Clozapine impact on FosB/ΔFosB expression in stress preconditioned rats: response to a novel stressor

Alibhai IN, Green TA, Potashkin JA, Nestler EJ. Regulation of fosB and DeltafosB mRna expression: in vivo and in vitro studies. Brain Res 1143, 22–33, 2007.10.1016/j.brainres.2007.01.069Search in Google Scholar

Atkins JB, Chlan-Fourney J, Nye HE, Hiroi N, Carlezon WA Jr, Nestler EJ. Region-specific induction of deltaFosB by repeated administration of typical versus atypical antipsychotic drugs. Synapse 33, 118–128, 1999.1040089010.1002/(SICI)1098-2396(199908)33:2<118::AID-SYN2>3.0.CO;2-LSearch in Google Scholar

Bubser M, Deutch AY. Stress induces Fos expression in neurons of the thalamic paraventricular nucleus that innervate limbic forebrain sites. Synapse 32, 13–22, 1999.10.1002/(SICI)1098-2396(199904)32:1<13::AID-SYN2>3.0.CO;2-ROpen DOISearch in Google Scholar

Chen J, Kelz MB, Hope BT, Nakabeppu Y, Nestler EJ. Chronic Fos-related antigens: stable variants of deltaFosB induced in brain by chronic treatments. J Neurosci 17, 4933–4941, 1997.918553110.1523/JNEUROSCI.17-13-04933.1997Search in Google Scholar

Dietz DM, Kennedy PJ, Sun H, Maze I, Gancarz AM, Vialou V, Koo JW, Mouzon E, Ghose S, Tamminga CA, Nestler EJ.ΔFosB induction in prefrontal cortex by antipsychotic drugs is associated with negative behavioral outcomes. Neuropsychopharmacology 39, 538–544, 2014.10.1038/npp.2013.255Search in Google Scholar

Grande C, Zhu H, Martin AB, Lee M, Ortiz O, Hiroi N, Moratalla R. Chronic treatment with atypical neuroleptics induces striosomal FosB/DeltaFosB expression in rats. Biol Psychiatry 55, 457–463, 2004.10.1016/j.biopsych.2003.08.00815023572Open DOISearch in Google Scholar

Hiroi N, Graybiel AM. Atypical and typical neuroleptic treatments induce distinct programs of transcription factor expression in the striatum. J Comp Neurol 374, 70–83, 1996.10.1002/(SICI)1096-9861(19961007)374:1<70::AID-CNE5>3.0.CO;2-KSearch in Google Scholar

Kelz MB, Chen J, Carlezon WA Jr, Whisler K, Gilden L, Beckmann AM, Steffen C, Zhang YJ, Marotti L, Self DW, Tkatch T, Baranauskas G, Surmeier DJ, Neve RL, Duman RS, Picciotto MR, Nestler EJ. Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine. Nature 401, 272–276, 1999.10.1038/45790Search in Google Scholar

Kim HW, Cheon Y, Modi HR, Rapoport SI, Rao JS. Effects of chronic clozapine administration on markers of arachidonic acid cascade and synaptic integrity in rat brain. Psychopharmacology (Berl) 222, 663–674, 2012.10.1007/s00213-012-2671-7Search in Google Scholar

Kiss A, Majercikova Z. Repeated asenapine treatment does not participate in the mild stress induced FosB/ΔFosB expression in the rat hypothalamic paraventricular nucleus neurons. Neuropeptides 61, 57–65, 2017.10.1016/j.npep.2016.10.00327756486Open DOISearch in Google Scholar

Kontkanen O, Lakso M, Wong G, Castren E. Chronic antipsychotic drug treatment induces long-lasting expression of fos and jun family genes and activator protein 1 complex in the rat prefrontal cortex. Neuropsychopharmacology 27, 152–162, 2002.10.1016/S0893-133X(02)00289-0Search in Google Scholar

Kovacs KJ. c-Fos as a transcription factor: a stressful (re)view from a functional map. Neurochem Int 33, 287–297, 1998.984021910.1016/S0197-0186(98)00023-0Search in Google Scholar

Majercikova Z, Horvathova L, Osacka J, Pecenak J, Kiss A. Impact of repeated asenapine treatment on FosB/ΔFosB expression in the forebrain structures under normal conditions and mild stress preconditioning in the rat. Brain Res Bull 127, 29–37, 2016.10.1016/j.brainresbull.2016.08.008Search in Google Scholar

McClung CA, Nestler EJ. Regulation of gene expression and cocaine reward by CREB and DeltaFosB. Nat Neurosci 6, 1208–1215, 2003.10.1038/nn1143Open DOISearch in Google Scholar

Melia KR, Ryabinin AE, Schroeder R, Bloom FE, Wilson MC. Induction and habituation of immediate early gene expression in rat brain by acute and repeated restraint stress. J Neurosci 14, 5929–5938, 1994.10.1523/JNEUROSCI.14-10-05929.19947931554Open DOISearch in Google Scholar

Morrow BA, Elsworth JD, Lee EJ, Roth RH. Divergent effects of putative anxiolytics on stress-induced fos expression in the mesoprefrontal system of the rat. Synapse 36, 143–154, 2000.1076706110.1002/(SICI)1098-2396(200005)36:2<143::AID-SYN7>3.0.CO;2-HSearch in Google Scholar

