Uneingeschränkter Zugang

The significance of homocysteine in patients with hypertension


Zitieren

Zdrojewski T., Szpakowski B., Bandosz P., Pająk A., Więcek A., Krupa-Wojciechowska B., Wyrzykowski B.: Arterial hypertension in Poland 2002. J. Hum. Hypertens., 2004, 18: 557–562 Zdrojewski T. Szpakowski B. Bandosz P. Pająk A. Więcek A. Krupa-Wojciechowska B. Wyrzykowski B. Arterial hypertension in Poland 2002 J. Hum. Hypertens 2004 18 557 56210.1038/sj.jhh.1001739Search in Google Scholar

Whelton P.K., Carey R.M., Aronow W.S., Casey D.E. Jr, Collins K.J., Dennison Himmelfarb C., DePalma S.M., Gidding S., Jamerson K.A., Jones D.W., et al.: 2017 ACC/AHA/AAPA/ABC/ACPM/ AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension, 2018; 71: 1,269–1,324 Whelton P.K. Carey R.M. Aronow W.S. Casey D.E. Jr Collins K.J. Dennison Himmelfarb C. DePalma S.M. Gidding S. Jamerson K.A. Jones D.W. et al 2017 ACC/AHA/AAPA/ABC/ACPM/ AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines Hypertension 2018 71 1,269 1,32410.1161/HYP.0000000000000066Search in Google Scholar

Lawes C.M., Vander Hoorn S., Rodgers A., International Society of Hypertension: Global burden of blood pressure-related disease, 2001. Lancet, 2008; 371: 1,513–1,518 Lawes C.M. Vander Hoorn S. Rodgers A. International Society of Hypertension: Global burden of blood pressure-related disease, 2001 Lancet 2008 371 1,513 1,51810.1016/S0140-6736(08)60655-8Search in Google Scholar

Tykarski A., Filipiak K.J., Januszewicz A., Litwin M., Narkiewicz K., Prejbisz A, Ostalska-Nowicka D., Widecka K., Kostka-Jeziorny K.: Guidelines of the Polish Society of Hypertertension 2019. Arterial Hypertens., 2019; 23: 41–87 Tykarski A. Filipiak K.J. Januszewicz A. Litwin M. Narkiewicz K. Prejbisz A Ostalska-Nowicka D. Widecka K. Kostka-Jeziorny K. Guidelines of the Polish Society of Hypertertension 2019 Arterial Hypertens 2019 23 41 8710.5603/AH.a2019.0008Search in Google Scholar

McCully K.S.: Homocysteine and the pathogenesis of atherosclerosis. Expert Rev. Clin. Pharmacol., 2015; 8: 211–219 McCully K.S. Homocysteine and the pathogenesis of atherosclerosis Expert Rev. Clin. Pharmacol 2015 8 211 21910.1586/17512433.2015.101051625653125Search in Google Scholar

Castro R., Rivera I., Blom H.J., Jakobs C., Tavares de Almeida I.: Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: An overview. J. Inherit. Metab. Dis., 2006; 29: 3–20 Castro R. Rivera I. Blom H.J. Jakobs C. Tavares de Almeida I. Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: An overview J. Inherit. Metab. Dis 2006 29 3 2010.1007/s10545-006-0106-516601863Search in Google Scholar

Kumar A., Palfrey H.A., Pathak R., Kadowitz P.J., Gettys T.W., Murthy S.N.: The metabolism and significance of homocysteine in nutrition and health. Nutr. Metab., 2017; 14: 78 Kumar A. Palfrey H.A. Pathak R. Kadowitz P.J. Gettys T.W. Murthy S.N. The metabolism and significance of homocysteine in nutrition and health Nutr. Metab 2017 14 7810.1186/s12986-017-0233-z574187529299040Search in Google Scholar

Hankey G.J.: B vitamins for stroke prevention. Stroke Vasc. Neurol., 2018; 3: 51–58 Hankey G.J. B vitamins for stroke prevention Stroke Vasc. Neurol 2018 3 51 5810.1136/svn-2018-000156604733630022794Search in Google Scholar

Waśkiewicz A., Sygnowska E., Broda G.: Dietary intake of vitamins B6, B12 and folate in relation to homocysteine serum concentration in the adult Polish population – WOBASZ Project. Kardiol Pol., 2010; 68: 275–282 Waśkiewicz A. Sygnowska E. Broda G. Dietary intake of vitamins B6, B12 and folate in relation to homocysteine serum concentration in the adult Polish population – WOBASZ Project Kardiol Pol 2010 68 275 282Search in Google Scholar

Fan R., Zhang A., Zhong F.: Association between homocysteine levels and all-cause mortality: A dose-response meta-analysis of prospective studies. Sci. Rep., 2017; 7: 4,769 Fan R. Zhang A. Zhong F. Association between homocysteine levels and all-cause mortality: A dose-response meta-analysis of prospective studies Sci. Rep 2017 7 4,76910.1038/s41598-017-05205-3550055228684797Search in Google Scholar

Waśkiewicz A., Sygnowska E., Broda G.: Homocysteine concentration and the risk of death in the adult Polish population. Kardiol. Pol., 2012; 70: 897–902 Waśkiewicz A. Sygnowska E. Broda G. Homocysteine concentration and the risk of death in the adult Polish population Kardiol. Pol 2012 70 897 902Search in Google Scholar

