The Haemostatic Profile in COVID-19 Patients

This study’s goal was to identify the haemostatic profile of COVID-19 patients and their relationships to disease severity and death rates. 163 COVID-19 patients were enrolled in the research, and their diagnoses were made using PCR, common symptoms, and radiological findings (CT). Patients that were hospitalized to Ali Boushaba Public Hospitalier Khenchela’s Infectology Service in 2020. Data was gathered between January 1 and June 30, 2021. In the population that was counted, patients with COVID-19 have an average age of 61.44 + 15.4 years. The gender ratio of males to women was in the range of 0.98, therefore there was no discernible male predominance. 20% of the oxygen was desaturated, and 38.6% and 6.8% of patients had significant or serious lung disease, respectively. 16.4% mortality was seen in these individuals. These individuals had a wide spectrum of biochemical anomalies, including hyperglycaemia, which had an average value of 1.94+1.22 g/L. An increase in the mean values of CRP (68.35+58.87 mg/l) was noted. About the haemostatic profile we recorded an increase in the level of D-dimer (730.49+674.87 ng/l), a decrease in prothrombin time (55.54+36.24%). The highest D-dimer value (946.40+ 568.02 ng/l) was recorded in patients with critical parenchymal involvement (≥ 75%), and a significant correlation between the D-dimer value and parenchymal involvement was noted. Furthermore, statistically the relationship of haemostatic profile with COVID-19’s severity and with clinical outcome was insignificant.