<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Osteoporosis is represented by loss of bone mass with consequent bone fragility and increased risk of fractures. Current treatment options include several classes of drugs and adjuvant use of vitamin D and calcium. The aim of this review is to study whether vitamin K2 could be of use to the actual treatment schemes as it is directly implicated in the normal metabolism of bone tissue. After consulting the current literature, we have found that vitamin K2 is able to reduce the risk of fracture in osteoporotic patients, increase osteocalcin and diminish levels of undercarboxylated osteocalcin. In conclusion, vitamin K2 has the capability of improving the outcome and evolution of osteoporosis with minimal to no adverse effects and possibly achieving higher treatment compliance.</p></abstract>

Osteoporosis is represented by loss of bone mass with consequent bone fragility and increased risk of fractures. Current treatment options include several classes of drugs and adjuvant use of vitamin D and calcium. The aim of this review is to study whether vitamin K2 could be of use to the actual treatment schemes as it is directly implicated in the normal metabolism of bone tissue. After consulting the current literature, we have found that vitamin K2 is able to reduce the risk of fracture in osteoporotic patients, increase osteocalcin and diminish levels of undercarboxylated osteocalcin. In conclusion, vitamin K2 has the capability of improving the outcome and evolution of osteoporosis with minimal to no adverse effects and possibly achieving higher treatment compliance.

Vitamin K2 in Osteoporosis Treatment

“Iuliu Haţieganu” University of Medicine and Pharmacy

Acta Medica Transilvanica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Vitamin K2 in Osteoporosis Treatment"}

Osteoporosis is represented by loss of bone mass with consequent bone fragility and increased risk of fractures. Current treatment options include several...

Vitamin K2 in Osteoporosis Treatment

Online veröffentlicht: 03. Aug. 2020

Seitenbereich: 26 - 28

Eingereicht: 15. Apr. 2020

Akzeptiert: 28. Mai 2020

DOI: https://doi.org/10.2478/amtsb-2020-0023

Schlüsselwörter
osteoporosis, vitamin k2, bone mineral density, osteocalcin, osteoporotic fractures

© 2020 Corina Adelina Zah et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Vitamin K2 in Osteoporosis Treatment

Online veröffentlicht: 03. Aug. 2020

Seitenbereich: 26 - 28

Eingereicht: 15. Apr. 2020

Akzeptiert: 28. Mai 2020

DOI: https://doi.org/10.2478/amtsb-2020-0023

Schlüsselwörterosteoporosis, vitamin k2, bone mineral density, osteocalcin, osteoporotic fractures

© 2020 Corina Adelina Zah et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
osteoporosis, vitamin k2, bone mineral density, osteocalcin, osteoporotic fractures