Strauss E., Supiński W., Radziemski A., Oszkinis G., Pawlak A.L., Głuszek J.: Is hyperhomocysteinemia a causal factor for heart failure? The impact of the functional variants of MTHFR and PON1 on ischemic and non-ischemic etiology. Int. J. Cardiol., 2017; 228: 37–44 Strauss E. Supiński W. Radziemski A. Oszkinis G. Pawlak A.L. Głuszek J. Is hyperhomocysteinemia a causal factor for heart failure? The impact of the functional variants of MTHFR and PON1 on ischemic and non-ischemic etiology Int. J. Cardiol 2017 228 37 4410.1016/j.ijcard.2016.11.21327863359Search in Google Scholar

Kong X., Ma X., Zhang C., Su H., Xu D.: Hyperhomocysteinemia increases the risk of chronic kidney disease in a Chinese middle-aged and elderly population-based cohort. Int. Urol. Nephrol., 2017; 49: 661–667 Kong X. Ma X. Zhang C. Su H. Xu D. Hyperhomocysteinemia increases the risk of chronic kidney disease in a Chinese middle-aged and elderly population-based cohort Int. Urol. Nephrol 2017 49 661 66710.1007/s11255-016-1452-3Search in Google Scholar

Homocysteine Studies Collaboration: Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis. JAMA, 2002; 288: 2015–2022 Homocysteine Studies Collaboration: Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis JAMA 2002 288 2015 202210.1001/jama.288.16.2015Search in Google Scholar

Wald D.S., Law M., Morris J.K.: Homocysteine and cadiovascular disease: Evidence on causality from a meta-analysis. BMJ, 2002; 325: 1202 Wald D.S. Law M. Morris J.K. Homocysteine and cadiovascular disease: Evidence on causality from a meta-analysis BMJ 2002 325 120210.1136/bmj.325.7374.1202Search in Google Scholar

Baszczuk A., Kopczyński Z., Thielmann A.: Endothelial dysfunction in patients with primary hypertension and hyperhomocysteinemia. Postępy Hig. Med. Dośw., 2014; 68: 91–100 Baszczuk A. Kopczyński Z. Thielmann A. Endothelial dysfunction in patients with primary hypertension and hyperhomocysteinemia Postępy Hig. Med. Dośw 2014 68 91 10010.5604/17322693.1087521Search in Google Scholar

Lai W.K., Kan M.Y.: Homocysteine-induced endothelial dysfunction. Ann. Nutr. Metab. 2015; 67: 1–12 Lai W.K. Kan M.Y. Homocysteine-induced endothelial dysfunction Ann. Nutr. Metab 2015 67 1 1210.1159/000437098Search in Google Scholar

Cheng Z., Yang X., Wang H.: Hyperhomocysteinemia and endothelial dysfunction. Curr. Hypertens. Rev., 2009; 5: 158–165 Cheng Z. Yang X. Wang H. Hyperhomocysteinemia and endothelial dysfunction Curr. Hypertens. Rev 2009 5 158 16510.2174/157340209788166940Search in Google Scholar

James S.J., Melnyk S., Pogribna M., Pogribny I.P., Caudill M.A.: Elevation in S-adenosylhomocysteine and DNA hypomethylation: Potential epigenetic mechanism for homocysteine-related pathology. J. Nutr.. 2002; 132: 2,361S–2,366S James S.J. Melnyk S. Pogribna M. Pogribny I.P. Caudill M.A. Elevation in S-adenosylhomocysteine and DNA hypomethylation: Potential epigenetic mechanism for homocysteine-related pathology J. Nutr 2002 132 2,361S 2,366S10.1093/jn/132.8.2361SSearch in Google Scholar

Brzezińska A., Balińska M.: Rola homocysteiny w procesie rozwoju zmian miażdżycowych na poziomie komórkowym. Postępy Biol. Kom., 2000; 27: 81–96 Brzezińska A. Balińska M. Rola homocysteiny w procesie rozwoju zmian miażdżycowych na poziomie komórkowym Postępy Biol. Kom 2000 27 81 96Search in Google Scholar

Tsai J.C., Kuo H.T., Chiu Y.W., Hwang S.J., Chuang H.Y., Chang J.M., Chen H.C., Lai Y.H.: Correlation of plasma homocysteine level with arterial stiffness and pulse pressure in hemodialysis patients. Atherosclerosis, 2005; 182: 121–127 Tsai J.C. Kuo H.T. Chiu Y.W. Hwang S.J. Chuang H.Y. Chang J.M. Chen H.C. Lai Y.H. Correlation of plasma homocysteine level with arterial stiffness and pulse pressure in hemodialysis patients Atherosclerosis 2005 182 121 12710.1016/j.atherosclerosis.2005.01.038Search in Google Scholar

Sen U., Mishra P.K., Tyagi N., Tyagi S.C.: Homocysteine to hydrogen sulfide or hypertension. Cell Biochem. Biophys., 2010; 57: 49–58 Sen U. Mishra P.K. Tyagi N. Tyagi S.C. Homocysteine to hydrogen sulfide or hypertension Cell Biochem. Biophys 2010 57 49 5810.1007/s12013-010-9079-ySearch in Google Scholar

