<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Introduction</h3>
<p><italic>Klebsiella pneumoniae</italic> is a common cause of antimicrobial-resistant opportunistic infections in hospitalized patients. Due to acquired resistance to multiple antimicrobials, <italic>K. pneumoniae</italic> is a particular threat in health care. The aim of this study was the assessment of the epidemiological situation related to the spread of symptomatic infections and colonization caused by <italic>K. pneumoniae</italic> New Delhi metallo-β-lactamase (NDM) in the Mazovian Voivodeship in 2016–2017.</p>
</sec>
<sec><h3>Materials and Methods</h3>
<p>The study included data collected between 2016 and 2017 from 168 hospitals located in and outside of Warsaw but limited to the Mazovian Voivodeship. Data was extracted from reports on suspected epidemic outbreaks and the elimination of outbreaks as well as annual reports on nosocomial infections and alarm pathogens.</p>
</sec>
<sec><h3>Results</h3>
<p>The incidence of infections caused by <italic>K. pneumoniae</italic> NDM (symptomatic and asymptomatic) was 0.96/1,000 hospitalizations in 2016 and 2.04/1,000 hospitalizations in 2017. In 2016, hospitals in the Mazovian Voivodeship reported 50 transmissions of <italic>K. pneumoniae</italic> NDM. In 2017, this value increased to 74. The risk of symptomatic infection was higher in hospitals outside of Warsaw than in hospitals in Warsaw, while risk of colonization was higher in hospitals in Warsaw.</p>
</sec>
<sec><h3>Conclusions</h3>
<p>The epidemiological situation related to infections and colonization caused by <italic>K. pneumoniae</italic> NDM in the Mazovian Voivodeship is disadvantageous, which implies the necessity to monitor anti-epidemic measures. The epidemic situation in hospitals outside of Warsaw seems to be worse compared to hospitals in Warsaw, which have higher risks of symptomatic infection caused by <italic>K. pneumoniae</italic> NDM.</p>
</sec>
</abstract>

Introduction
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections in hospitalized patients. Due to acquired resistance to multiple antimicrobials, K. pneumoniae is a particular threat in health care. The aim of this study was the assessment of the epidemiological situation related to the spread of symptomatic infections and colonization caused by K. pneumoniae New Delhi metallo-β-lactamase (NDM) in the Mazovian Voivodeship in 2016–2017.

Materials and Methods
The study included data collected between 2016 and 2017 from 168 hospitals located in and outside of Warsaw but limited to the Mazovian Voivodeship. Data was extracted from reports on suspected epidemic outbreaks and the elimination of outbreaks as well as annual reports on nosocomial infections and alarm pathogens.

Results
The incidence of infections caused by K. pneumoniae NDM (symptomatic and asymptomatic) was 0.96/1,000 hospitalizations in 2016 and 2.04/1,000 hospitalizations in 2017. In 2016, hospitals in the Mazovian Voivodeship reported 50 transmissions of K. pneumoniae NDM. In 2017, this value increased to 74. The risk of symptomatic infection was higher in hospitals outside of Warsaw than in hospitals in Warsaw, while risk of colonization was higher in hospitals in Warsaw.

Conclusions
The epidemiological situation related to infections and colonization caused by K. pneumoniae NDM in the Mazovian Voivodeship is disadvantageous, which implies the necessity to monitor anti-epidemic measures. The epidemic situation in hospitals outside of Warsaw seems to be worse compared to hospitals in Warsaw, which have higher risks of symptomatic infection caused by K. pneumoniae NDM.

Epidemiology of infections and colonization caused by <italic>Klebsiella pneumoniae</italic> NDM in the Mazovian Voivodeship in 2016–2017

Department of Social Medicine and Public Health

Medical University of Warsaw, Faculty of Medicine

Postępy Higieny i Medycyny Doświadczalnej

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Epidemiology of infections and colonization caused by  NDM in the Mazovian Voivodeship in 2016–2017

Introduction
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections in hospitalized patients. Due to acquired resistance...

K. pneumoniae NDM transmissions and number of affected patients	2016	2017
Transmissions	50 (100%)	74 (100%)
Symptomatic transmissions	19 (38%)	31 (42%)
Colonization transmissions	31 (62%)	43 (58%)
Patients with transmission of infection	360 (100%)	602 (100%)
Symptomatic patients	79 (22%)	138 (23%)
Patients with transmission of colonization	281 (78%)	464 (77%)

	2016		2017
Department	Number of symptomatic transmissions	Number of colonization transmissions	Number of symptomatic transmissions	Number of colonization transmissions
Total	19 (100%)	31 (100%)	31 (100%)	43 (100%)
Surgery	3 (15.8%)	8 (25.8%)	3 (9.68%)	7 (16.3%)
Neurology	7 (36.8%)	1 (3.2%)	4 (12.90%)	5 (11.6%)
Neonatology	0 (0%)	1 (3.2%)	0 (0%)	1 (2.3%)
Intensive care unit	0 (0%)	5 (16.1%)	13 (41.9%)	9 (20.9%)
Psychiatry	1 (5.3%)	2 (6.4%)	1 (3.2%)	1 (2.3%)
Internal medicine	8 (42.1%)	14 (45.2%)	10 (32.3%)	20 (46.5%)

Epidemiology of infections and colonization caused by Klebsiella pneumoniae NDM in the Mazovian Voivodeship in 2016–2017

Article Category: Original Study

Online veröffentlicht: 04. Juli 2022

Seitenbereich: 275 - 281

Eingereicht: 06. Okt. 2021

Akzeptiert: 14. Jan. 2022

DOI: https://doi.org/10.2478/ahem-2022-0024

Schlüsselwörter
Enterobacteriaceae, epidemiology, New Delhi metallo-β-lactamase, pathogen transmission

© 2022 Maria Pawlak et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Fig. 1

Fig. 2

Fig. 3

Transmission of K. pneumoniae NDM in the Mazovian Voivodeship in 2016–2017

The occurrence of K. pneumoniae NDM transmissions by hospital department in 2016–2017

Epidemiology of infections and colonization caused by Klebsiella pneumoniae NDM in the Mazovian Voivodeship in 2016–2017

Article Category: Original Study

Online veröffentlicht: 04. Juli 2022

Seitenbereich: 275 - 281

Eingereicht: 06. Okt. 2021

Akzeptiert: 14. Jan. 2022

DOI: https://doi.org/10.2478/ahem-2022-0024

SchlüsselwörterEnterobacteriaceae, epidemiology, New Delhi metallo-β-lactamase, pathogen transmission

© 2022 Maria Pawlak et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Fig. 1

Fig. 2

Fig. 3

Transmission of K. pneumoniae NDM in the Mazovian Voivodeship in 2016–2017

The occurrence of K. pneumoniae NDM transmissions by hospital department in 2016–2017

Schlüsselwörter
Enterobacteriaceae, epidemiology, New Delhi metallo-β-lactamase, pathogen transmission