Nestler EJ, Barrot M, Self DW. DeltaFosB: a sustained molecular switch for addiction. Proc Natl Acad Sci U S A 98, 11042–11046, 2001.10.1073/pnas.191352698Open DOISearch in Google Scholar

Osacka J, Szelle Cernackova A, Horvathova L, Majercikova Z, Pirnik Z, Kiss A. Clozapine impact on c-Fos expression in mild stress preconditioned male rats exposed to a novelty stressor. J Neurosci Res 96, 1786–1797, 2018.3014414810.1002/jnr.24280Search in Google Scholar

Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 4th edition. Academic Press, New York, USA, 1998.Search in Google Scholar

Perrotti LI, Hadeishi Y, Ulery PG, Barrot M, Monteggia L, Duman RS, Nestler EJ. Induction of deltaFosB in rewardrelated brain structures after chronic stress. J Neurosci 24, 10594–10602, 2004.10.1523/JNEUROSCI.2542-04.200415564575Open DOISearch in Google Scholar

Robertson GS, Lee CJ, Sridhar K, Nakabeppu Y, Cheng M, Wang YM, Caron MG. Clozapine-, but not haloperidol-, induced increases in deltaFosB-like immunoreactivity are completely blocked in the striatum of mice lacking D3 dopamine receptors. Eur J Neurosci 20, 3189–3194, 2004.10.1111/j.1460-9568.2004.03774.x15579174Open DOISearch in Google Scholar

Robison AJ, Vialou V, Sun HS, Labonte B, Golden SA, Dias C, Turecki G, Tamminga C, Russo S, Mazei-Robison M, Nestler EJ. Fluoxetine epigenetically alters the CaMKIIα promoter in nucleus accumbens to regulate ΔFosB binding and antidepressant effects. Neuropsychopharmacology 39, 1178–1186, 2014.10.1038/npp.2013.319Search in Google Scholar

Sebens JB, Koch T, Ter Horst GJ, Korf J. Differential Fos-protein induction in rat forebrain regions after acute and long-term haloperidol and clozapine treatment. Eur J Pharmacol 273, 175–182, 1995.10.1016/0014-2999(94)00692-ZSearch in Google Scholar

Sebens JB, Middelveld RJ, Koch T, Ter Horst GJ, Korf J. Clozapine-induced Fos-protein expression in rat forebrain regions: differential effects of adrenalectomy and corticosterone supplement. Eur J Pharmacol 417, 149–155, 2001.10.1016/S0014-2999(01)00870-6Search in Google Scholar

Senba E, Umemoto S, Kawai Y, Noguchi K. Differential expression of fos family and jun family mRNAs in the rat hypothalamo-pituitary-adrenal axis after immobilization stress. Brain Res Mol Brain Res 24, 283–294, 1994.796836810.1016/0169-328X(94)90141-4Search in Google Scholar

Senba E, Ueyama T. Stress-induced expression of immediate early genes in the brain and peripheral organs of the rat. Neurosci Res 29, 183–207, 1997.943664510.1016/S0168-0102(97)00095-3Search in Google Scholar

Stamp JA, Herbert J. Multiple immediate-early gene expression during physiological and endocrine adaptation to repeated stress. Neuroscience 94, 1313–1322, 1999.1062506910.1016/S0306-4522(99)00368-1Search in Google Scholar

Stamp J, Herbert J. Corticosterone modulates autonomic responses and adaptation of central immediate-early gene expression to repeated restraint stress. Neuroscience 107, 465–479, 2001.10.1016/S0306-4522(01)00364-5Search in Google Scholar

Umemoto S, Kawai Y, Ueyama T, Senba E. Chronic glucocorticoid administration as well as repeated stress affects the subsequent acute immobilization stress-induced expression of immediate early genes but not that of NGFIA. Neuroscience 80, 763–773, 1997.10.1016/S0306-4522(97)00050-XOpen DOISearch in Google Scholar

Vahid-Ansari F, Nakabeppu Y, Robertson GS. Contrasting effects of chronic clozapine, Seroquel(TM) (ICI 204,636) and haloperidol administration of deltaFosB-like immunoreactivity in the rodent forebrain. Eur J Neurosci 8, 927–936, 1996.10.1111/j.1460-9568.1996.tb01579.x8743740Search in Google Scholar

Vialou V, Bagot RC, Cahill ME, Ferguson D, Robison AJ, Dietz DM, Fallon B, Mazei-Robison M, Ku SM, Harrigan E, Winstanley CA, Joshi T, Feng J, Berton O, Nestler EJ. Prefrontal cortical circuit for depressionand anxietyrelated behaviors mediated by cholecystokinin: role of ΔFosB. J Neurosci 34, 3878–3887, 2014.10.1523/JNEUROSCI.1787-13.2014395169124623766Open DOISearch in Google Scholar

Zachariou V, Bolanos CA, Selley DE, Theobald D, Cassidy MP, Kelz MB, Shaw-Lutchman T, Berton O, Sim-Selley LJ, Dileone RJ, Kumar A, Nestler EJ. An essential role for DeltaFosB in the nucleus accumbens in morphine action. Nat Neurosci 9, 205–211, 2006.10.1038/nn163616415864Open DOISearch in Google Scholar