Dinavahi R., Cossrow N., Kushner H., Falkner B.: Plasma homocysteine concentration and blood pressure in young adult African Americans. Am. J. Hypertens., 2003; 16: 767–770 Dinavahi R. Cossrow N. Kushner H. Falkner B. Plasma homocysteine concentration and blood pressure in young adult African Americans Am. J. Hypertens 2003 16 767 77010.1016/S0895-7061(03)00986-5Search in Google Scholar

Jacques P.F., Bostom A.G., Wilson P.W., Rich S., Rosenberg I.H., Selhub J.: Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort. Am. J. Clin. Nutr., 2001; 73: 613–621 Jacques P.F. Bostom A.G. Wilson P.W. Rich S. Rosenberg I.H. Selhub J. Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort Am. J. Clin. Nutr 2001 73 613 62110.1093/ajcn/73.3.613Search in Google Scholar

Sundström J., Sulivan L., D`Agostino R.B., Jacques P.F., Selhub J., Rosenberg I.H., Wilson P.W., Levy D., Vasan R.S.: Plasma homocysteine, hypertension incidence, and blood pressure tracking: The Framingham Heart Study. Hypertension, 2003; 42: 1,100–1,105 Sundström J. Sulivan L. D`Agostino R.B. Jacques P.F. Selhub J. Rosenberg I.H. Wilson P.W. Levy D. Vasan R.S. Plasma homocysteine, hypertension incidence, and blood pressure tracking: The Framingham Heart Study Hypertension 2003 42 1,100 1,10510.1161/01.HYP.0000101690.58391.13Search in Google Scholar

Cai W., Yin L., Yang F., Zhang L., Cheng J.: Association between Hcy levels and the CBS844ins68 and MTHFR C677T polymorphisms with essential hypertension. Biomed. Rep., 2014; 2: 861– 868 Cai W. Yin L. Yang F. Zhang L. Cheng J. Association between Hcy levels and the CBS844ins68 and MTHFR C677T polymorphisms with essential hypertension Biomed. Rep 2014 2 861 86810.3892/br.2014.357Search in Google Scholar

Golbahar J., Mostafavi E.: Association between low red blood cell 5-methyltetrahydrofolate and hyperhomocysteinaemia with hypertension: A cross-sectional study. High Blood Press Cardiovasc. Prev., 2012; 19: 229-235 Golbahar J. Mostafavi E. Association between low red blood cell 5-methyltetrahydrofolate and hyperhomocysteinaemia with hypertension: A cross-sectional study High Blood Press Cardiovasc. Prev 2012 19 229 23510.1007/BF03297635Search in Google Scholar

Muda P., Kampus P., Zilmer M., Zilmer K., Kairane C., Ristimäe T., Fischer K., Teesalu R.: Homocysteine and red blood cell glutathione as indices for middle-aged untreated essential hypertension patients. J. Hypertens., 2003; 21: 2,329– 2,333 Muda P. Kampus P. Zilmer M. Zilmer K. Kairane C. Ristimäe T. Fischer K. Teesalu R. Homocysteine and red blood cell glutathione as indices for middle-aged untreated essential hypertension patients J. Hypertens 2003 21 2,329 2,33310.1097/00004872-200312000-00022Search in Google Scholar

Kahleová R., Palyzová D., Zvára K., Zvárová J., Hrach K., Nováková I., Hyánek J., Bendlová B., Kozich V.: Essential hypertension in adolescents: Association with insulin resistance and with metabolism of homocysteine and vitamins. Am. J. Hypertens., 2002; 15: 857–864 Kahleová R. Palyzová D. Zvára K. Zvárová J. Hrach K. Nováková I. Hyánek J. Bendlová B. Kozich V. Essential hypertension in adolescents: Association with insulin resistance and with metabolism of homocysteine and vitamins Am. J. Hypertens 2002 15 857 86410.1016/S0895-7061(02)02984-9Search in Google Scholar

Sutton-Tyrrell K., Bostom A., Selhub J., Zeigler-Johnson C.: High homocysteine levels are independently related to isolated systolic hypertension in older adults. Circulation, 1997; 96: 1,745–1,749 Sutton-Tyrrell K. Bostom A. Selhub J. Zeigler-Johnson C. High homocysteine levels are independently related to isolated systolic hypertension in older adults Circulation 1997 96 1,745 1,74910.1161/01.CIR.96.6.17459323056Search in Google Scholar

Nygård O., Refsum H., Ueland P.M., Vollset S.E.: Major lifestyle determinants of plasma total homocysteine distribution: The Hordaland Homocysteine Study. Am. J. Clin. Nutr., 1998; 67: 263–270 Nygård O. Refsum H. Ueland P.M. Vollset S.E. Major lifestyle determinants of plasma total homocysteine distribution: The Hordaland Homocysteine Study Am. J. Clin. Nutr 1998 67 263 27010.1093/ajcn/67.2.2639459374Search in Google Scholar

Kennedy B.P., Farag N.H., Ziegler M.G., Mills P.J.: Relationship of systolic blood pressure with plasma homocysteine: Importance of smoking status. J. Hypertens., 2003; 21: 1,307–1,312 Kennedy B.P. Farag N.H. Ziegler M.G. Mills P.J. Relationship of systolic blood pressure with plasma homocysteine: Importance of smoking status J. Hypertens 2003 21 1,307 1,31210.1097/00004872-200307000-0001812817177Search in Google Scholar

