Evaluation of Non-Viral Microbiota Presence in Patients with Dysplasia and Cervical Cancer

Due to the increased incidence of cervical cancer in Romania, early detection of its causes and the taking of preventive measures are imperative.

In this sense, the aim of our study was to evaluate the infectious and non-infectious risk factors associated with the occurrence of dysplasia and cervical cancer.

We conducted a study that included 250 patients who presented themselves at the gynecological office of Policlinica 2 Constanta for specialist consultation (control or treatment) during 1 year. During their visits, Pap smear, tests for identify bacterial and fungic infections were collected together with responses to a questionnaire that evaluated the presence of socio-economical and other medical risks factor associated with dysplasia and cervical cancer..

The most important identified risk factors associated with the occurrence of cervical cancer are beginning sexual activity before the age of 16, pregnancy or abortion before the age of 18, use of empirical contraceptive methods, sexual relations with more than 3 partners during life.

Higher proportion of patients with displasya of cervical cancer presented infection with different types of non-viral microorganisms compared to women with normal results.