The Determination of Thiodan and Thiodan Sulphate on Tobacco and in Smoke Condensate

A gas chromatographic method was developed for the quantitative determination of a- and b-thiodan and thiodan sulphate on tobacco and in smoke condensate in concentrations as Iow as 0.01 parts per million. A survey was made of the thiodan and thiodan sulphate content of leaf tobacco and cigarettes. Thiodan and thiodan sulphate residues in leaf tobacco were found to amount to between 0.02 and 0.3 ppm and to between less than 0.02 and 0.05 ppm respectively. Cigarettes manufactured from Virginia tobacco were found to contain between 0.1 and 0.2 ppm of thiodan and less than 0.05 ppm of thiodan sulphate. The transfer rate of thiodan and thiodan sulphate from cigarette tobacco into the mainstream smoke ranged from 14.5 % to 16.3 %