Neugebauer S., Tarnow L., Stehouwer C., Teerlink T., Baba T., Watanabe T., Parving H.H.: Total plasma homocysteine is associated with hypertension in type I diabetic patients. Diabetologia, 2002; 45: 1,315–1,324 Neugebauer S. Tarnow L. Stehouwer C. Teerlink T. Baba T. Watanabe T. Parving H.H. Total plasma homocysteine is associated with hypertension in type I diabetic patients Diabetologia 2002 45 1,315 1,32410.1007/s00125-002-0908-412242465Search in Google Scholar

Mizrahi E.H., Noy S., Sela B.A., Fleissig Y., Arad M., Adunsky A.: Further evidence of interrelation between homocysteine and hypertension in, stroke patients: A cross-sectional study. Israel Med. Assoc. J., 2003; 5: 791–794 Mizrahi E.H. Noy S. Sela B.A. Fleissig Y. Arad M. Adunsky A. Further evidence of interrelation between homocysteine and hypertension in, stroke patients: A cross-sectional study Israel Med. Assoc. J 2003 5 791 794Search in Google Scholar

Nigwekar S.U., Kang A., Zoungas S., Cass A., Gallagher M.P., Kulshrestha S., Navaneethan S.D., Perkovic V., Strippoli G.F., Jardine M.J.: Interventions for lowering plasma homocysteine levels in dialysis patients. Cochrane Database Syst. Rev., 2016; 2,016: CD004683 Nigwekar S.U. Kang A. Zoungas S. Cass A. Gallagher M.P. Kulshrestha S. Navaneethan S.D. Perkovic V. Strippoli G.F. Jardine M.J. Interventions for lowering plasma homocysteine levels in dialysis patients Cochrane Database Syst. Rev 2016 2,016 CD00468310.1002/14651858.CD004683.pub3Search in Google Scholar

Lim U., Cassano P.A.: Homocysteine and blood pressure in the Third National Health and Nutrition Examination Survey, 1,988– 1,994. Am. J. Epidemiol., 2002; 156: 1105-1113 Lim U. Cassano P.A. Homocysteine and blood pressure in the Third National Health and Nutrition Examination Survey, 1,988– 1,994 Am. J. Epidemiol 2002 156 1105 111310.1093/aje/kwf15712480655Search in Google Scholar

Han L., Liu Y., Wang C., Tang L., Feng X., Astell-Burt T., Wen Q., Duan D., Lu N., Xu G., et al.: Determinants of hyperhomocysteinemia in healthy and hypertensive subjects: A population-based study and systematic review. Clin. Nutr., 2017; 36: 1,215–1,230 Han L. Liu Y. Wang C. Tang L. Feng X. Astell-Burt T. Wen Q. Duan D. Lu N. Xu G. et al Determinants of hyperhomocysteinemia in healthy and hypertensive subjects: A population-based study and systematic review Clin. Nutr 2017 36 1,215 1,23010.1016/j.clnu.2016.11.01127908565Search in Google Scholar

Borges M.C., Hartwig F.P., Olivera I.O., Horta B.L.: Is there a causal role for homocysteine concentration in blood pressure? A Mandelian randomization study. Am. J. Clin. Nutr., 2016; 103: 39–49 Borges M.C. Hartwig F.P. Olivera I.O. Horta B.L. Is there a causal role for homocysteine concentration in blood pressure? A Mandelian randomization study Am. J. Clin. Nutr 2016 103 39 4910.3945/ajcn.115.116038469166826675774Search in Google Scholar

Skeete J., DiPette D.J.: Relationship between homocysteine and hypertension: New data add to the debate. J. Clin. Hypertens., 2017; 19: 1,171–1,172 Skeete J. DiPette D.J. Relationship between homocysteine and hypertension: New data add to the debate J. Clin. Hypertens 2017 19 1,171 1,17210.1111/jch.13073803079728942602Search in Google Scholar

Fakhrzadeh H., Ghotbi S., Pourebrahim R., Heshmat R., Nouri M., Shafaee A., Larijani B.: Plasma homocysteine concentration and blood pressure in healthy Iranian adults: The Tehran Homocysteine Survey (2003–2004). J. Hum. Hypertens., 2005; 19: 869–876 Fakhrzadeh H. Ghotbi S. Pourebrahim R. Heshmat R. Nouri M. Shafaee A. Larijani B. Plasma homocysteine concentration and blood pressure in healthy Iranian adults: The Tehran Homocysteine Survey (2003–2004) J. Hum. Hypertens 2005 19 869 87610.1038/sj.jhh.100191116049520Search in Google Scholar

Tian T., Yang K.Q., Cui J.G., Zhou L.L., Zhou X.L.: Folic acid supplementation for stroke prevention in patients with cardiovascular disease. Am. J. Med. Sci., 2017; 354: 379–387 Tian T. Yang K.Q. Cui J.G. Zhou L.L. Zhou X.L. Folic acid supplementation for stroke prevention in patients with cardiovascular disease Am. J. Med. Sci 2017 354 379 38710.1016/j.amjms.2017.05.02029078842Search in Google Scholar

