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Solute Carrier Transporters in Synovial Membrane and Hoffa’s Pad of Patients with Rheumatoid Arthritis


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Al-Khan AA, Nimmo JS, Tayebi M et al (2020) Parathyroid hormone receptor 1 (PTHR1) is a prognostic indicator in canine osteosarcoma. Sci Rep 10:1564. https://doi.org/10.1038/s41598-020-58524-3 Al-KhanAA NimmoJS TayebiM 2020 Parathyroid hormone receptor 1 (PTHR1) is a prognostic indicator in canine osteosarcoma Sci Rep 10 1564 https://doi.org/10.1038/s41598-020-58524-3 Search in Google Scholar

Amrhein J, Drynda S, Schlatt L et al (2020) Tofacitinib and baricitinib are taken up by different uptake mechanisms determining the efficacy of both drugs in RA. Int J Mol Sci 21:6632. https://doi.org/10.3390/ijms21186632 AmrheinJ DryndaS SchlattL 2020 Tofacitinib and baricitinib are taken up by different uptake mechanisms determining the efficacy of both drugs in RA Int J Mol Sci 21 6632 https://doi.org/10.3390/ijms21186632 Search in Google Scholar

Beckmann J, Schubert J, Morhenn HG et al (2015) Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis. Cell Tissue Res 359:465–477. https://doi.org/10.1007/s00441-014-2036-0 BeckmannJ SchubertJ MorhennHG 2015 Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis Cell Tissue Res 359 465 477 https://doi.org/10.1007/s00441-014-2036-0 Search in Google Scholar

Beyer AL, Kaemmerer D, Sänger J et al (2021) Immunohistochemical evaluation of adaptor protein FAM159B expression in normal and neoplastic human tissues. Int J Mol Sci 22:12250. https://doi.org/10.3390/ijms222212250 BeyerAL KaemmererD SängerJ 2021 Immunohistochemical evaluation of adaptor protein FAM159B expression in normal and neoplastic human tissues Int J Mol Sci 22 12250 https://doi.org/10.3390/ijms222212250 Search in Google Scholar

Bonaventura P, Lamboux A, Albarède F (2016) A feedback loop between inflammation and Zn uptake. PLoS One 11:e0147146. https://doi.org/10.1371/journal.pone.0147146 BonaventuraP LambouxA AlbarèdeF 2016 A feedback loop between inflammation and Zn uptake PLoS One 11 e0147146 https://doi.org/10.1371/journal.pone.0147146 Search in Google Scholar

Bröer S (2008) Apical transporters for neutral amino acids: Physiology and pathophysiology. Physiology 23:95–103. https://doi.org/10.1152/physiol.00045.2007 BröerS 2008 Apical transporters for neutral amino acids: Physiology and pathophysiology Physiology 23 95 103 https://doi.org/10.1152/physiol.00045.2007 Search in Google Scholar

Bustamante MF, Oliveira PG, Garcia-Carbonell R et al (2018) Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis. Ann Rheum Dis 77:1636–1643. https://doi.org/10.1136/annrheumdis-2018-213103 BustamanteMF OliveiraPG Garcia-CarbonellR 2018 Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis Ann Rheum Dis 77 1636 1643 https://doi.org/10.1136/annrheumdis-2018-213103 Search in Google Scholar

Crowe AR, Yue W (2019) Semi-quantitative determination of protein expression using immunohistochemistry staining and analysis: An integrated protocol. Bio Protoc 9:e3465. https://doi.org/10.21769/BioProtoc.3465 CroweAR YueW 2019 Semi-quantitative determination of protein expression using immunohistochemistry staining and analysis: An integrated protocol Bio Protoc 9 e3465 https://doi.org/10.21769/BioProtoc.3465 Search in Google Scholar

Diao L, Li N, Brayman TG et al (2010) Regulation of MRP2/ABCC2 and BSEP/ABCB11 expression in sandwich cultured human and rat hepatocytes exposed to inflammatory cytokines TNF-α, IL-6, and IL-1β. J Biol Chem 285:31185–31192. https://doi.org/10.1074/jbc.M110.107805 DiaoL LiN BraymanTG 2010 Regulation of MRP2/ABCC2 and BSEP/ABCB11 expression in sandwich cultured human and rat hepatocytes exposed to inflammatory cytokines TNF-α, IL-6, and IL-1β J Biol Chem 285 31185 31192 https://doi.org/10.1074/jbc.M110.107805 Search in Google Scholar

