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In Silico Insights into the Efficacy of Darjeeling Himalaya’s Traditional Fermented Beverages To Combat Various High-Altitude Sicknesses


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Acharyya, S., Saha, S., Majumder, S., & Bhattacharya, M. (2021). Characterization of a mercury tolerant strain of Staphylococcus arlettae from Darjeeling hills with an account of its antibiotic resistance pattern and metabolome. Archives of Microbiology, 203, 5745-5754. Search in Google Scholar

Al Azzam, K. M., Negim, E. S., & Aboul-Enein, H. Y. (2022). ADME studies of TUG-770 (a GPR-40 inhibitor agonist) for the treatment of type 2 diabetes using SwissADME predictor: In silico study. Journal of Applied Pharmaceutical Science, 12(4), 159-169. Search in Google Scholar

Amin, M. L. (2013). P-glycoprotein inhibition for optimal drug delivery. Drug Target Insights, 7, DTIS12519. Search in Google Scholar

Arabi, M., Nasab, S. H., Lorigooini, Z., Boroujeni, S. N., Mortazavi, S. M., Anjomshoa, M., & Amini-Khoei, H. (2021). Auraptene exerts protective effects on maternal separation stress-induced changes in behavior, hippocampus, heart and serum of mice. International Immunopharmacology, 93, 107436. Search in Google Scholar

Bibak, B., Shakeri, F., Barreto, G. E., Keshavarzi, Z., Sathyapalan, T., & Sahebkar, A. (2019). A review of the pharmacological and therapeutic effects of auraptene. BioFactors, 45(6), 867-879. Search in Google Scholar

Bogaki, T., Mitani, K., Oura, Y., & Ozeki, K. (2017). Effects of ethyl-α-d-glucoside on human dermal fibroblasts. Bioscience, Biotechnology, and Biochemistry, 81(9), 1706-1711. Search in Google Scholar

Borgström, L. (1998). Local versus total systemic bioavailability as a means to compare different inhaled formulations of the same substance. Journal of Aerosol Medicine, 11(1), 55-63. Search in Google Scholar

Buels, K. S., & Fryer, A. D. (2012). Muscarinic receptor antagonists: effects on pulmonary function. Muscarinic Receptors, 317-341. Search in Google Scholar

Chandramoorthi, G. D., Piramanayagam, S., & Marimuthu, P. (2008). An insilico approach to high altitude pulmonary edema-molecular modeling of human β2 adrenergic receptor and its interaction with salmeterol and nifedipine. Journal of Molecular Modeling, 14, 849-856. Search in Google Scholar

Chauhan, G., Roy, K., Kumar, G., Kumari, P., Alam, S., Kishore, K., Panjwani, U., & Ray, K. (2019). Distinct influence of COX-1 and COX-2 on neuroinflammatory response and associated cognitive deficits during high altitude hypoxia. Neuropharmacology, 146, 138-148. Search in Google Scholar

Chen, J. F., Eltzschig, H. K., & Fredholm, B. B. (2013). Adenosine receptors as drug targets—what are the challenges?. Nature reviews Drug discovery, 12(4), 265-286. Search in Google Scholar

Chen, P. Z., He, W. J., Zhu, Z. R., Guo-Ji, E., Xu, G., Chen, D. W., & Gao, Y. Q. (2018a). Adenosine A2A receptor involves in neuroinflammation-mediated cognitive decline through activating microglia under acute hypobaric hypoxia. Behavioural Brain Research, 347, 99-107. Search in Google Scholar

Chen, C. P., Chen, C. C., Huang, C. W., & Chang, Y. C. (2018b). Evaluating molecular properties involved in transport of small molecules in stratum corneum: A quantitative structure-activity relationship for skin permeability. Molecules, 23(4), 911. Search in Google Scholar

Choi, S. H., Aid, S., & Bosetti, F. (2009). The distinct roles of cyclooxygenase-1 and-2 in neuroinflammation: implications for translational research. Trends in Pharmacological Sciences, 30(4), 174-181. Search in Google Scholar

Cieślak, M., Komoszyński, M., & Wojtczak, A. (2008). Adenosine A 2A receptors in Parkinson’s disease treatment. Purinergic Signalling, 4, 305-312. Search in Google Scholar