Bortolotto L.A., Safar M.E., Billaud E, Lacroix C., Asmar R., London G.M., Blacher J.: Plasma homocysteine, aortic stiffens, and renal function in hypertensive patients. Hypertension, 1999; 34: 837–842 Bortolotto L.A. Safar M.E. Billaud E Lacroix C. Asmar R. London G.M. Blacher J. Plasma homocysteine, aortic stiffens, and renal function in hypertensive patients Hypertension 1999 34 837 84210.1161/01.HYP.34.4.837Search in Google Scholar

Liu X., Sun N., Yu T., Fan F., Zheng M., Qian G., Wang B., Wang Y., Tang G., Li J., et al.: The independent and joint association of blood pressure, serum total homocysteine, and fasting serum glucose levels with brachial-ankle pulse wave velocity in Chinese hypertensive adults. Int. Heart J., 2016; 57: 627–633 Liu X. Sun N. Yu T. Fan F. Zheng M. Qian G. Wang B. Wang Y. Tang G. Li J. et al The independent and joint association of blood pressure, serum total homocysteine, and fasting serum glucose levels with brachial-ankle pulse wave velocity in Chinese hypertensive adults Int. Heart J 2016 57 627 63310.1536/ihj.16-08227628417Search in Google Scholar

Momin M., Fan F., Li J., Qin X., Jia J., Qi L., Zhang Y., Huo Y.: Associations of plasma homocysteine levels with peripheral systolic blood pressure and noninvasive central systolic blood pressure in a community-based Chinese population. Sci. Rep., 2017; 7: 6,316 Momin M. Fan F. Li J. Qin X. Jia J. Qi L. Zhang Y. Huo Y. Associations of plasma homocysteine levels with peripheral systolic blood pressure and noninvasive central systolic blood pressure in a community-based Chinese population Sci. Rep 2017 7 6,31610.1038/s41598-017-06611-3552494628740096Search in Google Scholar

Wang X.N., Ye P., Cao R.H., Yang X., Xiao W.K., Zhang Y., Bai Y.Y., Wu H.M.: Plasma homocysteine is a predictive factor for arterial stiffness: A community-based 4.8-year prospective study. J. Clin. Hypertens., 2015; 17: 594–600 Wang X.N. Ye P. Cao R.H. Yang X. Xiao W.K. Zhang Y. Bai Y.Y. Wu H.M. Plasma homocysteine is a predictive factor for arterial stiffness: A community-based 4.8-year prospective study J. Clin. Hypertens 2015 17 594 60010.1111/jch.12555803205725894449Search in Google Scholar

Sun F., Qian W., Zhang C.H., Fan J.X., Feng H.F.: Correlation of maternal serum homocysteine in first trimester with the development of gestational hypertension and preeclampsia. Med. Sci. Monit., 2017; 23: 5,396–5,401 Sun F. Qian W. Zhang C.H. Fan J.X. Feng H.F. Correlation of maternal serum homocysteine in first trimester with the development of gestational hypertension and preeclampsia Med. Sci. Monit 2017 23 5,396 5,40110.12659/MSM.905055Search in Google Scholar

Curgunlu A., Karter Y., Uzun H., Aydin S., Ertürk N., Vehid S., Simsek G., Kutlu A., Oztürk E., Erdine S.: Hyperhomocysteinemia: An additional risk factor in white coat hypertension. Int. Heart J., 2005; 46: 245–254 Curgunlu A. Karter Y. Uzun H. Aydin S. Ertürk N. Vehid S. Simsek G. Kutlu A. Oztürk E. Erdine S. Hyperhomocysteinemia: An additional risk factor in white coat hypertension Int. Heart J 2005 46 245 25410.1536/ihj.46.24515876808Search in Google Scholar

Coban E., Ozdoğan M., Ermiş C.: Plasma levels of homocysteine in patients with white-coat hypertension. Int. J. Clin. Pract., 2004; 58: 997–999 Coban E. Ozdoğan M. Ermiş C. Plasma levels of homocysteine in patients with white-coat hypertension Int. J. Clin. Pract 2004 58 997 99910.1111/j.1742-1241.2004.00013.x15605659Search in Google Scholar

Pierdomenico S.D., Bucci A., Lapenna D., Lattanzio F.M., Talone L., Cuccurullo F., Mezzetti A.: Circulating homocysteine levels in sustained and white coat hypertension. J. Hum. Hypertens., 2003; 17: 165–170 Pierdomenico S.D. Bucci A. Lapenna D. Lattanzio F.M. Talone L. Cuccurullo F. Mezzetti A. Circulating homocysteine levels in sustained and white coat hypertension J. Hum. Hypertens 2003 17 165 17010.1038/sj.jhh.100152412624606Search in Google Scholar

Yücel K., Bekçi T.T., Taner A., Kayrak M., Korucu E.N., Ünlü A.: Homocysteine levels in patients with masked hypertension. Anadolu Kardiyol. Derg., 2014; 14: 357–362 Yücel K. Bekçi T.T. Taner A. Kayrak M. Korucu E.N. Ünlü A. Homocysteine levels in patients with masked hypertension Anadolu Kardiyol. Derg 2014 14 357 36210.5152/akd.2014.468924818625Search in Google Scholar