Eektimmerman F, Swen JJ, Böhringer S et al (2018) SLC04A1, SLC22A2 and SLC28A2 variants not related to methotrexate efficacy or toxicity in rheumatoid arthritis patients. Pharmacogenomics 19:613–619. https://doi.org/10.2217/pgs-2018-0021 EektimmermanF SwenJJ BöhringerS 2018 SLC04A1, SLC22A2 and SLC28A2 variants not related to methotrexate efficacy or toxicity in rheumatoid arthritis patients Pharmacogenomics 19 613 619 https://doi.org/10.2217/pgs-2018-0021 Search in Google Scholar

Finckh A, Gilbert B, Hodkinson B et al (2022) Global epidemiology of rheumatoid arthritis. Nat Rev Rheumatol 18:591–602. https://doi.org/10.1038/s41584-022-00827-y FinckhA GilbertB HodkinsonB 2022 Global epidemiology of rheumatoid arthritis Nat Rev Rheumatol 18 591 602 https://doi.org/10.1038/s41584-022-00827-y Search in Google Scholar

Foster M, Petocz P, Samman S (2013) Inflammation markers predict zinc transporter gene expression in women with type 2 diabetes mellitus. J Nutr Biochem 24:1655–1661. https://doi.org/10.1016/j.jnutbio.2013.02.006 FosterM PetoczP SammanS 2013 Inflammation markers predict zinc transporter gene expression in women with type 2 diabetes mellitus J Nutr Biochem 24 1655 1661 https://doi.org/10.1016/j.jnutbio.2013.02.006 Search in Google Scholar

Fotiadis D, Kanai Y, Palacín M (2013) The SLC3 and SLC7 families of amino acid transporters. Mol Aspects Med 34:139–158. https://doi.org/10.1016/j.mam.2012.10.007 FotiadisD KanaiY PalacínM 2013 The SLC3 and SLC7 families of amino acid transporters Mol Aspects Med 34 139 158 https://doi.org/10.1016/j.mam.2012.10.007 Search in Google Scholar

Franke A, McGovern DP, Barrett JC et al (2010) Genome-wide meta-analysis increases to 71 the number of confirmed Crohn’s disease susceptibility loci. Nat Genet 42:1118–1125. https://doi.org/10.1038/ng.717 FrankeA McGovernDP BarrettJC 2010 Genome-wide meta-analysis increases to 71 the number of confirmed Crohn’s disease susceptibility loci Nat Genet 42 1118 1125 https://doi.org/10.1038/ng.717 Search in Google Scholar

Gallagher L, Cregan S, Biniecka M et al (2020) Insulin-resistant pathways are associated with disease activity in rheumatoid arthritis and are subject to disease modification through metabolic reprogramming: A potential novel therapeutic approach. Arthritis Rheumatol 72:896–902. https://doi.org/10.1002/art.41190 GallagherL CreganS BinieckaM 2020 Insulin-resistant pathways are associated with disease activity in rheumatoid arthritis and are subject to disease modification through metabolic reprogramming: A potential novel therapeutic approach Arthritis Rheumatol 72 896 902 https://doi.org/10.1002/art.41190 Search in Google Scholar

Giacomini KM, Huang SM, Tweedie DJ et al (2010) Membrane transporters in drug development. Nat Rev Drug Discov 9:215–236. https://doi.org/10.1038/nrd3028 GiacominiKM HuangSM TweedieDJ 2010 Membrane transporters in drug development Nat Rev Drug Discov 9 215 236 https://doi.org/10.1038/nrd3028 Search in Google Scholar

Hagenbuch B, Stieger B (2013) The SLCO (former SLC21) superfamily of transporters. Mol Aspects Med 34:396–412. https://doi.org/10.1016/j.mam.2012.10.009 HagenbuchB StiegerB 2013 The SLCO (former SLC21) superfamily of transporters Mol Aspects Med 34 396 412 https://doi.org/10.1016/j.mam.2012.10.009 Search in Google Scholar

Hediger MA, Clémençon B, Burrier RE et al (2013) The ABCs of membrane transporters in health and disease (SLC series): Introduction. Mol Aspects Med 34:95–107. https://doi.org/10.1016/j.mam.2012.12.009 HedigerMA ClémençonB BurrierRE 2013 The ABCs of membrane transporters in health and disease (SLC series): Introduction Mol Aspects Med 34 95 107 https://doi.org/10.1016/j.mam.2012.12.009 Search in Google Scholar

Jang S, Kwon EJ, Lee JJ (2022) Rheumatoid arthritis: Pathogenic roles of diverse immune cells. Int J Mol Sci 23:905. https://doi.org/10.3390/ijms23020905 JangS KwonEJ LeeJJ 2022 Rheumatoid arthritis: Pathogenic roles of diverse immune cells Int J Mol Sci 23 905 https://doi.org/10.3390/ijms23020905 Search in Google Scholar