Clarke C. (2006). Acute mountain sickness: medical problems associated with acute and subacute exposure to hypobaric hypoxia. Postgraduate Medical Journal, 82(973), 748–753. https://doi.org/10.1136/pgmj.2006.047662 Search in Google Scholar

Daina, A., & Zoete, V. (2016). A boiled‐egg to predict gastrointestinal absorption and brain penetration of small molecules. ChemMedChem, 11(11), 1117-1121. Search in Google Scholar

Ericsson, C. D., Steffen, R., Basnyat, B., Cumbo, T. A., & Edelman, R. (2001). Infections at high altitude. Clinical Infectious Diseases, 33(11), 1887-1891. Search in Google Scholar

Ferrazzini, G., Maggiorini, M., Kriemler, S., Bärtsch, P., & Oelz, O. (1987). Successful treatment of acute mountain sickness with dexamethasone. British Medical Journal (Clinical Research Ed..), 294(6584), 1380-1382. Search in Google Scholar

Ferro, J. N. D. S., de Aquino, F. L. T., de Brito, R. G., dos Santos, P. L., Quintans, J. D. S. S., de Souza, L. C., de Araújo, A. F., Diaz, B. L., Lucca‐Júnior, W., Quintans‐Júnior, L. J., & Barreto, E. (2015). Cyclo‐ Gly‐Pro, a cyclic dipeptide, attenuates nociceptive behaviour and inflammatory response in mice. Clinical and Experimental Pharmacology and Physiology, 42(12), 1287-1295. Search in Google Scholar

Ghose, A. K., Herbertz, T., Hudkins, R. L., Dorsey, B. D., & Mallamo, J. P. (2012). Knowledge-based, central nervous system (CNS) lead selection and lead optimization for CNS drug discovery. ACS Chemical Neuroscience, 3(1), 50-68. Search in Google Scholar

Ghosh, A., Chakraborty, S., Majumder, S., & Bhattacharya, M. (2022). Comprehensive In silico Investigation Validates Two Flavonoid Compounds of Derris robusta (Roxb. ex DC.) Benth. to Supplant Remdesivir as Natural Therapeutic Remedy Against a Range of Coronaviruses. Letters in Applied NanoBioscience, 12, 4, 108 Search in Google Scholar

Gibson, G. E., & Duffy, T. E. (1981). Impaired synthesis of acetylcholine by mild hypoxic hypoxia or nitrous oxide. Journal of Neurochemistry, 36(1), 28-33. Search in Google Scholar

Graczyk, M., Przybyszewski, M., Kuźmiński, A., Tlappa, J., Mućka, J., Napiórkowska, K., Szynkiewicz, E., Żbikowska-Gotz, M., & Bartuzi, Z. (2013). Role of E-selectin and platelet endothelial cell adhesion molecule 1 in gastritis in food allergy patients. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 30(5), 271-276. Search in Google Scholar

Gupta, M., Lee, H. J., Barden, C. J., & Weaver, D. F. (2019). The blood–brain barrier (BBB) score. Journal of Medicinal Chemistry, 62(21), 9824-9836. Search in Google Scholar

Hackett, P., Rennie, D., & Levine, H. (1976). The incidence, importance, and prophylaxis of acute mountain sickness. The Lancet, 308(7996), 1149-1155. Search in Google Scholar

Hitchcock, S. A. (2012). Structural modifications that alter the P-glycoprotein efflux properties of compounds. Journal of Medicinal Chemistry, 55(11), 4877-4895. Search in Google Scholar

Imray, C., Wright, A., Subudhi, A., & Roach, R. (2010). Acute mountain sickness: pathophysiology, prevention, and treatment. Progress in Cardiovascular Diseases, 52(6), 467-484. Search in Google Scholar

Jacome-Sosa, M., Vacca, C., Mangat, R., Diane, A., Nelson, R.C., Reaney, M. J., Shen, J., Curtis, J. M., Vine, D. F., Field, C. J., & Igarashi, M. (2016). Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR: LA-cp rat [S]. Journal of Lipid Research, 57(4), 638-649. Search in Google Scholar

Janoff, E. N., Rubins, J. B., Fasching, C., Charboneau, D., Rahkola, J. T., Plaut, A. G., & Weiser, J. N. (2014). Pneumococcal IgA1 protease subverts specific protection by human IgA1. Mucosal Immunology, 7(2), 249-256. Search in Google Scholar

