Investigation of the effect of yarrow (Achillea millefolium ) on Ehrlich ascites tumor
Mustafa Nisari
Orcid-Profil, Neriman İnanç
Orcid-Profil, Adem Tokpınar
Orcid-Profil, Özge Al
Orcid-Profil, Sümeyye Uçar
Orcid-Profil, Mustafa Taştan
Orcid-Profil, Şükrü Ateş
Orcid-Profil und Seher Yılmaz
Orcid-Profil 
Artikel-Kategorie: Original Study
Online veröffentlicht: 20. Okt. 2022
Seitenbereich: 431 - 443
Eingereicht: 26. Juli 2021
Akzeptiert: 23. Jan. 2022
DOI: https://doi.org/10.2478/ahem-2022-0028
Schlüsselwörter
© 2022 Mustafa Nisari et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Introduction
One of the most important health problems today is cancer. The aim of this study was to investigate the in vitro effect of yarrow (Y) with known anticarcinogenic effect on Ehrlich ascites tumor (EAT).
Materials and Methods
The above-ground part (300 g) of Y was macerated with water and extracted three times for 24 hours at 37°C in a shaking water bath. In the study, EAT cells were divided into control, DMSO group 5-FU, 50, 100, 200, 400 and 800 μg/ml YP groups.
Results
At the end of the hour, it was observed that total apoptosis increased significantly in Y groups (especially 50 μg/ml) compared to the control group (
Conclusions
The results obtained showed that Y extract may have an antitumoral effect on EAT cells. It is thought that this study will contribute to studies on cancer treatment.