<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Objective.</bold> To study both the molecular discrimination of D-tartrate fermenting and non-fermenting strains of Salmonella enterica subsp. enterica serotype Paratyphi B isolated from patients with paratyphoid fever and the clinical course of this disease.<bold>Materials and methods.</bold> The isolates examined were from children aged 3 months to 9 years. A total of 33 Salmonella strains were serotyped as Salmonella Paratyphi B, with an antigenic formula based on O- and H- antigens: 1,4, [5], 12: b: 1,2 by Kauffmann–White classification.<bold>Results.</bold> Multiplex PCR analysis confirmed all tested strains as d-tartrate fermenting (dT+), also referred to as variant Java.<bold>Discussion.</bold> We found that the most common cause of paratyphoid fever among children in Bulgaria is variant Java Salmonella Paratyphi B. Most children had classic symptoms of acute gastroenteritis – fever, watery diarrhea and vomiting.</abstract>

Objective. To study both the molecular discrimination of D-tartrate fermenting and non-fermenting strains of Salmonella enterica subsp. enterica serotype Paratyphi B isolated from patients with paratyphoid fever and the clinical course of this disease.Materials and methods. The isolates examined were from children aged 3 months to 9 years. A total of 33 Salmonella strains were serotyped as Salmonella Paratyphi B, with an antigenic formula based on O- and H- antigens: 1,4, [5], 12: b: 1,2 by Kauffmann–White classification.Results. Multiplex PCR analysis confirmed all tested strains as d-tartrate fermenting (dT+), also referred to as variant Java.Discussion. We found that the most common cause of paratyphoid fever among children in Bulgaria is variant Java Salmonella Paratyphi B. Most children had classic symptoms of acute gastroenteritis – fever, watery diarrhea and vomiting.

A Study of Paratyphoid Fever in Bulgarian Children

University Hospital “Sv. George” – Plovdiv

University Hospital for Infectious and Parasitic Diseases “Prof. Ivan Kirov”, Medical University – Sofia

Acta Medica Bulgarica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"A Study of Paratyphoid Fever in Bulgarian Children"}

Objective. To study both the molecular discrimination of D-tartrate fermenting and non-fermenting strains of Salmonella enterica subsp. enterica serotype...

A Study of Paratyphoid Fever in Bulgarian Children

Online veröffentlicht: 05. Mai 2021

Seitenbereich: 59 - 62

DOI: https://doi.org/10.2478/amb-2021-0009

Schlüsselwörter
Salmonella Paratyphi B, d-tartrate fermenters, multiplex PCR, paratyphoid fever

© 2021 M. Pavlova et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

A Study of Paratyphoid Fever in Bulgarian Children

Online veröffentlicht: 05. Mai 2021

Seitenbereich: 59 - 62

DOI: https://doi.org/10.2478/amb-2021-0009

SchlüsselwörterSalmonella Paratyphi B, d-tartrate fermenters, multiplex PCR, paratyphoid fever

© 2021 M. Pavlova et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Schlüsselwörter
Salmonella Paratyphi B, d-tartrate fermenters, multiplex PCR, paratyphoid fever