Johnson, T. S., Rock, P. B., Fulco, C. S., Trad, L. A., Spark, R. F., & Maher, J. T. (1984). Prevention of acute mountain sickness by dexamethasone. New England Journal of Medicine, 310(11), 683-686. Search in Google Scholar

Jung, W. C., Jang, Y. J., Kim, J. H., Park, S. S., Park, S. H., Kim, S. J., Mok, Y. J., & Kim, C.S. (2012). Expression of intercellular adhesion molecule-1 and e-selectin in gastric cancer and their clinical significance. Journal of Gastric Cancer, 12(3), 140-148. Search in Google Scholar

Juvale, I. I. A., Hamid, A. A. A., Abd Halim, K. B., & Has, A. T. C. (2022). P-glycoprotein: new insights into structure, physiological function, regulation and alterations in disease. Heliyon, e09777. Search in Google Scholar

Kapoor, R., Narula, A. S., & Anand, A. C. (2004). Treatment of acute mountain sickness and high altitude pulmonary oedema. Medical Journal Armed Forces India, 60(4), 384-387. Search in Google Scholar

Kishimoto, T. (2005). Interleukin-6: from basic science to medicine—40 years in immunology. Annual Review of Immunology, 23, 1-21. Search in Google Scholar

Laskowski, R. A., & Swindells, M. B. (2011). LigPlot+: multiple ligand–protein interaction diagrams for drug discovery. Journal of Chemical Information and Modeling, 51 (10), 2778-2786 Search in Google Scholar

Li, L., Yu, A. L., Wang, Z. L., Chen, K., Zheng, W., Zhou, J. J., Xie, Q., Yan, H. B., Ren, P., & Huang, X. (2019). Chaihu-Shugan-San and absorbed meranzin hydrate induce anti-atherosclerosis and behavioral improvements in high-fat diet ApoE-/-mice via anti-inflammatory and BDNF-TrkB pathway. Biomedicine & Pharmacotherapy, 115, p.108893. Search in Google Scholar

Li, F., Liu, K., Gray, C., Harris, P., Reynolds, C. M., Vickers, M. H., & Guan, J. (2020). Cyclic glycineproline normalizes systolic blood pressure in high-fat diet-induced obese male rats. Nutrition, Metabolism and Cardiovascular Diseases, 30(2), 339-346. Search in Google Scholar

Liang, Z. L., Zhang, X. Y., Wang, F., Zhang, K., Liu, H. F., & Liu, H. L. (2018). Understanding molecular mechanisms of Rhodiola rosea for the treatment of acute mountain sickness through computational approaches (a STROBE-compliant article). Medicine, 97(39). Search in Google Scholar

Lipinski, C. A. (2004). Lead-and drug-like compounds: the rule-of-five revolution. Drug Discovery Today: Technologies, 1(4), 337-341. Search in Google Scholar

Liu, X., Zhou, J., Zhang, T., Chen, K., Xu, M., Wu, L., Liu, J., Huang, Y., Nie, B., Shen, X., Ren, P., & Huang, X. (2021). Meranzin hydrate elicits antidepressant effects and restores reward circuitry. Behavioural Brain Research, 398, 112898. https://doi.org/10.1016/j.bbr.2020.112898 Search in Google Scholar

MacLeod-Carey, D., Solis-Céspedes, E., Lamazares, E., & Mena-Ulecia, K. (2020). Evaluation of new antihypertensive drugs designed in silico using Thermolysin as a target. Saudi Pharmaceutical Journal, 28(5), 582-592. Search in Google Scholar

Majumder, S., Ghosh, A., Chakraborty, S., Saha, S., & Bhattacharya, M. (2021). Metabolomics affirms traditional alcoholic beverage raksi as a remedy for high-altitude sickness. Journal of Ethnic Foods, 8(1), 1-10. Search in Google Scholar

Majumder, S., Chakraborty, S., Ghosh, A., & Bhattacharya, M. (2022). The Himalayan ethnic beverage tongba with therapeutic properties in high-altitude illnesses and metabolomic similarities to Japanese sake. Acta Universitatis Sapientiae, Alimentaria, 15(1), 67-83. Search in Google Scholar

Majumder, S., Ghosh, A., Saha, S., Acharyya, S., Chakraborty, S., Subba, P., Nandi, S., Sarkar, S., & Bhattacharya, M. (2023). In vitro bioactivities and gastrointestinal simulation validate ethnomedicinal efficacy of five fermented kodo-based Himalayan traditional drinks and bioaccessibility of bioactive components. Food Production, Process and Nutrition (in press) Search in Google Scholar

