nature 493, 24–245, 2013.10.1038/nature11781379363723302862
]Search in Google Scholar
[
Minchenko DO, Davydov VV, Budreiko OA, Moliavko OS, Kulieshova DK, Tiazhka OV, Minchenko OH. The expression of CCN2, IQSEC, RSPO1, DNAJC15, RIPK2, IL13RA2, IRS1, and IRS2 genes in blood of obese boys with insulin resistance. Fiziol Zh 61, 10–18, 2015.10.15407/fz61.01.01026040030
]Search in Google Scholar
[
Piepoli MF, Hoes AW, Agewall S, et al. European Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J 37, 2315–2381, 2016.10.1093/eurheartj/ehw106498603027222591
]Search in Google Scholar
[
Posokhova K, Stechyshyn I, Krynytska I, Marushchak M, Birchenko I, Klishch I. Comparative study of the effect of various forms of quercetin on experimental diabetes. Rom J Diabet Nutr Metab Dis 25, 383–388, 2018.10.2478/rjdnmd-2018-0046
]Search in Google Scholar
[
Qi Q, Bray GA, Smith SR, Hu FB, Sacks FM, Qi L. Insulin receptor substrate 1 gene variation modifies insulin resistance response to weight-loss diets in a 2-year randomized trial: the preventing overweight using novel dietary strategies (POUNDS LOST) trial. Circulation 124, 563–571, 2011.10.1161/CIRCULATIONAHA.111.025767317118921747052
]Search in Google Scholar
[
Rung J, Cauchi S, Albrechtsen A, et al. Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet 41, 1110–1115, 2009.10.1038/ng.44319734900
]Search in Google Scholar
[
Samuel VT, Petersen KF, Shulman GI. Lipid-induced insulin resistance: unravelling the mechanism. Lancet 375, 2267–2277, 2010.10.1016/S0140-6736(10)60408-4
]Search in Google Scholar
[
Shalimova A. Association of IRS>1 gene polymorphism with violations of blood lipid spectrum in patients with essential hypertension and concomitant type 2 diabetes. Family Med 3, 102–104, 2015.
]Search in Google Scholar
[
Shu XO, Long J, Cai Q, et al. Identification of new genetic risk variants for type 2 diabetes. PLoS Genet 6, e1001127, 2010.10.1371/journal.pgen.1001127294073120862305
]Search in Google Scholar
[
So WY, Ng MC, Lee SC, Sanke T, Lee HK, Chan JC. Genetics of type 2 diabetes mellitus. Hong Kong Med J 6, 69–76, 2000.
]Search in Google Scholar
[
Vassy JL, Hivert MF, Porneala B, Dauriz M, Florez JC, Dupuis J, Siscovick DS, Fornage M, Rasmussen-Torvik LJ, Bouchard C, Meigs JB. Polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes 63, 2172–2182, 2014.10.2337/db13-1663403011424520119
]Search in Google Scholar
[
Voloshin O, Glubochenko O Pankiv I, Glubochenko V, Malkovich N. Peculiarities of phytotherapy of diabetes mellitus through the prism of comorbidity and prevention of complications (review of literature). Int J Endocrinol 15, 258–267, 2019.10.22141/2224-0721.15.3.2019.172113
]Search in Google Scholar
[
Yang Q, Vijayakumar A, Kahn BB. Metabolites as regulators of insulin sensitivity and metabolism. Nat Rev Mol Cell Biol 19, 654–672, 2018.10.1038/s41580-018-0044-8638050330104701
]Search in Google Scholar
[
Yang X, Nath A, Opperman MJ, Chan C. The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells. Mol Biol Cell 21, 3449–3458, 2010.10.1091/mbc.e10-06-0481294748020685959
]Search in Google Scholar
[
Yiannakouris N, Cooper JA, Shah S, et al. IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk. Nutr Metab Cardiovas Dis 22, 1024–1030, 2012.10.1016/j.numecd.2011.05.009365717921917432
]Search in Google Scholar
[
Yousef AA, Behiry EG, Allah WMA, Hussien AM, Abdelmoneam AA, Imam MH, Hikal DM. IRS-1 genetic polymorphism (r.2963G>A) in type 2 diabetes mellitus patients associated with insulin resistance. Appl Clin Genet 11, 99–106, 2018.
]Search in Google Scholar
[
Yu C, Chen Y, Cline GW, et al. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem 277, 50230–50236, 2002.10.1074/jbc.M20095820012006582
]Search in Google Scholar
[
Zhang Y, Yang S, Zhang M, Wang Z, He X, Hou Y, Bai G. Glycyrrhetinic acid improves insulin-response pathway by regulating the balance between the Ras/MAPK and PI3K/Akt pathways. Nutrients 11, 604, 2019.10.3390/nu11030604647047330871060
]Search in Google Scholar
[
Zhao Y, Biswas SK, Mcnulty PH, Kozak M, Jun JY, Segar L. PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates. Am J Physiol Cell Physiol 300, 1375–1385, 2011.10.1152/ajpcell.00670.2008311862721325637
]Search in Google Scholar
[
Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol 14, 88–98, 2018.10.1038/nrendo.2017.15129219149
]Search in Google Scholar
[
Zhuravleva L, Shekhovtsova Yu. Comorbidity of chronic pancreatitis and diabetes type 2: possible options of pharmacoteraphy. Practical Doctor 5, 21–25, 2016.
]Search in Google Scholar