Homocysteine Lowering Trialists’ Collaboration: Lowering blood homocysteine with folic acid based supplements: Meta-analysis of randomised trials. BMJ, 1998; 316: 894–898 Homocysteine Lowering Trialists’ Collaboration: Lowering blood homocysteine with folic acid based supplements: Meta-analysis of randomised trials BMJ 1998 316 894 89810.1136/bmj.316.7135.894Search in Google Scholar

Mangoni A.A., Sherwood R.A., Swift C.G., Jackson S.H.: Folic acid enhances endothelial function and reduces blood pressure in smokers: A randomized controlled trial. J. Intern. Med., 2002; 252: 497–503 Mangoni A.A. Sherwood R.A. Swift C.G. Jackson S.H. Folic acid enhances endothelial function and reduces blood pressure in smokers: A randomized controlled trial J. Intern. Med 2002 252 497 50310.1046/j.1365-2796.2002.01059.x12472909Search in Google Scholar

Tamai Y., Wada K., Tsuji M., Nakamura K., Sahashi Y., Watanabe K., Yamamoto K., Ando K., Nagata C.: Dietary intake of vitamin B12 and folic acid is associated with lower blood pressure in Japanese preschool children. Am. J. Hypertens., 2011; 24: 1,215–1,221 Tamai Y. Wada K. Tsuji M. Nakamura K. Sahashi Y. Watanabe K. Yamamoto K. Ando K. Nagata C. Dietary intake of vitamin B12 and folic acid is associated with lower blood pressure in Japanese preschool children Am. J. Hypertens 2011 24 1,215 1,22110.1038/ajh.2011.13321814291Search in Google Scholar

McRae M.P.: High-dose folic acid supplementation effects on endothelial function and blood pressure in hypertensive patients: A meta-analysis of randomized controlled clinical trials. J. Chiropr. Med., 2009: 8: 15–24 McRae M.P. High-dose folic acid supplementation effects on endothelial function and blood pressure in hypertensive patients: A meta-analysis of randomized controlled clinical trials J. Chiropr. Med 2009 8 15 2410.1016/j.jcm.2008.09.001269757819646382Search in Google Scholar

Qin X., Li Y., Sun N., Wang H., Zhang Y., Wang J., Li J., Xu X., Liang M., Nie J., et al.: Elevated homocysteine concentrations decrease the antihypertensive effect of angiotensin-converting enzyme inhibitors in hypertensive patients. Arterioscl. Thromb. Vasc. Biol., 2017; 37: 166–172 Qin X. Li Y. Sun N. Wang H. Zhang Y. Wang J. Li J. Xu X. Liang M. Nie J. et al Elevated homocysteine concentrations decrease the antihypertensive effect of angiotensin-converting enzyme inhibitors in hypertensive patients Arterioscl. Thromb. Vasc. Biol 2017 37 166 17210.1161/ATVBAHA.116.308515Search in Google Scholar

Wang W.W., Wang X.S., Zhang Z.R., He J.C., Xie C.L.: A meta-analysis of folic acid in combination with anti-hypertension drugs in patients with hypertension and hyperhomocysteinemia. Front. Pharmacol., 2017; 8: 585 Wang W.W. Wang X.S. Zhang Z.R. He J.C. Xie C.L. A meta-analysis of folic acid in combination with anti-hypertension drugs in patients with hypertension and hyperhomocysteinemia Front. Pharmacol 2017 8 58510.3389/fphar.2017.00585Search in Google Scholar

Sarigianni M., Dimitrakopoulos K., Tsapas A.: Non-dipping status in arterial hypertension: An overview. Curr. Vasc. Pharmacol., 2014; 12: 527–536 Sarigianni M. Dimitrakopoulos K. Tsapas A. Non-dipping status in arterial hypertension: An overview Curr. Vasc. Pharmacol 2014 12 527 53610.2174/157016111203140518173019Search in Google Scholar

Korkmaz S., Yilmaz A., Yildiz G., Kiliçli F., Içağasioğlu S.: Relationship between homocysteine and non-dipper pattern in patients with type 2 diabetes mellitus. Arg. Bras. Endocrinol Metab., 2012; 56: 285–290 Korkmaz S. Yilmaz A. Yildiz G. Kiliçli F. Içağasioğlu S. Relationship between homocysteine and non-dipper pattern in patients with type 2 diabetes mellitus Arg. Bras. Endocrinol Metab 2012 56 285 29010.1590/S0004-27302012000500002Search in Google Scholar

Cagnacci A., Cannoletta M., Volpe A.: High-dose short-term folate administration modifies ambulatory blood pressure in post menopausal women. Placebo-controlled study. Eur. J. Clin. Nutr., 2009; 63: 1,266–1,268 Cagnacci A. Cannoletta M. Volpe A. High-dose short-term folate administration modifies ambulatory blood pressure in post menopausal women. Placebo-controlled study Eur. J. Clin. Nutr 2009 63 1,266 1,26810.1038/ejcn.2009.58Search in Google Scholar

Cagnacci A., Cannoletta M., Xholi A., Piacenti I., Palma F., Palmieri B.: Folate administration decrease oxidative status and blood pressure in postmenopausal women. Eur. J. Nutr., 2015; 54: 429– 435 Cagnacci A. Cannoletta M. Xholi A. Piacenti I. Palma F. Palmieri B. Folate administration decrease oxidative status and blood pressure in postmenopausal women Eur. J. Nutr 2015 54 429 43510.1007/s00394-014-0726-8Search in Google Scholar