Morris, G. M., Goodsell, D. S., Halliday, R. S., Huey, R., Hart, W. E., Belew, R. K., & Olson, A. J. (1998). Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function. Journal of Computational Chemistry, 19(14), 1639-1662. Search in Google Scholar

Mortelmans, K., & Zeiger, E. (2000). The Ames Salmonella/microsome mutagenicity assay. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 455(1-2), 29-60. Search in Google Scholar

Natesh, R., Schwager, S. L., Sturrock, E. D., & Acharya, K. R. (2003). Crystal structure of the human angiotensin-converting enzyme–lisinopril complex. Nature, 421(6922), 551-554. Search in Google Scholar

Pajouhesh, H., and George R. Lenz. (2005). Medicinal chemical properties of successful central nervous system drugs. NeuroRx, 2, 541-553. Search in Google Scholar

Paramashivam, S. K., Elayaperumal, K., bhagavan Natarajan, B., devi Ramamoorthy, M., Balasubramanian, S., & Dhiraviam, K. N. (2015). In silico pharmacokinetic and molecular docking studies of small molecules derived from Indigofera aspalathoides Vahl targeting receptor tyrosine kinases. Bioinformation, 11(2), 73. Search in Google Scholar

Patel, D.K. (2022). Biological potential and therapeutic effectiveness of meranzin hydrate on intestinal motility. International Journal of Surgery, 100, p.106289. Search in Google Scholar

Polosa, R., & Blackburn, M. R. (2009). Adenosine receptors as targets for therapeutic intervention in asthma and chronic obstructive pulmonary disease. Trends in Pharmacological Sciences, 30(10), 528-535. Search in Google Scholar

Potts, R. O., & Guy, R. H. (1992). Predicting skin permeability. Pharmaceutical Research, 9, 663-669. Search in Google Scholar

Priest, B.T., & McDermott, J.S. (2015). Cardiac ion channels. Channels, 9(6), 352-359. Search in Google Scholar

Priya, R., Sumitha, R., Doss, C. G. P., Rajasekaran, C., Babu, S., Seenivasan, R., & Siva, R. (2015). Molecular docking and molecular dynamics to identify a novel human immunodeficiency virus inhibitor from alkaloids of Toddalia asiatica. Pharmacognosy Magazine, 11(Suppl 3), S414. Search in Google Scholar

Riaz, M. B., Khan, A. U., & Qazi, N. G. (2019). Pharmacological and computational evaluation of fig for therapeutic potential in hyperactive gastrointestinal disorders. BMC Complementary and Alternative Medicine, 19, 1-22. Search in Google Scholar

Riley, B. E., Lougheed, J. C., Callaway, K., Velasquez, M., Brecht, E., Nguyen, L., Shaler, T., Walker, D., Yang, Y., Regnstrom, K., & Diep, L. (2013). Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases. Nature Communications, 4(1), p.1982. Search in Google Scholar

Rozwarski, D. A., Vilcheze, C., Sugantino, M., Bittman, R., & Sacchettini, J. C. (1999). Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate. Journal of Biological Chemistry, 274(22), 15582-15589. Search in Google Scholar

Savioli, G., Ceresa, I. F., Gori, G., Fumoso, F., Gri, N., Floris, V., Varesi, A., Martuscelli, E., Marchisio, S., Longhitano, Y., & Ricevuti, G. (2022). Pathophysiology and therapy of high-altitude sickness: Practical approach in emergency and critical care. Journal of Clinical Medicine, 11(14), p.3937. Search in Google Scholar

Saxena, P., Hortigon‐Vinagre, M. P., Beyl, S., Baburin, I., Andranovits, S., Iqbal, S. M., Costa, A., IJzerman, A. P., Kügler, P., Timin, E., & Smith, G. L. (2017). Correlation between human ether‐a‐go‐go‐related gene channel inhibition and action potential prolongation. British Journal of Pharmacology, 174(18), 3081-3093. Search in Google Scholar

Scammell, T. E., Gerashchenko, D. Y., Mochizuki, T., McCarthy, M. T., Estabrooke, I. V., Sears, C. A., Saper, C. B., Urade, Y., & Hayaishi, O. (2001). An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons. Neuroscience, 107(4), 653-663. Search in Google Scholar