Jostins L, Ripke S, Weersma RK et al (2012) Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature 491:119–124. https://doi.org/10.1038/nature11582 JostinsL RipkeS WeersmaRK 2012 Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease Nature 491 119 124 https://doi.org/10.1038/nature11582 Search in Google Scholar

Koepsell H, Endou H (2004) The SLC22 drug transporter family. Pflugers Arch 447:666–676. https://doi.org/10.1007/s00424-003-1089-9 KoepsellH EndouH 2004 The SLC22 drug transporter family Pflugers Arch 447 666 676 https://doi.org/10.1007/s00424-003-1089-9 Search in Google Scholar

Komatsu N, Takayanagi H (2022) Mechanisms of joint destruction in rheumatoid arthritis - immune cell-fibroblast-bone interactions. Nat Rev Rheumatol 18:415–429. https://doi.org/10.1038/s41584-022-00793-5 KomatsuN TakayanagiH 2022 Mechanisms of joint destruction in rheumatoid arthritis - immune cell-fibroblast-bone interactions Nat Rev Rheumatol 18 415 429 https://doi.org/10.1038/s41584-022-00793-5 Search in Google Scholar

Köttgen A, Albrecht E, Teumer A et al (2013) Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet 45:145–154. https://doi.org/10.1038/ng.2500 KöttgenA AlbrechtE TeumerA 2013 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations Nat Genet 45 145 154 https://doi.org/10.1038/ng.2500 Search in Google Scholar

Kuca-Warnawin E, Burakowski T, Kurowska W et al (2011) Elevated number of recently activated T cells in bone marrow of patients with rheumatoid arthritis: A role for interleukin 15? Ann Rheum Dis 70:227–233. https://doi.org/10.1136/ard.2009.124966 Kuca-WarnawinE BurakowskiT KurowskaW 2011 Elevated number of recently activated T cells in bone marrow of patients with rheumatoid arthritis: A role for interleukin 15? Ann Rheum Dis 70 227 233 https://doi.org/10.1136/ard.2009.124966 Search in Google Scholar

Lima A, Bernardes M, Azevedo R et al (2014) SLC19A1, SLC46A1 and SLCO1B1 polymorphisms as predictors of methotrexate-related toxicity in Portuguese rheumatoid arthritis patients. Toxicol Sci 142:196–209. https://doi.org/10.1093/toxsci/kfu162 LimaA BernardesM AzevedoR 2014 SLC19A1, SLC46A1 and SLCO1B1 polymorphisms as predictors of methotrexate-related toxicity in Portuguese rheumatoid arthritis patients Toxicol Sci 142 196 209 https://doi.org/10.1093/toxsci/kfu162 Search in Google Scholar

Liu J, Zhou F, Chen Q et al (2015) Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice. Sci Rep 5:13558. https://doi.org/10.1038/srep13558 LiuJ ZhouF ChenQ 2015 Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice Sci Rep 5 13558 https://doi.org/10.1038/srep13558 Search in Google Scholar

Martínez A, Valdivia A, Pascual-Salcedo D et al (2006) Role of SLC22A4, SLC22A5, and RUNX1 genes in rheumatoid arthritis. J Rheumatol 33:842–846. https://doi.org/10.1016/j.clim.2006.04.114 MartínezA ValdiviaA Pascual-SalcedoD 2006 Role of SLC22A4, SLC22A5, and RUNX1 genes in rheumatoid arthritis J Rheumatol 33 842 846 https://doi.org/10.1016/j.clim.2006.04.114 Search in Google Scholar

Mirdamadi K, Kwok J, Nevo O et al (2021) Impact of Th-17 cytokines on the regulation of transporters in human placental explants. Pharmaceutics 13:881. https://doi.org/10.3390/pharmaceutics13060881 MirdamadiK KwokJ NevoO 2021 Impact of Th-17 cytokines on the regulation of transporters in human placental explants Pharmaceutics 13 881 https://doi.org/10.3390/pharmaceutics13060881 Search in Google Scholar

Mueckler M, Thorens B (2013) The SLC2 (GLUT) family of membrane transporters. Mol Aspects Med 34:121–138. https://doi.org/10.1016/j.mam.2012.07.001 MuecklerM ThorensB 2013 The SLC2 (GLUT) family of membrane transporters Mol Aspects Med 34 121 138 https://doi.org/10.1016/j.mam.2012.07.001 Search in Google Scholar

Pawlik A, Paradowska-Gorycka A, Safranow K et al (2019) SLC22A5 polymorphism associated with risk of extra-articular manifestations in rheumatoid arthritis patients. Reumatologia 57:3–7. https://doi.org/10.5114/reum.2019.83233 PawlikA Paradowska-GoryckaA SafranowK 2019 SLC22A5 polymorphism associated with risk of extra-articular manifestations in rheumatoid arthritis patients Reumatologia 57 3 7 https://doi.org/10.5114/reum.2019.83233 Search in Google Scholar