Dong Y.F., Zhan B.M., Hao Q.Y, Ruan Z.H., Xu Z.X., Deng M., Chen D.W., Zou Y.Q., Chen J., Li P., et al.: Plasma homocysteine levels are associated with circadian blood pressure variation in Chinese hypertensive adults. Am. J. Hypertens., 2017; 30: 1,203– 1,210 Dong Y.F. Zhan B.M. Hao Q.Y Ruan Z.H. Xu Z.X. Deng M. Chen D.W. Zou Y.Q. Chen J. Li P. et al Plasma homocysteine levels are associated with circadian blood pressure variation in Chinese hypertensive adults Am. J. Hypertens 2017 30 1,203 1,21010.1093/ajh/hpx116Search in Google Scholar

Joyeux-Faure M., Baguet J.P., Barone-Rochette G., Faure P., Sosner P., Mounier-Vehier C., Lévy P., Tamisier R., Pépin J.L.: Continuous positive airway pressure reduces night-time blood pressure and heart rate in patients with obstructive sleep apnea and resistant hypertension: The RHOOSAS Randomized Controlled Trial. Front. Neurol., 2018; 9: 318 Joyeux-Faure M. Baguet J.P. Barone-Rochette G. Faure P. Sosner P. Mounier-Vehier C. Lévy P. Tamisier R. Pépin J.L. Continuous positive airway pressure reduces night-time blood pressure and heart rate in patients with obstructive sleep apnea and resistant hypertension: The RHOOSAS Randomized Controlled Trial Front. Neurol 2018 9 31810.3389/fneur.2018.00318Search in Google Scholar

Bønaa K.H., Njølstad I., Ueland P.M. Schirmer H., Tverdal A., Steigen T., Wang H., Nordrehaug J.E., Arnesen E., Rasmussen K.: Homocysteine lowering and cardiovascular events after acute myocardial infarction. N. Engl. J. Med., 2006; 354: 1,578–1,588 Bønaa K.H. Njølstad I. Ueland P.M. Schirmer H. Tverdal A. Steigen T. Wang H. Nordrehaug J.E. Arnesen E. Rasmussen K. Homocysteine lowering and cardiovascular events after acute myocardial infarction N. Engl. J. Med 2006 354 1,578 1,58810.1056/NEJMoa055227Search in Google Scholar

VITATOPS Trial Study Group: B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: A randomised, double-blind, parallel, placebo-controlled trial. Lancet Neurol, 2010; 9: 855–865 VITATOPS Trial Study Group: B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: A randomised, double-blind, parallel, placebo-controlled trial Lancet Neurol 2010 9 855 86510.1016/S1474-4422(10)70187-3Search in Google Scholar

Saposnik G., Ray J.G., Sheridan P., McQueen M., Lonn E., Heart Outcomes Prevention Evaluation 2 Investigators: Homocysteinelowering therapy and stroke risk, severity, and disability: Additional findings from the HOPE 2 trial. Stroke, 2009; 40: 1,365–1,372 Saposnik G. Ray J.G. Sheridan P. McQueen M. Lonn E. Heart Outcomes Prevention Evaluation 2 Investigators: Homocysteinelowering therapy and stroke risk, severity, and disability: Additional findings from the HOPE 2 trial Stroke 2009 40 1,365 1,37210.1161/STROKEAHA.108.52950319228852Search in Google Scholar

Huo Y., Li J., Qin X., Huang Y., Wang X., Gottesman R.F., Tang G., Wang B., Chen D., He M., et al.: Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: The CSPPT randomized clinical trial. Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: The CSPPT randomized clinical trial. JAMA, 2015; 313:1,325–1,335 Huo Y. Li J. Qin X. Huang Y. Wang X. Gottesman R.F. Tang G. Wang B. Chen D. He M. et al Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: The CSPPT randomized clinical trial. Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: The CSPPT randomized clinical trial JAMA 2015 3131,325 1,33510.1001/jama.2015.227425771069Search in Google Scholar

Qin X., Li J., Spence J.D., Zhang Y., Li Y., Wang X., Wang B., Sun N., Chen F., Guo J., et al.: Folic acid therapy reduces the firs stroke risk associated with hypercholesterolemia among hypertensive patients. Stroke, 2016; 47: 2,805–2,812 Qin X. Li J. Spence J.D. Zhang Y. Li Y. Wang X. Wang B. Sun N. Chen F. Guo J. et al Folic acid therapy reduces the firs stroke risk associated with hypercholesterolemia among hypertensive patients Stroke 2016 47 2,805 2,81210.1161/STROKEAHA.116.01457827729579Search in Google Scholar

Li K., Zhang J., Qin Y., Wei Y.X.: Association between serum homocysteine level and obstructive sleep apnea: A meta-analysis. Biomed. Res. Int., 2017; 2017: 7234528 Li K. Zhang J. Qin Y. Wei Y.X. Association between serum homocysteine level and obstructive sleep apnea: A meta-analysis Biomed. Res. Int 2017 2017 723452810.1155/2017/7234528555502128831396Search in Google Scholar