Schyman, P., Liu, R., Desai, V., & Wallqvist, A. (2017). vNN web server for ADMET predictions. Frontiers in Pharmacology, 8, p.889. Search in Google Scholar

Sekiguchi, H., Takabayashi, F., Irie, K., & Murakami, A. (2012). Auraptene attenuates gastritis via reduction of Helicobacter pylori colonization and pro-inflammatory mediator production in C57BL/6 mice. Journal of Medicinal Food, 15(7), 658-663. Search in Google Scholar

Semwal, P., Painuli, S., Badoni, H., & Bacheti, R. K. (2018). Screening of phytoconstituents and antibacterial activity of leaves and bark of Quercus leucotrichophora A. Camus from Uttarakhand Himalaya. Clinical Phytoscience, 4, 1-6. Search in Google Scholar

Sharma, P. K., Suri, T. M., Venigalla, P. M., Garg, S. K., Mohammad, G., Das, P., Sood, S., Saraya, A., & Ahuja, V. (2014). Atrophic gastritis with high prevalence of Helicobacter pylori is a predominant feature in patients with dyspepsia in a high altitude area. Tropical gastroenterology : official journal of the Digestive Diseases Foundation, 35(4), 246–251. https://doi.org/10.7869/tg.224 Search in Google Scholar

Sharma, R., Cramer, N. P., Perry, B., Adahman, Z., Murphy, E. K., Xu, X., Dardzinski, B. J., Galdzicki, Z., Perl, D. P., Dickstein, D. L., & Iacono, D. (2019). Chronic exposure to high altitude: synaptic, astroglial and memory changes. Scientific Reports, 9(1), p.16406. Search in Google Scholar

Singh, H. B., Prasad, P., & Rai, L.K. (2002). Folk medicinal plants in the Sikkim Himalayas of India. Asian Folklore Studies, 61, 295–310. Search in Google Scholar

Singh, L. C. G. (2017). High altitude dermatology. Indian Journal of Dermatology, 62(1), 59. Search in Google Scholar

Smith, C. J., Zhang, Y., Koboldt, C. M., Muhammad, J., Zweifel, B. S., Shaffer, A., Talley, J. J., Masferrer, J. L., Seibert, K., & Isakson, P. C. (1998). Pharmacological analysis of cyclooxygenase-1 in inflammation. Proceedings of the National Academy of Sciences, 95(22), 13313-13318. Search in Google Scholar

Te Riet, L., van Esch, J. H., Roks, A. J., van den Meiracker, A. H., & Danser, A. J. (2015). Hypertension: renin–angiotensin–aldosterone system alterations. Circulation research, 116(6), 960-975. Search in Google Scholar

Trott, O., & Olson, A. J. (2010). AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. Journal of Computational Chemistry, 31(2), 455-461. Search in Google Scholar

Trzaskowski, B., Latek, D., Yuan, S., Ghoshdastider, U., Debinski, A., & Filipek, S. (2012). Action of molecular switches in GPCRs-theoretical and experimental studies. Current Medicinal Chemistry, 19(8), 1090-1109. Search in Google Scholar

Willumsen, N. J., Bech, M., Olesen, S. P., Jensen, B. S., Korsgaard, M. P., & Christophersen, P. (2003). High throughput electrophysiology: new perspectives for ion channel drug discovery. Receptors and Channels, 9(1), 3-12. Search in Google Scholar

Yeerjiang, A., Maimaitiyiming, D., Yang, T., Fang, L., Aihemaitituoheti, A., Aimaiti, M., Zhang, X., & Nijiati, Y. (2023). Pomegranate Peel in the Amelioration of High-Altitude Disease: A Network Pharmacology and Molecular Docking Study of Underlying Mechanisms. Journal of Food Biochemistry, 2023, 7186747. Search in Google Scholar

Yi, H., Wang, K., Gan, X., Li, L., Zhang, Q., Xiang, J., Yuan, X., Zhang, Y., & Wang, Y. (2020). Prophylaxis of ibuprofen in acute mountain sickness: A protocol for systematic review and meta-analysis. Medicine, 99(46). Search in Google Scholar

Zhao, K., Xing, R., & Yan, X. (2021). Cyclic dipeptides: Biological activities and self‐assembled materials. Peptide Science, 113(2), e24202. Search in Google Scholar

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