Toxoplasmosis in patient underwent stem cell transplantation, bone marrow transplantation due to multiple myeloma
Magdalena Bulek
Orcid-Profil, Aleksandra Kopyś-Wócik
Orcid-Profil, und Aleksandra Kocjan
Orcid-Profil 
Artikel-Kategorie: Original Study
Online veröffentlicht: 21. Juni 2025
Seitenbereich: 106 - 112
Eingereicht: 09. Feb. 2025
Akzeptiert: 20. Mai 2025
DOI: https://doi.org/10.2478/ahem-2025-0013
Schlüsselwörter
© 2025 Magdalena Bulek et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Introduction
Toxoplasmosis, caused by the protozoan
Materials and Methods
This case study presents a 53-year-old female patient who experienced a reactivation of ocular toxoplasmosis following hematopoietic stem cell transplantation for multiple myeloma. The patient developed inflammatory retinal changes that significantly affected her vision. Prompt diagnosis and targeted treatment markedly improved visual acuity and reduced the limitation of inflammatory lesions.
Results
In preventing toxoplasmosis, it may be beneficial to consider ophthalmologic examinations for patients before scheduled hematopoietic stem cell transplantation, both for recipients and donors.
Conclusions
The case underscores the importance of early detection and intervention in immunosuppressed patients to prevent long-term complications such as vision loss. It also highlights the value of preventive measures, including serological testing and ophthalmologic evaluation before stem cell transplantation. Such strategies are essential for identifying latent infections and mitigating the risk of reactivation in high-risk individuals.