Tao L.H., Yang K., Wu J., Mahara G., Zhang J., Zhang J.B., Ping Z., Guo X.: Association between plasma homocysteine and hypertension: Results from a cross-sectional and longitudinal analysis in Beijing adult population from 2012–2017. J. Clin. Hypertens., 2018; 20: 1,624–1,632 Tao L.H. Yang K. Wu J. Mahara G. Zhang J. Zhang J.B. Ping Z. Guo X. Association between plasma homocysteine and hypertension: Results from a cross-sectional and longitudinal analysis in Beijing adult population from 2012–2017 J. Clin. Hypertens 2018 20 1,624 1,63210.1111/jch.13398803094530362656Search in Google Scholar

Zhao M., Wu G., Li Y., Wang X., Hou F.F., Xu X., Qin X., Cai Y.: Meta-analysis of folic acid efficacy trials on stroke prevention: Onsight into effect modifiers. Neurology, 2017; 88: 1,830–1,838 Zhao M. Wu G. Li Y. Wang X. Hou F.F. Xu X. Qin X. Cai Y. Meta-analysis of folic acid efficacy trials on stroke prevention: Onsight into effect modifiers Neurology 2017 88 1,830 1,83810.1212/WNL.000000000000390928404799Search in Google Scholar

Xu R.B., Kong X., Xu B.P., Song Y., Ji M., Zhao M., Huang X., Li P., Cheng X., Chen F., et al:. Longitudinal association between fasting blood glucose concentrations and first stroke in hypertensive adults in China: Effect of folic acid intervention. Am. J. Clin. Nutr., 2017; 105: 564–570 Xu R.B. Kong X. Xu B.P. Song Y. Ji M. Zhao M. Huang X. Li P. Cheng X. Chen F. et al Longitudinal association between fasting blood glucose concentrations and first stroke in hypertensive adults in China: Effect of folic acid intervention Am. J. Clin. Nutr 2017 105 564 57010.3945/ajcn.116.14565628122783Search in Google Scholar

Meng Y., Li J., Chen X., She H., Zhao L., Peng Y., Zhang J., Shang K., Li H Yang W., et al.: Association between folic acid suplementation and retinal atherosclerosis in Chinese adults with hypertension complicated by diabetes mellitus. Front. Pharnacol., 2018; 9: 1,159 Meng Y. Li J. Chen X. She H. Zhao L. Peng Y. Zhang J. Shang K. Li H. Yang W. et al Association between folic acid suplementation and retinal atherosclerosis in Chinese adults with hypertension complicated by diabetes mellitus Front. Pharnacol 2018 9 1,15910.3389/fphar.2018.01159621892330425639Search in Google Scholar

Li Y., Liang M., Wang G., Wang B., He M., Tang G., Yin D., Xu X., Huo Y., Cui Y., et al.: Effects of folic acid therapy on the new-onset proteinuria in Chinese hypertensive patients: A post analysis of the renal substudy of CSPPT (China Stroke Primary Prevention Trial). Hypertension, 2017; 70: 300–306 Li Y. Liang M. Wang G. Wang B. He M. Tang G. Yin D. Xu X. Huo Y. Cui Y. et al Effects of folic acid therapy on the new-onset proteinuria in Chinese hypertensive patients: A post analysis of the renal substudy of CSPPT (China Stroke Primary Prevention Trial) Hypertension 2017 70 300 30610.1161/HYPERTENSIONAHA.117.0940428607125Search in Google Scholar

Li Y., Qin X., Luo L., Wang B., Huo Y., Hou, F.F., Xu X.: Folic acid therapy reduces the risk of mortality associated with heavy proteinuria among hypertensive patients. J. Hypertens., 2017; 35: 1,302–1,309 Li Y. Qin X. Luo L. Wang B. Huo Y. Hou F.F. Xu X. Folic acid therapy reduces the risk of mortality associated with heavy proteinuria among hypertensive patients J. Hypertens 2017 35 1,302 1,30910.1097/HJH.000000000000129228441699Search in Google Scholar

Bravo-Soto G.A., Madrid T.: Is folic acid supplementation useful for chronic kidney disease? Medwave, 2016; 16: e6,591 Bravo-Soto G.A. Madrid T. Is folic acid supplementation useful for chronic kidney disease? Medwave 2016 16 e6,59110.5867/medwave.2016.659127858927Search in Google Scholar

Qin X., Huo Y., Xie D., Hou F., Xu X., Wang X.: Homocysteinelowering therapy with folic acid is effective in cardiovascular disease prevention in patients with kidney disease: A meta-analysis of randomized controlled trials. Clin Nutr., 2013; 32: 722–727 Qin X. Huo Y. Xie D. Hou F. Xu X. Wang X. Homocysteinelowering therapy with folic acid is effective in cardiovascular disease prevention in patients with kidney disease: A meta-analysis of randomized controlled trials Clin Nutr 2013 32 722 72710.1016/j.clnu.2012.12.00923313356Search in Google Scholar

eISSN:
1732-2693
Sprache:
Englisch
Zeitrahmen der Veröffentlichung:
Volume Open
Fachgebiete der Zeitschrift:
Biologie, Molekularbiologie, Mikrobiologie und Virologie, Medizin, Vorklinische Medizin, Grundlagenmedizin, Immunologie