Sanna S, Busonero F, Maschio A et al (2009) Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia. Hum Mol Genet 18:2711–2718. https://doi.org/10.1093/hmg/ddp203 SannaS BusoneroF MaschioA 2009 Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia Hum Mol Genet 18 2711 2718 https://doi.org/10.1093/hmg/ddp203 Search in Google Scholar

Schlessinger A, Yee SW, Sali A et al (2013) SLC classification: An update. Clin Pharmacol Ther 94:19–23. https://doi.org/10.1038/clpt.2013.73 SchlessingerA YeeSW SaliA 2013 SLC classification: An update Clin Pharmacol Ther 94 19 23 https://doi.org/10.1038/clpt.2013.73 Search in Google Scholar

Seki M, Kawai Y, Ishii C, Yamanaka T et al (2017) Functional analysis of choline transporters in rheumatoid arthritis synovial fibroblasts. Mod Rheumatol 27:995–1003. https://doi.org/10.1080/14397595.2017.1280118 SekiM KawaiY IshiiC YamanakaT 2017 Functional analysis of choline transporters in rheumatoid arthritis synovial fibroblasts Mod Rheumatol 27 995 1003 https://doi.org/10.1080/14397595.2017.1280118 Search in Google Scholar

Sohn R, Junker M, Meurer A et al (2021) Anti-inflammatory effects of endogenously released adenosine in synovial cells of osteoarthritis and rheumatoid arthritis patients. Int J Mol Sci 22:8956. https://doi.org/10.3390/ijms22168956 SohnR JunkerM MeurerA 2021 Anti-inflammatory effects of endogenously released adenosine in synovial cells of osteoarthritis and rheumatoid arthritis patients Int J Mol Sci 22 8956 https://doi.org/10.3390/ijms22168956 Search in Google Scholar

Song W, Li D, Tao L et al (2020) Solute carrier transporters: The metabolic gatekeepers of immune cells. Acta Pharm Sin B 10:61–78. https://doi.org/10.1016/j.apsb.2019.12.006 SongW LiD TaoL 2020 Solute carrier transporters: The metabolic gatekeepers of immune cells Acta Pharm Sin B 10 61 78 https://doi.org/10.1016/j.apsb.2019.12.006 Search in Google Scholar

Tokuhiro S, Yamada R, Chang X et al (2003) An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nat Genet 35:341–348. https://doi.org/10.1038/ng1267 TokuhiroS YamadaR ChangX 2003 An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis Nat Genet 35 341 348 https://doi.org/10.1038/ng1267 Search in Google Scholar

Torres A, Pedersen B, Cobo I et al (2022a) Epigenetic regulation of nutrient transporters in rheumatoid arthritis fibroblast-like synoviocytes. Arthritis Rheumatol 74:1159–1171. https://doi.org/10.1002/art.42077 TorresA PedersenB CoboI 2022a Epigenetic regulation of nutrient transporters in rheumatoid arthritis fibroblast-like synoviocytes Arthritis Rheumatol 74 1159 1171 https://doi.org/10.1002/art.42077 Search in Google Scholar

Torres A, Pedersen B, Guma M (2022b) Solute carrier nutrient transporters in rheumatoid arthritis fibroblast-like synoviocytes. Front Immunol 13:984408. https://doi.org/10.3389/fimmu.2022.984408 TorresA PedersenB GumaM 2022b Solute carrier nutrient transporters in rheumatoid arthritis fibroblast-like synoviocytes Front Immunol 13 984408 https://doi.org/10.3389/fimmu.2022.984408 Search in Google Scholar

Wang J, Yin J, Li W et al (2020) Association between SLCO1A2 genetic variation and methotrexate toxicity in human rheumatoid arthritis treatment. J Biochem Mol Toxicol 34:e22513. https://doi.org/10.1002/jbt.22513 WangJ YinJ LiW 2020 Association between SLCO1A2 genetic variation and methotrexate toxicity in human rheumatoid arthritis treatment J Biochem Mol Toxicol 34 e22513 https://doi.org/10.1002/jbt.22513 Search in Google Scholar

Xu J, Jiang C, Cai Y et al (2020) Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes. Arthritis Res Ther 22:200. https://doi.org/10.1186/s13075-020-02296-8 XuJ JiangC CaiY 2020 Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes Arthritis Res Ther 22 200 https://doi.org/10.1186/s13075-020-02296-8 Search in Google Scholar

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